{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Thyroid Mystery Solved: Hashimoto's and Hypothyroidism Revealed","title":"108 The Case of Fatigue and Brain Fog Made Worse by B Vitamins","html":"","width":"100%","height":180,"duration":839,"description":"The Case:  Pam is dealing with brain fog, poor concentration, and fatigue. Tests revealed that she was low in Folate and Vitamin B12. Weeks of taking Vitamin B Complex didn’t help her symptoms at all. A little more research helped Pam understand that not all B vitamins are the same - some are synthetic while other options are natural and in methylated forms. Inspecting the B Complex vitamin she’d been taking, she discovered that the B12 was in the cyanocobalamin form and the folic acid was also synthetic. You might think the mystery was solved at this point, but after finding a methylated B Complex at the local health food store, and taking it for several weeks, her symptoms persisted. She increased her dosage, but after several weeks, she felt even worse.  Her labs showed that she was deficient in B vitamins, so why weren’t her supplements working?   The Investigation This is something I commonly see and while B vitamins are wonderful, they come in many forms but they are not ‘one size fits all.’ And there is another misconception - people believe that because B vitamins are water soluble, they can’t hurt anyone because the body will expel what it doesn’t use. This isn’t the whole story.    How Methylation Works The body has a process called methylation. This is a biochemical process where there is a transfer of four atoms - one carbon atom and three hydrogen atoms (CH3) from one substance to another. This process happens all the time, every second. When its optimal it has a significant positive impact on many biochemical reactions in the body that regulate all types of activities. Methylation is needed for neurotransmitter production, detoxification, histamine metabolism, estrogen metabolism, fat metabolism, cellular energy, eye health, and immune balancing. Essentially, if you think of the body as a machine, then methylation (and demethylation) are the gears that trigger the different systems in the body.  Two important methyl donors (nutrients that keep...","thumbnail_url":"https://img.transistorcdn.com/9ZbRr0xzgu8-YRnig2AcyeY_Nu_m2EBquTr83LV8K2g/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9zaG93/LzQ4NTg5LzE3MTE1/NjQxMDktYXJ0d29y/ay5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}