{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Intelligent Medicine with Dr. Ronald Hoffman | The Best of High Tech Medicine and Alternative Modalities","title":"Urolithin A: A Pathway to Enhanced Energy and Longevity, Part 1","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/6b24a32e\"></iframe>","width":"100%","height":180,"duration":1611,"description":"Urolithin A (Mitopure) and Mitochondrial Renewal--Muscle, Immune, and Skin Benefits: Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline details urolithin A and Timeline’s branded supplement Mitopure. She describes urolithin A’s discovery through pomegranate research and worm studies showing a 45% lifespan increase. She discusses human research including improved walking distance and clinical outcomes in muscle endurance and strength. Urolithin A is presented as supporting mitochondrial health by promoting mitophagy—recycling damaged mitochondria—distinct from other mitochondrial supports like CoQ10 and NAD precursors. They explain most people cannot produce enough urolithin A from foods because only 30–40% convert precursors via the microbiome and it would require about six cups of pomegranate juice daily. Dosing discussed is 500–1,000 mg/day via gummies, capsules, or powder, with effects developing over months. She reviews emerging research on immune aging, preclinical work on brain and neurodegenerative conditions, and topical urolithin A for skin.","thumbnail_url":"https://img.transistorcdn.com/VqZUkCahxIiAeF5-K8EvRI1GWNHpDBp8Xmmm6hLF4BU/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9lODBh/MjZiYjExYzcxZDZh/MmFmZTQ5ZTgzYTI3/Mzk1OS5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}