{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"The Curious Cardiologist","title":"Genomic Medicine, Not Guesswork: How Your Genes Shape Diet, Drugs & Supplements","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/3925105b\"></iframe>","width":"100%","height":180,"duration":3924,"description":"In this episode of The Curious Cardiologist, Dr. Sanjay Bhojraj MD sits down with pharmacologist and genomic medicine specialist Dr. Tyler Panzner to unpack how your genes shape your response to diet, medications, and supplements.They explore the difference between genetics vs genomics, why one-size-fits-all nutrition advice (keto, carnivore, vegan) can be dangerous, and how polygenic risk scores and pathway-based genomics can guide truly precision nutrition and precision medicine. From vitamin D that never budges, to oxalate kidney stones, to why berberine may not be as “innocent” as Instagram says, this episode pulls back the curtain on the wild west of supplements.If you’ve ever wondered why your labs don’t change, why one cup of coffee wrecks you, or why your “clean” supplement stack makes you feel worse, this conversation is for you.Guest: Dr. Tyler PanznerDr. Tyler Panzner, PhD is a pharmacologist specializing in genomic medicine and supplement pharmacology. He helps individuals and clinicians use comprehensive genomic data to personalize diet, lifestyle, and supplementation—focusing on bottom-up molecular pathways rather than fear-based, top-down disease labels.Website: drtylerpanzner.comInstagram / TikTok / YouTube / LinkedIn: @DrTylerPanzner[00:00] Welcome to The Curious Cardiologist & Guest Intro Dr. Sanjay Bhojraj MD introduces pharmacologist and genomic medicine specialist Dr. Tyler Panzner.[01:20] VHS, Blockbuster & the Hallmarks of Aging (Fun Cold Open) Light banter on VHS, rewinding tapes, and joking about “hallmarks of aging.”[02:25] Genetics vs Genomics: What’s the Difference? Tyler explains genetics (single variants) vs genomics (your entire genetic “book”) and polygenic risk scores.[04:30] Why One-Size-Fits-All Diets Fail: Keto, Carnivore, Vegan & Your Genes How saturated fat response, ancestry, and LDL genetics change who thrives or crashes on keto/carnivore.[08:40] Oxalates, Kidney Stones & Carnivore as a Tool (Not a Religion) Oxalate...","thumbnail_url":"https://img.transistorcdn.com/ERjY_X6E6gwO4KLOBaOc5CRJbj_3VbOWBJACPcpnyaQ/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS8wZDcw/ODk2MmZhYmViMGVl/ODE2ZGVhMDgwYzJl/NTUyZS5wbmc.webp","thumbnail_width":300,"thumbnail_height":300}