{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"萌喵读文献-生物信息学","title":"今日生物信息学最高分文献 - 2026-03-17","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/5b810c57\"></iframe>","width":"100%","height":180,"duration":184,"description":"科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。今天我们关注发表在《PLoS Medicine》(影响因子10.5)上的重要研究\"Circulating gut microbial metabolites and risk of coronary heart disease: A prospective multi-stage metabolomics study\"。这项多阶段代谢组学研究首次系统性地揭示了肠道微生物代谢物与冠心病风险之间的关联。科学家们通过分析五个前瞻性队列数据，确定了多种与冠心病显著相关的循环微生物代谢物，包括咪唑丙酸、3-羟基-2-乙基丙酸盐等。这一发现为肠道微生物在心血管疾病中的作用提供了新证据，为开发基于微生物代谢物的生物标志物和新型治疗方法开辟了新途径，有望改变冠心病的预防与治疗策略。","thumbnail_url":"https://img.transistorcdn.com/38WU46uKrju37cyiLrKcVSktFL4vxBb_oTgbpM_2CRw/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS8zOGU2/ZmEyYWE0MDZkNGFj/NWMzNGY5ZmU4YTk0/ZTBlNS5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}