{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Ta de Clinicagem","title":"TdC 347: Cirrose descompensada - quando é ACLF?","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/4abb5e54\"></iframe>","width":"100%","height":180,"duration":1708,"description":"Nordman Wall e Flávio Barbieri convidam Carolina Mendes para discutir o conceito e manejo da insuficiência hepática crônica agudizada, do inglês Acute-on-Chronic Liver Failure (ACLF), quadro clínico que vai além da cirrose hepática descompensada, somando disfunções orgânicas e maior mortalidade.\nReferências:\nArroyo V, Moreau R, Jalan R. Acute-on-chronic liver failure. N Engl J Med. 2020;382(22):2137-45.\nRashed E, Soldera J. CLIF-SOFA and CLIF-C scores for the prognostication of acute-on-chronic liver failure and acute decompensation of cirrhosis: a systematic review. World J Hepatol. 2022;14(12):2025-43.\nEuropean Association for the Study of the Liver. EASL Clinical Practice Guidelines on acute-on-chronic liver failure. J Hepatol. 2023;79(2):461-91.\nKarvellas CJ, Bajaj JS, Kamath PS, et al. AASLD Practice Guidance on acute-on-chronic liver failure and the management of critically ill patients with cirrhosis. Hepatology. 2024;79(6):1463-502.\nArtzner T, Fernandez J, Jalan R. Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms. Intensive Care Med. 2023;49(6):689-91.\nPalliative care in the patient with acute-on-chronic liver failure. Clin Liver Dis (Hoboken). 2022;19(5):198-202.\nMezzano G, Juanola A, Cardenas A, et al. Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis. Gut. 2022;71(1):148-55.\nNagel M, Westphal R, Hilscher M, et al. Validation of the CLIF-C OF score and CLIF-C ACLF score to predict transplant-free survival in patients with liver cirrhosis and concomitant need for intensive care unit treatment. Medicina (Kaunas). 2023;59(5):866.\nHareesh GJ, Ramadoss R. Clinical profile, short-term prognostic accuracies of CLIF-C ACLF score and serial CLIF-C OF scores in acute-on-chronic liver failure patients: a prospective observational study. Indian J Crit Care Med. 2024;28(2):126-33.\nBelli LS, Duvoux C, Artzner T, et al. Liver transplantation for patients with...","thumbnail_url":"https://img.transistorcdn.com/lqcQlEC1m6aWV5CJqKTqNKKWbLXziZKK97FisF4ZuuE/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9lODM1/ZmI0ODIxZjAxM2U1/ZGUwMjhkYTYwNzZi/MGNmNi5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}