{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"萌喵读文献-肿瘤学","title":"今日肿瘤学最高分文献 - 2025-10-14","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/e41351cd\"></iframe>","width":"100%","height":180,"duration":203,"description":"科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在Journal of nanobiotechnology(影响因子10.6)上的重要研究：\"Programmable metal-based immuno-photocatalytic nanoparticles for precision activation of anti-tumor immunity\"。这项突破性研究开发了一种新型纳米平台，通过整合光疗与免疫调节，时空特异性地激活抗肿瘤免疫。这些智能纳米颗粒能产生活性氧，刺激免疫原性细胞死亡，同时递送免疫检查点抑制剂和佐剂，重塑肿瘤微环境。临床前模型显示它们显著抑制肿瘤生长，激活免疫系统并预防转移，且全身毒性极低。这项技术为治疗免疫抵抗性肿瘤提供了全新思路，有望实现精准、微创的个性化癌症免疫治疗，代表了纳米医学在肿瘤治疗领域的重大进展。","thumbnail_url":"https://img.transistorcdn.com/3WX36CzvFOrNjlF7WfWjzS4HdcMIMmzMs2bmPS-ejLU/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS83NDNm/MjQ1N2E5NjhjMzVj/NjM0ZTA3YzY2NDE2/ZmIyMi5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}