How Ketamine is Rewriting the Biology of Depression

What if the traditional view of depression—a simple imbalance of serotonin—was wrong? In this episode of Learning and Living STEM in Connecticut, host Tanimu Deleon talks with Dr. John Krystal, Chair of Psychiatry at Yale and recipient of the 2026 Connecticut Medal of Technology, to discuss his groundbreaking discovery of ketamine's rapid antidepressant effects and how it changed our understanding of depression's biology.

What is Learning & Living STEMM in Connecticut?

The Academy is a nonprofit created by a special act of the Connecticut General Assembly in 1976, with key areas of work including advising and informing the people and the state of Connecticut on science, technology, engineering, mathematics, and medicine (collectively known as STEMM).

This podcast is key to sharing with the residents of our state interesting STEMM developments and increasing visibility for the state’s innovators and entrepreneurs, businesses and industries, academics, our talented workforce, and those doing STEMM-related work in public service.