{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Intelligent Medicine with Dr. Ronald Hoffman | The Best of High Tech Medicine and Alternative Modalities","title":"The Science and Benefits of Nitric Oxide: The Swiss Army Knife Nutrient for Health, Part 1","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/b57d3ac8\"></iframe>","width":"100%","height":180,"duration":1556,"description":"Nitric Oxide: Supporting Vascular Health, Performance, and the Oral Microbiome with Dr. Nathan Bryan: Dr. Ronald Hoffman interviews nitric oxide researcher and entrepreneur Dr. Nathan Bryan about nitric oxide (NO) as a short-lived signaling gas that dilates blood vessels, reduces inflammation, mobilizes stem cells, supports mitochondria, and is linked to longevity. Bryan explains two NO production pathways: nitric oxide synthase from L-arginine and an entero-salivary nitrate pathway requiring dietary nitrate, specific oral bacteria, and stomach acid; he says sugar-heavy diets, fluoride toothpaste, antiseptic mouthwash, and proton pump inhibitors inhibit NO. Symptoms of deficiency include erectile dysfunction, rising blood pressure, metabolic disease/diabetes, exercise intolerance, and dementia/Alzheimer’s. They discuss limitations of many beet products, Bryan’s N-101 lozenges and NOBeats powder that generate NO, topical NO for wound healing and skincare, a fluoride-free prebiotic toothpaste, an upcoming mouth rinse, potential benefits for resistant hypertension, insulin resistance, cognition, and eye conditions like glaucoma, and access/discount details via hoffmannno.com.","thumbnail_url":"https://img.transistorcdn.com/VqZUkCahxIiAeF5-K8EvRI1GWNHpDBp8Xmmm6hLF4BU/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9lODBh/MjZiYjExYzcxZDZh/MmFmZTQ5ZTgzYTI3/Mzk1OS5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}