{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Innovation to Impact: Drug Development, AI, and Regulatory Strategy","title":"Predictivity Is the New Currency of Drug Development","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/92b4575d\"></iframe>","width":"100%","height":180,"duration":1402,"description":"Drug development punishes optimism, and predictivity is one of the few defenses we have against translational risk. In this episode we connect translational science and regulatory science to a simple operating idea: treat attrition as data, not embarrassment. The tension is real. Do you want a model that explains the past beautifully, or one that helps you be less wrong before the next big spend? We unpack why “validation” after the fact is not enough, and how forecast accuracy, calibration, and honest miss rates should travel across programs instead of dying in slide decks. When predictivity is measured, learning becomes infrastructure. When it isn’t, failure stays expensive and repetitive. Takeaway: start tracking misses across your portfolio and make calibration a standing agenda item, not a post-mortem ritual.  If you liked this episode, steal the monthly cheat sheet at Innovation2Impact Newsletter (we do the digging, you keep the credit). ","thumbnail_url":"https://img.transistorcdn.com/Y1nZWqMkxS4Ee17tcD9y_wgj4JgHPHGNBpdmmK5mKz0/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS8wZTcz/OTlhZDEzZTZhODdi/ZDM5OGU2MTdiYWEx/YTBmNy5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}