{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"Thyroid Mystery Solved: Hashimoto's and Hypothyroidism Revealed","title":"130 Got a Mysterious Chronic Condition? It Might be Mast Cell Activation Syndrome with Guest Beth O'Hara","html":"","width":"100%","height":180,"duration":3033,"description":"The Case:  Julie has digestive issues, headaches, lots of skin rashes and irritation, brain fog, and fatigue She is also very sensitive to environmental triggers like fragrances, smoke, and chemicals.   She eats and lives as clean as possible but nothing seems to help.  She’s seen a dozen doctors who have prescribed a variety of medications but nothing helped.  It’s so common for conventional doctors to focus on treating the symptoms as if they are unrelated instead of considering what the collection of symptoms might mean. Julie knew that her symptoms had to be connected which is when she reached out to me. My feeling was that this was a systemic issue and we got to work investigating the root cause of her problems.  The Investigation With my suspicions of a systemic issue, I knew that Beth O’Hara would be a great source of information. She’s been on Health Mysteries Solved before to speak about Oxalates (episode 67) and Histamines (episode 81). This time, I wanted to dive into the topic of Mast Cells and Mast Cell Activation Syndrome which is Beth’s expertise. What are Mast Cells? Mast cells are one of the most important types of immune cells in our bodies. They're present at every interface between our bodies and the outside world, and they're also found in every single tissue except for the retina. So, if we think about that, they're in the skin, in the lining of the sinus passages, in the digestive tract from the mouth to the stomach, and they're also found in muscles and bones. They migrate to very important areas like nerve endings and the brain's limbic system. Mast cells are responsible for a number of functions ranging from the sleep-wake cycle to pregnancy and wound healing. They also help the body monitor for whether or not we're safe from things like toxins, mold, candida, pathogens, parasites, viruses and bacteria. They even monitor for co-infections (like lyme disease). Mast cells are also looking for all types of stressors including...","thumbnail_url":"https://img.transistorcdn.com/9ZbRr0xzgu8-YRnig2AcyeY_Nu_m2EBquTr83LV8K2g/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9zaG93/LzQ4NTg5LzE3MTE1/NjQxMDktYXJ0d29y/ay5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}