{"type":"rich","version":"1.0","provider_name":"Transistor","provider_url":"https://transistor.fm","author_name":"萌喵读文献-肿瘤学","title":"今日肿瘤学最高分文献 - 2025-06-21","html":"<iframe width=\"100%\" height=\"180\" frameborder=\"no\" scrolling=\"no\" seamless src=\"https://share.transistor.fm/e/f8a6480f\"></iframe>","width":"100%","height":180,"duration":88,"description":"科研喵使用AI读文献，祝你效率百倍，访问LabCat.com.cn下载。最新研究发现，CAR-T细胞疗法在血液肿瘤治疗中取得了显著成效，但传统病毒转导技术存在插入突变风险。一项发表在《分子医学趋势》杂志的研究，由Xiao Y团队领衔，探讨了一种新兴的非病毒基因工程技术，利用mRNA和脂质纳米颗粒（LNPs）进行CAR工程，以提高细胞疗法的安全性和可负担性。这项技术不仅有望为癌症治疗带来突破，还可能应用于非癌症疾病的免疫疗法，预示着未来个体化免疫治疗的新方向。","thumbnail_url":"https://img.transistorcdn.com/3WX36CzvFOrNjlF7WfWjzS4HdcMIMmzMs2bmPS-ejLU/rs:fill:0:0:1/w:400/h:400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS83NDNm/MjQ1N2E5NjhjMzVj/NjM0ZTA3YzY2NDE2/ZmIyMi5qcGc.webp","thumbnail_width":300,"thumbnail_height":300}