{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Answers from the Lab","title":"Whole Exome Sequencing Reflex Test Offers Cost-Effective Diagnosis: Cherisse Marcou, Ph.D., and Kristen Rasmussen, M.S., CGC","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/34602bf7\"></iframe>","width":"100%","height":180,"duration":1333,"description":"Cherisse Marcou, Ph.D., and Kristen Rasmussen, M.S., CGC, explain how Mayo Clinic Laboratories' WESPR whole exome sequencing reflex test provides cost-effective diagnosis of complex genetic conditions. Using samples and data from previous targeted gene panels, WESPR's wider net can identify undetected genetic variants.\n(00:32)\nWould each of you share a little bit about yourselves and your background?\n \n(01:42)\nCould you provide us with an overview of the whole exome reflexing panel?\n \n(02:53)\n Is this different from our whole exome sequencing panel and our whole exome reanalysis panel?\n \n(04:00)\n Tell us more about who benefits from this test.\n \n(06:17)\n What is the clinical utility of this testing?\n \n(08:07)\nWould you help providers understand how to go about ordering?\n \n(11:23)\nCould you tell us more about the types of variants identified by this test?\n \n(13:39)\nBased on those performance characteristics, how does our test match up to other exome tests available in the market?\n \n(14:30)\nAre there any other unique features you would like to highlight?\n \n(15:57)\nWhat is the turnaround time for the reflex panel?\n \n(16:14)\nCan the results from the WESPR test be reanalyzed in the future as new genetic knowledge emerges?\n \n(16:56)\nHow are variants reported, especially variants of uncertain significance? And does the report include recommendations?\n \n(19:31)\nWould you summarize the benefits of the WESPR at Mayo Clinic Laboratories?","thumbnail_url":"https://img.transistorcdn.com/jhRCftFebxnTMwoIbA_WoqrSKwFRD_Y2kbh0JDjhx14/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9lYjNj/ZDc0NTE0MWNlOWRl/YzRiN2Q3NDg2Mjg5/YWE4MS5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}