{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Thyroid Mystery Solved: Hashimoto's and Hypothyroidism Revealed","title":"137 Are You Ignoring an Important Connection Between Gluten, Your Gut, and Hashimoto's? with Vincent Pedre","html":"","width":"100%","height":180,"duration":3066,"description":"The Case:  Alison has Hypothyroidism and Hashimoto’s and also experiences tons of digestion issues.  She often feels gassy and bloated and has trouble going to the bathroom. She’s tried taking all types of probiotics, eating super nutritious fermented foods, and done several colon cleanses, but nothing helped.    The Investigation When I met Alison, she explained that she had taken gut-support vitamins and eaten a healthy diet. However, I could see right away that she was missing a few big clues in solving her health mystery.    Gluten, Gut Health, and Hashimoto’s I’ve talked a lot about the connection between Hashimoto’s and our gut on the podcast in the past. I knew that this was at the core of solving Alison’s issues. To discuss it further, I invited Dr. Vincent Pedre, aka America's Gut Doctor, to the show.  Dr. Pedre is an internist and the author of the upcoming book The Gutsmart Protocol.  One of the first things he brings up is the connection between Hashimoto’s and gut health as well as gluten. We’ve talked a lot about this connection on the Health Mysteries Solved podcast - including my own journey with Hashimoto’s and gluten. Dr. Pedre shared the work of Alessio Fasano, who studied the effects of gluten on the gut and how gluten can trigger autoimmunity. He discovered that gluten triggers the release of a protein called Zonulin, which increases gut permeability. This leads to leaky gut, which can eventually result in autoimmunity. Dr. Pedre also explained that there are three key factors in the development of autoimmune diseases: genetic predisposition, environmental triggers (such as gluten), and leaky gut. He went on to explain that one of the enzymes that helps break down gluten, called tissue transglutaminase, can create a chimeric molecule that can be recognized by the body's immune system as an invader. This can lead to an antibody response and cross-reactivity, especially with the thyroid where tissue transglutaminase is found in high...","thumbnail_url":"https://img.transistorcdn.com/9ZbRr0xzgu8-YRnig2AcyeY_Nu_m2EBquTr83LV8K2g/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9zaG93/LzQ4NTg5LzE3MTE1/NjQxMDktYXJ0d29y/ay5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}