{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Extrapolate with Rob Hof","title":"How We End Aging in 15 Years - Aubrey de Grey","html":"","width":"100%","height":180,"duration":3116,"description":"Biomedical gerontologist Aubrey de Grey breaks down why aging is a solvable engineering problem, not an inevitable destiny — and why he believes we are closer than ever to \"Longevity Escape Velocity.\"\n\nAubrey de Grey is an English author and biomedical gerontologist, best known for devising the SENS platform (Strategies for Engineered Negligible Senescence). He is currently the President of the LEV (Longevity Escape Velocity) Foundation. For decades, he has been the provocative face of the anti-aging movement, arguing that the human body is a machine with moving parts that can be repaired, and famously claiming that the first human to live to 1,000 is likely already alive.\n\nIn this episode, you get a deep dive into the mechanics of aging and the roadmap to defeating it. Aubrey moves past the hype to discuss the specific biological hurdles remaining, his current focus on \"Robust Mouse Rejuvenation,\" and the psychological barriers that stop humanity from treating aging with the urgency of a pandemic.\n\nHe explains, among other things: \n◼️ His definition of aging: why it’s simply the accumulation of damage from metabolism — like rust on a car — and why we don't need to understand metabolism perfectly to fix the damage \n◼️ Robust Mouse Rejuvenation: his current mission to double the remaining lifespan of middle-aged mice, and why this specific milestone will trigger a \"war on aging\" \n◼️ The timeline to immortality: why he estimates we are ~15 years away from \"Longevity Escape Velocity\" for humans, provided funding catches up \n◼️ The \"Pro-Aging Trance\": why people rationalize aging as a \"blessing\" or \"natural\" simply to protect themselves from the fear of getting their hopes up \n◼️ Why billionaires don't invest enough: the paradox where older billionaires think they are too old to benefit, and younger ones think they have plenty of time \n◼️ The limits of AI in biology: why he believes we still need \"wet labs\" and why simulations alone (even of single cells) can be...","thumbnail_url":"https://img.transistorcdn.com/uQRg1dVbp2nredhB-38LkoFxdAc79qEl8Xl62sIjRfw/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9iMGRj/YTZmMjY3Y2E4ZmQ0/M2YwNmI4YjE0ODJh/MjYzNi5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}