{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"START","title":"START pod: Jeff Liu, CEO & Co-Founder, FinalDose \"Programmable DNA drug destroying all cancers, unlocking 80% of targets\"","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/77daffff\"></iframe>","width":"100%","height":180,"duration":1075,"description":"Most cancer drugs target proteins\nFinalDose thinks the real opportunity is one layer deeper: DNA\nJeff Liu and his team are building a programmable drug platform that uses genetic mutations to identify and selectively destroy cancer cells\nCells without those mutations are not targeted\nInstead of creating a completely new drug for every cancer type, the platform is designed as a reusable system with different genetic instructions\nOne chassis.\nDifferent disease targets.\nThe broader bet: DNA is more deterministic than proteins, which could unlock therapeutic approaches traditional drugs struggle to reach\nSearch.\nDestroy.\n\"A programmable cell elimination platform.\"\n🎙️ Jeff Liu, Cofounder & CEO of FinalDose on START\n00:11 Why proteins may be the wrong layer for cancer treatment\n01:14 Using DNA mutations as programmable kill signatures\n03:20 Building a reusable therapeutic platform instead of one-off drugs\n05:00 Why hard biotech problems require interdisciplinary teams\n06:00 Getting into YC after a 4 a.m. interview in Japan\n08:00 Sam Altman’s $2M AI token offer — and why FinalDose passed\n10:08 How AI-native biotech is accelerating programmable medicine\n12:00 Why the future of medicine may look more like engineering\n13:05 The regulatory bottleneck for programmable therapeutics\nLearn more at finaldose.ai","thumbnail_url":"https://img.transistorcdn.com/q-E1hh7K6IS4AfZiNy2p4MYVGcUOO8lQP92h8QbOEOA/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS80NzVj/MDEzNjkxNjU1N2Uy/NDFhMDQ3M2ZhNWI3/NWY0MS5wbmc.webp","thumbnail_width":300,"thumbnail_height":300}