{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Answers from the Lab","title":"NELL-1: Sanjeev Sethi, M.D., Ph.D.","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/6480687a\"></iframe>","width":"100%","height":180,"duration":1062,"description":"Sanjeev Sethi, M.D., Ph.D., explains Mayo Clinic Laboratories’ newly developed test to detect neural epidermal growth factor-like 1 protein (NELL-1), a biomarker for membranous nephropathy (MN). The immunohistochemistry assay examines tissue samples for NELL-1 antigen, which are found in 10% to 15% of MN patients. Discovered by Dr. Sethi in 2017, NELL-1 is the second most common antigen associated with MN and is correlated with underlying malignancy.","thumbnail_url":"https://img.transistorcdn.com/jhRCftFebxnTMwoIbA_WoqrSKwFRD_Y2kbh0JDjhx14/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9lYjNj/ZDc0NTE0MWNlOWRl/YzRiN2Q3NDg2Mjg5/YWE4MS5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}