{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"HealthTech Remedy","title":"Decentralized Clinical Trials: The Science 37 Story with CMO Dr. Jonathan Cotliar","html":"","width":"100%","height":180,"duration":2969,"description":"Is the current clinical trial system fundamentally broken? With an estimated 95% of cancer patients unable to participate in clinical research, a new model is urgently needed. This episode dives deep into the world of Decentralized Clinical Trials (DCTs), a revolutionary approach that brings research directly to patients, breaking down long-standing barriers of geography, cost, and convenience. We explore how this model could fix a system that often fails the very people it's meant to serve.\nJoined by our special guest, Dr. Jonathan Cotliar, Chief Medical Officer of Science 37, we uncover how technology is making research more accessible and equitable. We dissect the immense challenges of traditional trials, discussing the incredible burden placed on patients and how this leads to a staggering lack of clinical trial diversity. You'll learn about the innovative solutions that are changing the game, from remote data collection using wearable sensors to virtual study visits. We trace the fascinating journey of Science 37, a pioneer in the DCT space, from its founding in 2014, through its meteoric rise during the pandemic and a $1.3 billion SPAC merger, to its current operations. The discussion also tackles the significant hurdles to adoption, including industry inertia and the critical role of evolving FDA guidance on clinical trials. Dr. Cotliar shares his firsthand experience navigating regulatory skepticism and convincing multi-billion dollar pharma companies to embrace this new frontier. A key focus of our conversation is the transformation of clinical trial patient recruitment, moving from a site-centric model to direct-to-patient outreach through digital channels and patient advocacy groups, especially for rare diseases. Discover the key benefits of decentralized trials and what the future holds for drug development and patient care.\nAbout Our Guest:\nDr. Jonathan Cotliar is the Chief Medical Officer at Science 37. A former academic clinician trained at UCLA as...","thumbnail_url":"https://img.transistorcdn.com/Al9s4QJpRCg2VJ2YaV_fo3tDCayXbUO7NTDbnFeSAUQ/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9mNTVk/OTAwMzQxYWFiZmYy/ZWFlNzFmN2RmOTcx/MDMwNy5wbmc.webp","thumbnail_width":300,"thumbnail_height":300}