{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"萌喵读文献-肿瘤学","title":"今日肿瘤学最高分文献 - 2024-12-12","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/2850a493\"></iframe>","width":"100%","height":180,"duration":4,"description":"欢迎收听今日的医学突破播客！最新研究发现，维生素E琥珀酸盐（VES）能作为脂肪团和肥胖相关蛋白（FTO）的降解剂，通过增强肿瘤细胞中FTO的降解，抑制肿瘤生长并增强对免疫疗法的响应。这项研究揭示了FTO蛋白降解的分子机制，并指出VES作为一种饮食降解剂，能够抑制肿瘤生长并克服免疫疗法的耐药性。这一发现不仅为癌症治疗提供了新思路，也为免疫疗法的优化开辟了新途径。不要错过这一激动人心的进展，继续关注我们，了解更多医学前沿动态！","thumbnail_url":"https://img.transistorcdn.com/3WX36CzvFOrNjlF7WfWjzS4HdcMIMmzMs2bmPS-ejLU/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS83NDNm/MjQ1N2E5NjhjMzVj/NjM0ZTA3YzY2NDE2/ZmIyMi5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}