{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"HealthTech Remedy","title":"Flatiron Health Clinical Research: A New Model for Faster, More Efficient Trials with Alex Deyle","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/0d6bac77\"></iframe>","width":"100%","height":180,"duration":2704,"description":"Clinical trials are notoriously slow, expensive, and inefficient, creating a major bottleneck that delays getting life-saving treatments to cancer patients. What if we could build a new research engine from the ground up, leveraging data and technology to run trials 6x faster and at a significantly lower cost? In this episode, we explore the groundbreaking work of the Flatiron Health clinical research unit, a team that is redefining what's possible in oncology research.Joined by Alex Deyle, VP & General Manager of Clinical Research at Flatiron Health, we uncover the strategies and technologies they are deploying to fix the broken trial system. From their origins as a pioneer in real-world evidence to their acquisition by Roche, Flatiron has built a unique ecosystem founded on deep integrations with community oncology EHRs. Now, they're leveraging that foundation to tackle the biggest challenges in clinical research, from protocol design to final data submission. This conversation is a must-watch for anyone interested in the future of drug development, health tech, and the mission to get new treatments to patients faster.This episode breaks down the new model for improving clinical trial efficiency. We explore Flatiron's three-pronged approach: designing smarter protocols by using real-world evidence in clinical trials to optimize eligibility criteria, accelerating clinical trial patient recruitment with AI-powered patient matching that reduces site screening effort by 95%, and lowering the massive data collection burden with innovative EHR to EDC solutions. Alex shares incredible real-world examples, including a partnership with Exact Sciences on a molecular residual disease (MRD) study that went from concept to first patient in just six months—a process that typically takes years. We also dive into their collaboration with NRG Oncology, one of the NCI's cooperative groups, to deploy their Flatiron ClinicalPipe™ technology and prove the value of a direct data...","thumbnail_url":"https://img.transistorcdn.com/Al9s4QJpRCg2VJ2YaV_fo3tDCayXbUO7NTDbnFeSAUQ/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9mNTVk/OTAwMzQxYWFiZmYy/ZWFlNzFmN2RmOTcx/MDMwNy5wbmc.webp","thumbnail_width":300,"thumbnail_height":300}