{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"萌喵读文献-肿瘤学","title":"今日肿瘤学最高分文献 - 2025-09-21","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/991dfe80\"></iframe>","width":"100%","height":180,"duration":153,"description":"科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在《Journal of the American Academy of Dermatology》(IF:12.8)上的重要研究\"Impact of Immunosuppression on Cutaneous Squamous Cell Carcinoma Outcomes\"。这项涉及11,930名患者的国际多中心研究发现，免疫抑制不仅是皮肤鳞状细胞癌的危险因素，更是独立预测不良预后的关键指标。免疫抑制患者表现出更高风险肿瘤特征和更差疾病结局，包括局部复发、远处转移和疾病特异性死亡。研究特别指出，器官移植和慢性淋巴细胞白血病患者面临不同风险模式。这一发现为临床风险评估提供了重要依据，建议将免疫抑制状态纳入皮肤鳞状细胞癌的风险预测模型，以指导个体化治疗和随访策略。","thumbnail_url":"https://img.transistorcdn.com/3WX36CzvFOrNjlF7WfWjzS4HdcMIMmzMs2bmPS-ejLU/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS83NDNm/MjQ1N2E5NjhjMzVj/NjM0ZTA3YzY2NDE2/ZmIyMi5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}