{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"萌喵读文献-生物信息学","title":"今日生物信息学最高分文献 - 2025-11-27","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/d1eec999\"></iframe>","width":"100%","height":180,"duration":202,"description":"科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在影响因子高达12.5的《Ageing research reviews》上的重要论文：《The past, present, and future of adipose tissue browning and aging: a review combined with bibliometrics and bioinformatics of 2527 documents published over the past four decades》。这项研究揭示了脂肪组织褐变随年龄下降与代谢紊乱之间的恶性循环关系。通过对2527篇文献的计量分析，研究团队确定了PPARG、ADIPOQ和TG等关键基因，以及脂肪生成通路在衰老过程中的核心作用。这一发现为开发促进代谢健康衰老的新策略提供了重要方向，有望打破衰老与代谢疾病之间的恶性循环。","thumbnail_url":"https://img.transistorcdn.com/38WU46uKrju37cyiLrKcVSktFL4vxBb_oTgbpM_2CRw/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS8zOGU2/ZmEyYWE0MDZkNGFj/NWMzNGY5ZmU4YTk0/ZTBlNS5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}