{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Hard Drugs","title":"Will AI solve medicine?","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/8fe3c96b\"></iframe>","width":"100%","height":180,"duration":16488,"description":"Artificial intelligence is transforming how we discover and develop new medicines. But how far can it really take us? In this episode, Jacob and Saloni trace the path of drug development from discovery to testing, manufacturing, and delivery. They explore where AI could speed things up, and where it still hits the limits of biology, data, and economics. They ask what it would take, beyond algorithms, to actually cure and eradicate diseases.\nHard Drugs is a new podcast from Works in Progress and Open Philanthropy about medical innovation presented by Saloni Dattani and Jacob Trefethen.\nYou can watch or listen on YouTube, Spotify, or Apple Podcasts.\nSaloni’s substack newsletter: https://www.scientificdiscovery.dev/\n\nJacob’s blog: https://blog.jacobtrefethen.com/ \nChapters:\n0:00:00 Intro\n0:09:56 Drug discovery\n1:02:20 Animal models\n1:49:09 Drug efficacy\n2:32:56 Drug safety\n2:58:29 Manufacturing and healthcare\n3:43:23 R&D funding\n4:00:56 Trust and ambition\n4:16:01 Summary\nBlogposts:\nClaus Wilke (2025) We still can’t predict much of anything in biology https://blog.genesmindsmachines.com/p/we-still-cant-predict-much-of-anything \nElliot Hershberg (2025) What are virtual cells? https://centuryofbio.com/p/virtual-cell \nJacob Trefethen (2025) Blog series. 1) What does AI progress mean for medical progress? https://blog.jacobtrefethen.com/ai-progress-medical-progress/ 2) AI will not suddenly lead to an Alzheimer’s cure https://blog.jacobtrefethen.com/ai-san-francisco/ 3) AI could help lead to an Alzheimer’s cure https://blog.jacobtrefethen.com/ai-optimism/ \nArticles:\nWendi Yan (2024) Discovering an antimalarial drug in Mao’s China https://www.asimov.press/p/antimalarial-drug \nJason Crawford (2020) Innovation is not linear https://worksinprogress.co/issue/innovation-is-not-linear/ \nShayla Love (2025) An ‘impossible’ disease outbreak in the Alps https://www.theatlantic.com/health/archive/2025/03/als-outbreak-montchavin-mystery/682096/ \nAlex Telford (2024) Origins of the lab...","thumbnail_url":"https://img.transistorcdn.com/bBbAA3-An3hw3uv_Sf647ZQV-IpESOooEROiyEp4Ytg/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS81MzM2/YTc5NmRlZGI2Zjhi/YWM2ZDk4MzBhZjg4/YTRjMi5wbmc.webp","thumbnail_width":300,"thumbnail_height":300}