{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Kaya Cast","title":"Endocannabinoid System Demystified: Dr. Bonni's Guide to Medicinal Cannabis","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/340bd5ce\"></iframe>","width":"100%","height":180,"duration":3810,"description":"On this Kaya Cast episode, host Tommy Truong sits down with Dr. Bonni Goldstein of Goldstein Wellness to unpack the science, medicine, and business of cannabis in epilepsy and beyond. Dr. Goldstein is the Chief Medical Advisor for Neurotech International, helping to develop effective cannabinoid-based formulations for autism and other pediatric neurologic conditions.From the endocannabinoid system to multimodal cannabinoids like CBD, CBDV, CBG and CBDA, they discuss how clinicians tailor regimens for pediatric and adult patients, why dosing is start low and go slow, and what the latest clinical data show about seizure reduction and quality of life. Bonni shares her journey from pediatric emergency medicine to medical cannabis, the Charlotte story that helped launch CBD in epilepsy, and practical dosing, safety, and drug interaction considerations. They also talk about the business side: educating clinicians, ensuring product quality, and Goldstein Wellness's free clinician education program with about 50 videos, plus a patient-facing network of vetted cannabis clinicians. If you’re a dispensary executive, grower, or clinician, this episode offers actionable insights on education, regulation, and patient-centered cannabis care. Find out more about Goldstein Wellness at:https://goldsteinwellness.com/https://www.linkedin.com/in/bonnigoldsteinmd/https://www.linkedin.com/company/goldstein-wellness/ 00:00 CBD Seizure Success00:17 Meet Dr Bonni00:58 From ER to Cannabis02:00 Cancer Patient Turning Point04:30 ECS Explained Simply08:16 Receptors and Evolution11:44 Dysfunction and Conditions13:40 Research Barriers and COVID16:42 CBD for Intractable Epilepsy19:51 Charlotte Figi Breakthrough24:13 How CBD Calms Seizures26:47 Dosing and Other Cannabinoids29:54 Beyond Seizure Control31:08 Medical vs Recreational Divide31:50 Medical vs Adult Use32:39 Teaching Cannabis Literacy34:26 Beyond CBD and THC34:53 CBG Effects and Dosing38:53 CBG Biomarkers Research41:16 CBN and Sleep...","thumbnail_url":"https://img.transistorcdn.com/Nlxm0QKHrXkZaRTzk1hspsaKZ09jzx0wFKCGF_C375k/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS82ZWU3/YmZiMDM5Y2VhZTEw/ODE5ZDdjZWY4NTVi/Mjg1My5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}