{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"萌喵读文献-肿瘤学","title":"今日肿瘤学最高分文献 - 2025-10-12","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/719f0ea0\"></iframe>","width":"100%","height":180,"duration":233,"description":"科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在Journal of nanobiotechnology(影响因子10.6)上的重要论文\"Lipid-based nanoparticles external triggered release strategies in cancer nanomedicine\"。研究指出，近半数人一生中将患癌症，而传统化疗药物面临递送挑战——不到0.1%的药物能到达肿瘤部位。脂质基纳米颗粒(LBNPs)虽能延长药物循环时间并利用EPR效应，但过于稳定的特性限制了药效释放。本文综述了热、超声、辐射、磁和光等外部触发策略的最新进展，这些技术可实现肿瘤部位的精准药物释放，大幅提高治疗效果并减少副作用，为癌症纳米医学开辟了新路径。","thumbnail_url":"https://img.transistorcdn.com/3WX36CzvFOrNjlF7WfWjzS4HdcMIMmzMs2bmPS-ejLU/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS83NDNm/MjQ1N2E5NjhjMzVj/NjM0ZTA3YzY2NDE2/ZmIyMi5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}