{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"PACUPod: Critical Care","title":"Use of a drug-related problem oriented medical record in the medication review of critically ill patients Randomized clinical trial summary","html":"","width":"100%","height":180,"duration":605,"description":"Join PACULit as we unpack a randomized clinical trial evaluating a drug-related problem oriented medical record (DAM) used during medication reviews for critically ill patients. The study, conducted in two Brazilian ICUs, randomized 150 adults likely to require mechanical ventilation or with organ dysfunction to DAM-enabled medication review versus standard practice. Primary outcome was hospital length of stay; key secondary outcomes included in-hospital mortality and changes in SOFA scores. Results showed the DAM group with a shorter hospital stay (7.08 vs 10.70 days), markedly lower mortality (6.58% vs 25.68%), and a greater improvement in organ function (mean SOFA change −4.63 vs +1.88). The findings suggest that a structured, pharmacist-driven documentation tool can streamline identification and management of drug-related problems, enhancing multidisciplinary communication and potentially improving patient safety and outcomes. The discussion highlights implications for integrating DAM with electronic health records and decision support, the importance of training and institutional support, and considerations about generalizability given the study’s two-center setting. This episode synthesizes how structured medication review tools may advance ICU pharmacotherapy and reduce variability in care.","thumbnail_url":"https://img.transistorcdn.com/W5ppyJiVvpeq5HNrnsz_zaMmU5rmab3dOuTiTdwfeYQ/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9hMTdi/ZTcyYTUyYTdmMmY2/Y2VmYzc4ZmIwYzA4/NTdlMC5wbmc.webp","thumbnail_width":300,"thumbnail_height":300}