{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Blood Cancer Talks","title":"Episode 69. ASH 2025 Lymphoma Roundup with Dr. Carla Casulo","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/97e98f98\"></iframe>","width":"100%","height":180,"duration":2659,"description":"BloodCancerTalks: ASH 2025 Lymphoma RoundupGuest: Dr. Carla Casulo, Associate Professor, Wilmot Cancer Centre, University of RochesterAbstracts DiscussedFollicular LymphomaEPCORE-FL1 (Falchi) - Epcoritamab plus lenalidomide-rituximab (R2) in relapsed/refractory FLTheme: Bispecific antibody combinations in R/R FL; comparing to other approaches Diffuse Large B-Cell Lymphoma (DLBCL) - Elderly/Unfit PatientsMorningSun (Sharman) - Mosunetuzumab monotherapy in patients ≥80 years or chemo-ineligibleEPCOR-DLBCL-3 (Vitolo) - Epcoritamab monotherapy in elderly patientsR-Pola-Glo - Rituximab-polatuzumab-glofitamab combination in older/frail patientsTheme: Single-agent and combination bispecific strategies for elderly and frail DLBCL patients DLBCL - First-Line TreatmentSMART STOP (Westin) - Chemotherapy-free approach using lenalidomide, tafasitamab, rituximab, acalabrutinib (ULTRA regimen)FrontMIND - Tafasitamab-lenalidomide added to R-CHOPTheme: Chemotherapy-sparing and chemo-intensification strategies in newly diagnosed DLBCL DLBCL - Relapsed/RefractoryDALY 2-EU (Borchmann) - Dual CD19/CD20 CAR-T (zamto-cel) versus R-GemOx in transplant-ineligible patientsTheme: Expanding CAR-T eligibility; treatment selection in transplant-ineligible R/R DLBCL Hodgkin LymphomaSWOG 1826 - 3-year update: Nivolumab-AVD versus brentuximab-AVDHD21 - 5-year update: PET-adapted BrECADD versus BEACOPPTheme: Long-term outcomes and treatment selection in newly diagnosed Hodgkin lymphoma Burkitt LymphomaZUMA-25 (Van Dorp) - Brexucabtagene autoleucel (Brexu-cel) in relapsed/refractory BurkittTheme: CAR-T therapy for the challenging population of R/R Burkitt lymphoma Mantle Cell Lymphoma - First-Line TrAVeRse - Acalabrutinib, venetoclax, rituximabGLOVe - Glofitamab, lenalidomide, venetoclax (high-risk MCL)BOVen - Zanubrutinib, obinutuzumab, venetoclax (older patients)MAVO - Acalabrutinib, venetoclax, obinutuzumabWindow-3 - Acalabrutinib-rituximab followed by brexu-cel (high-risk MCL)Theme:...","thumbnail_url":"https://img.transistorcdn.com/sqlYzk0Oxhchi1Lmft_9Md8dG97D7hyy2rwRG7COuc0/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9zaG93/LzMyMDc4LzE2NTcz/MTQxMDUtYXJ0d29y/ay5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}