{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Kaya Cast","title":"Endocannabinoid System Demystified: Dr. Bonni's Guide to Medicinal Cannabis","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/340bd5ce\"></iframe>","width":"100%","height":180,"duration":3810,"description":"On this Kaya Cast episode, host Tommy Truong sits down with Dr. Bonni Goldstein of Goldstein Wellness to unpack the science, medicine, and business of cannabis in epilepsy and beyond. Dr. Goldstein is the Chief Medical Advisor for Neurotech International, helping to develop effective cannabinoid-based formulations for autism and other pediatric neurologic conditions.\nFrom the endocannabinoid system to multimodal cannabinoids like CBD, CBDV, CBG and CBDA, they discuss how clinicians tailor regimens for pediatric and adult patients, why dosing is start low and go slow, and what the latest clinical data show about seizure reduction and quality of life. Bonni shares her journey from pediatric emergency medicine to medical cannabis, the Charlotte story that helped launch CBD in epilepsy, and practical dosing, safety, and drug interaction considerations. They also talk about the business side: educating clinicians, ensuring product quality, and Goldstein Wellness's free clinician education program with about 50 videos, plus a patient-facing network of vetted cannabis clinicians. If you’re a dispensary executive, grower, or clinician, this episode offers actionable insights on education, regulation, and patient-centered cannabis care.\nFind out more about Goldstein Wellness at:\nhttps://goldsteinwellness.com/\nhttps://www.linkedin.com/in/bonnigoldsteinmd/\nhttps://www.linkedin.com/company/goldstein-wellness/\n00:00 CBD Seizure Success\n00:17 Meet Dr Bonni\n00:58 From ER to Cannabis\n02:00 Cancer Patient Turning Point\n04:30 ECS Explained Simply\n08:16 Receptors and Evolution\n11:44 Dysfunction and Conditions\n13:40 Research Barriers and COVID\n16:42 CBD for Intractable Epilepsy\n19:51 Charlotte Figi Breakthrough\n24:13 How CBD Calms Seizures\n26:47 Dosing and Other Cannabinoids\n29:54 Beyond Seizure Control\n31:08 Medical vs Recreational Divide\n31:50 Medical vs Adult Use\n32:39 Teaching Cannabis Literacy\n34:26 Beyond CBD and THC\n34:53 CBG Effects and Dosing\n38:53 CBG Biomarkers Research...","thumbnail_url":"https://img.transistorcdn.com/Nlxm0QKHrXkZaRTzk1hspsaKZ09jzx0wFKCGF_C375k/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS82ZWU3/YmZiMDM5Y2VhZTEw/ODE5ZDdjZWY4NTVi/Mjg1My5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}