{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Proteomics in Proximity","title":"When Proteins Tell Time: Biological Aging with Tony Wyss-Coray","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/a7be0523\"></iframe>","width":"100%","height":180,"duration":3194,"description":"Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources mentioned in this episode: UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date. https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies Research articles and newsUK Biobank Pharma Proteomics Project Full Cohort Study:  Thermo Fisher Scientific’s Olink Platform Selected for World’s Largest Human Proteome Studyhttps://ir.thermofisher.com/investors/news-events/news/news-details/2025/Thermo-Fisher-Scientifics-Olink-Platform-Selected-for-Worlds-Largest-Human-Proteome-Study/default.aspxParabiosis Conboy et al (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment.  Nature 433: 760-764. https://www.nature.com/articles/nature03260Villeda et al. (2011). The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 477, 90–94 https://doi.org/10.1038/nature10357Organ Aging/Ageing Clock Publications leveraging Olink ProteomicsOh, H.SH et al. (2025). Plasma proteomics links brain and immune system aging with healthspan and longevity. Nat Med 31, 2703–2711. https://doi.org/10.1038/s41591-025-03798-1Goeminne et al (2025). Plasma protein-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems Cell Metabolism, 37, 205-222.e6https://www.cell.com/cell-metabolism/fulltext/S1550-4131(24)00401-7Argentieri, M.A et al. (2024). Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations. Nat Med 30, 2450–2460. https://doi.org/10.1038/s41591-024-03164-7Young blood factors infused into young miceVilleda et al (2014). Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.  Nature Medicine.  20:659-663. https://www.nature.com/articles/nm.3569Single cell work...","thumbnail_url":"https://img.transistorcdn.com/ykdESoQYqhzogcyTRtlZ-HocZhd_d0QETSq8cMzg1DE/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9zaG93/LzM0MDk0LzE2NjMx/OTI3MzUtYXJ0d29y/ay5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}