{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Epilepsy Sparks Insights","title":"Cenobamate & Fenfluramine: What's Changing for Uncontrolled Seizures? - Prof. Vicente Villanueva","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/0980b685\"></iframe>","width":"100%","height":180,"duration":937,"description":"Can newer epilepsy treatments help more people achieve seizure control - and does it matter when they're introduced? Epileptologist Vicente Villanueva shares with us findings from two studies investigating cenobamate and fenfluramine. He explains why earlier treatment may improve outcomes, how medication combinations and side effects affect quality of life, and what the research reveals about cognition, behaviour and sleep.\nChapters 📖\n00:00 Trailer & intro\n01:09 Meet Vicente Villanueva\n01:20 How epilepsy treatments have changed \n02:41 Why does drug-resistant epilepsy remain so difficult to treat? \n04:17 The FREEDON study: Why earlier cenobamate treatment matters \n05:45 Why do previous treatment failures predict poorer outcomes? \n07:50 Fenfluramine for developmental and epileptic encephalopathies (DEEs)\n09:12 Balancing seizure control and side effects \n10:14 Cognition, behaviour and quality of life \n11:00 Managing cenobamate side effects\n12:13 Finding the right combination of treatments \n14:45 The future: Treatments that change the course of epilepsy \n14:53 Closing thoughts & thanks\n🔗 Episode page and transcript\nhttps://www.epilepsysparks.com/epilepsy-sparks-insights/dre-cenobamate-fenfluramine-dravet-lgs\n🌐 More about Vicente https://epilepsysparks.com/guests/vicente-villanueva\n🌐 More Epilepsy Sparks Insights https://epilepsysparks.com/epilepsy-sparks-insights\n🎧 Listen on podcast https://share.transistor.fm/s/0980b685\n🔤 Don’t understand terms used? Check out the Epilepsy Sparks Glossary! https://epilepsysparks.com/glossary\n📲 Join us on social media!\n〰️ LinkedIn https://www.linkedin.com/company/epilepsy-sparks\n〰️ Instagram https://www.instagram.com/epilepsysparks\n〰️ Facebook https://www.facebook.com/epilepsysparks\n〰️ TikTok https://www.tiktok.com/@epilepsysparks\n〰️ Bluesky https://bsky.app/profile/epilepsysparks.bsky.social","thumbnail_url":"https://img.transistorcdn.com/ETcVcvJ4VhVWwS3naEn8WMtHF9g3yTGGq7gx0U5XJZo/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9jMzZm/NGY5NWZmMTgxMGZi/MjE0ODNkMjI2NGRk/YjJjNC5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}