{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"START","title":"🎧 START pod: Arvid Gollwitzer, Co-Founder, Anto Bio: “A Foundation Model for Microbial Communities”  ","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/3d82419a\"></iframe>","width":"100%","height":180,"duration":853,"description":"A drug was approved in China\nThen it failed clinical trials in the US\nNo one could figure out why\nThe answer was hiding in the gut microbiome\nAnto Bio’s model helped identify it\n99% of the genes in your body aren't yours \nThey belong to your microbiome\nOver two-thirds of drugs are heavily affected by how your gut processes them\nBut the microbiome data was too noisy. Too messy. Petabytes of it just sitting there\nAnto Bio's mission: make the gut microbiome computable for the first time\nThey're building foundation models that help pharma design drugs that work for more people\n🎙️ Arvid Gollwitzer, Co-Founder, Anto Bio on Fondo START pod\n1:18 What Anto Bio is building and why it's novel2:10 Why this didn't exist before3:05 99% of your genes aren't yours4:00 Why pharma ignoring the microbiome is a huge problem5:04 The microbiome is modifiable6:30 Modeling microbiome differences across populations7:00 Drug approved in China, failed in the US, and how Anto found out why8:02 How many drugs are affected by microbiome metabolism10:00 GLP-1s and the gut microbiome connection12:42 The biggest unsolved variable in drug development\nLearn more at www.anto.bio","thumbnail_url":"https://img.transistorcdn.com/q-E1hh7K6IS4AfZiNy2p4MYVGcUOO8lQP92h8QbOEOA/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS80NzVj/MDEzNjkxNjU1N2Uy/NDFhMDQ3M2ZhNWI3/NWY0MS5wbmc.webp","thumbnail_width":300,"thumbnail_height":300}