Blood Cancer Talks

In this episode, we dive into the data on maintenance therapy in multiple myeloma with Dr. Hira Mian and Dr. Manni Mohyuddin. Here are the key studies we discussed:

1. Meta-analysis of individual patient-level data from CALGB, IFM, and Italian maintenance RCTs (lenalidomide vs placebo or observation):
2. Myeloma XI RCT (lenalidomide vs observation):
3. Outcomes of lenalidomide maintenance stratified by cytogenetic subgroups (Secondary analysis of Myeloma XI):
4. Canadian real-world data on lenalidomide maintenance:
5. FORTE trial (Carfilzomib-Lenalidomide vs Lenalidomide):
6. ATLAS trial (Carfilzomib-Lenalidomide-Dexamethasone vs Lenalidomide):
7. Differential censoring and potential impact on PFS in ATLAS trial:
8. GEM2014 (Ixazomib-Lenalidomide-Dexamethasone vs Lenalidomide-Dexamethasone):
9. MASTER trial (MRD-guided treatment de-escalation):
10. Outcomes after MRD-guided treatment discontinuation (Secondary analysis of GEM2014MAIN trial):

What is Blood Cancer Talks?

This is a podcast on latest advances in the understanding and management of blood cancers. Here, we will bring a wide range of experts within hematologic malignancies to discuss various topics in depth.
Host: Raj Chakraborty, MD from Columbia University, New York, Ashwin Kishtagari, MD, from Vanderbilt University, Nashville, and Edward Cliff, MD, from Harvard University, Boston
Tweet your suggestions and feedback to @rajshekharucms @AshKishtagari @Eddie_Cliff @BloodCancerTalk