{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Your Natural Dog with Angela Ardolino","title":"126. Anti-Aging Drugs for Dogs: The Truth About Extending Your Pet’s Life with Carter Easler","html":"","width":"100%","height":180,"duration":3088,"description":"As pharmaceutical companies begin rolling out anti-aging drugs for dogs, many pet parents are being told these medications can extend lifespan and prevent cognitive decline. But what are these drugs actually doing inside the body, and at what cost?\nIn this episode, Angela sits down with Carter Easler, Director of Research and Education for CBD Dog Health and MycoDog, to break down the science behind emerging longevity drugs like rapamycin and Loyal. Carter also shares insights from coordinating the Senior Dog Study on cognitive decline, as they explore how pharmaceutical interventions compare to natural strategies that work with the body’s own repair systems, including fasting, adaptogens, medicinal mushrooms, and support for the endocannabinoid system.\nIf you have a senior dog, or want to learn about supporting your aging dog before their golden years, this is an episode you won’t want to miss.\nEpisode Recap:Angela and Carter talk about the rise of anti-aging drugs for dogs on the market, and why aging is at its core, a loss of homeostasis. (00:00)Rapamycin for dogs, what it does and why it was originally developed. (04:41)Do anti-aging drugs support longevity, or interfere with the body’s natural repair processes like autophagy and cellular balance? (07:48)How fasting and restricted feeding windows naturally activate autophagy, support cellular cleanup, and may help extend lifespan in dogs. (11:10)Telomeres, “zombie cells,” and mTOR: how adaptogens, medicinal mushrooms, and hemp modulate aging pathways to support cellular balance instead of blocking the body’s natural repair systems. (16:41)Why pharmaceutical “one-target” drugs can create a narrow therapeutic window and unintended side effects, while adaptogens and medicinal mushrooms support all 12 hallmarks of aging. (20:59)The 12 hallmarks of aging explained, from telomere shortening and mitochondrial dysfunction to microbiome imbalance, and how these anti aging drugs are targeting just one of these....","thumbnail_url":"https://img.transistorcdn.com/hQTYNN7Jy3D3R2-x-ysWDodZEKOLf7oa59rZrkCS3gA/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9zaG93/LzM3NDY3LzE2NzI3/NzU2OTYtYXJ0d29y/ay5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}