{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"萌喵读文献-肿瘤学","title":"今日肿瘤学最高分文献 - 2025-06-16","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/50e37e59\"></iframe>","width":"100%","height":180,"duration":105,"description":"欢迎收听科研喵播客，使用AI读文献，效率百倍，快来labcat.com.cn下载体验吧！最新研究揭示，MicroRNA-7（miR-7）是肿瘤糖酵解代谢的多面调节器。研究发现，miR-7通过直接靶向葡萄糖转运蛋白和糖酵解酶，抑制肿瘤细胞的葡萄糖摄取和糖酵解通量。此外，它还调节HIF-1α/ENO2轴和免疫检查点表达，重塑免疫抑制微环境，促进代谢与免疫的交叉对话。这些发现突出了miR-7在肿瘤代谢调控中的独特作用，并为其作为治疗靶点提供了新视角，为精准肿瘤学策略的发展提供了新思路。不要错过这一突破性进展，深入了解miR-7如何影响肿瘤代谢和免疫调控，尽在本期播客。","thumbnail_url":"https://img.transistorcdn.com/3WX36CzvFOrNjlF7WfWjzS4HdcMIMmzMs2bmPS-ejLU/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS83NDNm/MjQ1N2E5NjhjMzVj/NjM0ZTA3YzY2NDE2/ZmIyMi5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}