Mayo Clinic Q&A

On the Mayo Clinic Q&A podcast, Dr. Joaquin Sanchez-Sotelo, a Mayo Clinic orthopedic surgeon, discusses advances in shoulder replacement surgery, including custom-fitted implants.

Show Notes

Shoulder replacement surgery is done to relieve pain and other symptoms that result from damage to the shoulder joint. Common conditions that can damage the shoulder joint include osteoarthritis, rotator cuff injuriesand fractures, among others. 

Thanks to improved surgical techniques and an aging population, the number of shoulder replacement surgeries is increasing.

"The rate of usage of shoulder replacement in the United States has increased dramatically," explains Dr. Joaquin Sanchez-Sotelo, a Mayo Clinic orthopedic surgeon. "And I think there are two reasons. One is that implants are better. And also, that patients now are more active with their upper extremities later in life. So, they need the procedure because they want to have a life where they can enjoy activities pain-free."

Traditionally, shoulder replacement removes damaged areas of bone and replaces them with standard parts made of metal and plastic. Joint replacement surgery could be a challenge if some of the bone is missing, the bone quality is poor, or if a bone graft is not accurate. 

Now, thanks to new technology, there is another option. Using CT scans and 3D-printed models, some patients can receive joint replacements that are created to be custom fit to their anatomy. 

"The benefit is you are guaranteeing the patient that the implant is going to fit his or her shoulder, No. 1," says Dr. Sanchez-Sotelo. "No 2., it decreases surgical time tremendously. Because in the past, you had to get exposure and then prepare the bone until it fits one of the off-the-shelf implants. Now you know that the implant is going to fit the patient right out of the box. So surgery time is less." 

There are some limitations to use of the new implants. People with severe deformities may not be candidates, and people who require surgery quickly may not have time to wait for a custom implant to be built. 

Despite these limitations, Dr. Sanchez-Sotelo says, like artificial intelligence and mixed reality, custom-fitted joints could be another game-changer in orthopedics and another tool for surgeons to help patients.

"I think this is going to transform our practice," says Dr. Sanchez-Sotelo. "Technology is advancing so fast in medicine and orthopedic surgery. I'm just excited to see how we can change the operation, make it faster, make it easier, and lead to a much better outcome."

On the Mayo Clinic Q&A podcast, Dr. Joaquin Sanchez-Sotelo, discusses advances in shoulder replacement surgery, including custom-fitted implants.

The custom-fitted shoulder implant discussed in this podcast is produced by Strkyer. Dr. Sanchez-Sotelo and Mayo Clinic receive consulting fees and royalty payments from Stryker for shoulder arthroplasty products; however, Dr. Sanchez-Sotelo and Mayo Clinic do not have any relevant financial conflicts with this specific device.

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Mayo Clinic Q&A

Narrator: Coming up on Mayo
Clinic Q&A, a look at custom-fit

shoulder replacement.

Dr. Joaquin Sanchez-Sotelo: Another
is this fascinating technology

where you can tell a computer
program where is it that you

want your implant planned. For
orthopedics, it is very

important that the implant lands
exactly in that location. And

then with 3D technology, you can
create a metallic envelope that

will fill in the defects that
are present in the bone.

Narrator: Shoulder replacement
is one of the most successful

orthopedic surgical procedures
today. And Mayo Clinic surgeons

are using cutting-edge software
to create a shoulder joint that

precisely fits the patient.

Dr. Joaquin Sanchez-Sotelo: And
then as a surgeon, you plan the

surgery virtually and decide for
that patient, where is it that

you want the component to land.
The benefits are, as I said, you

are guaranteeing the patient
that the implant is goiong to

fit his or her shoulder, number
one. Number two, it decreases

the surgical time tremendously.

Dr. Halena Gazelka: Welcome,
everyone to Mayo Clinic Q&A. I'm

your host Dr. Halena Gazelka.
Shoulder replacement surgery is

done to relieve pain and other
symptoms that result from damage

to the shoulder joint.
Traditionally, shoulder

replacement removes damaged
areas of bone and replaces them

with standard parts made of
metal and plastic. Thanks to new

technology, there's another
option. Using CT scans and 3D

modeling, patients can now
receive joint replacements that

are custom fit to their anatomy.
With me today to discuss this is

Mayo Clinic orthopedic surgeon,
Dr. Joaquin Sanchez-Sotelo.

Thanks for being here today,
Joaquin.

Dr. Joaquin Sanchez-Sotelo: Of
course, Halena. Thank you for

having me.

Dr. Halena Gazelka: I think this
is just fascinating. And I can't

wait to hear the benefits of
this for patients, which I'm

sure are numerous. But first,
can you tell us how common is it

to have to replace someone's
shoulder joint? And who do you

do it for?

Dr. Joaquin Sanchez-Sotelo: That
is a great question, Halena. So

the rate of usage of shoulder
replacement in the United States

has increased dramatically. And
I think there are two reasons.

One, is that implants are
better. And also that patients

now are more active with their
upper extremities later in life.

So they need the procedure
because they want to have a life

where they can enjoy activities
pain free. So currently, there

are more than 100,000
arthroplasties of the shoulder

done in the United States every
year. And the projection is that

by 2025, there will be 250,000
replacements every year. So

very, very common. You were
asking what are the most common

reasons. So to be honest, the
most common are two of them. One

is what we call plain
osteoarthritis, where in a ball

and socket joint like the
shoulder, the cartilage of the

joint disintegrates. And that
leaves the raw bone exposed, and

that's painful. So that's one
very common indication. A

second, is actually patients
that have a long-standing tear

of their rotator cuff. And then
the joint degenerates secondary

we call that cuff tear
arthropathy. Of course, there

are other reasons, maybe a
fracture sometimes or congenital

disease, but the two most common
will be primary osteoarthritis

and cuff tear arthropathy.

Dr. Halena Gazelka: So during
the intro, I mentioned that

traditional joint replacement
has involved taking something

that is metal and plastic
essentially, made in a factory,

not specific to someone but made
in sizes, and then you replace

the shoulder joint. So what are
the benefits and disadvantages

of traditional methods of
replacing shoulders?

Dr. Joaquin Sanchez-Sotelo: Yeah,
so one issue that we have in the

shoulder in particular is that,
as I said, this is a ball and

socket joint, the socket, that
is called the glenoid, is

actually very small in humans.
So for people that can see the

image if you're not just
listening, I'm showing a model

of the scapula, which is a very
interesting bone. And the socket

of the shoulder is at the corner
of the scapula. And it's already

a small bone to begin with, It
is tiny. And not uncommonly,

this bone is actually deformed
when someone needs a

replacement. So I have another
model that you may compare to

the one I showed and not sure if
you can see it very well in the

screen, but this particular
scapula, glenoid, has been

missing on the back as opposed
to a normal glenoid. So

traditionally, when we had to
fit a component in the socket,

the only way to do it, is as you
said, take an off-the-shelf

implant, and then remove more
bone to adapt it. And the

downside of that is that you're
already working on a small bone

that already has bone loss, and
then you remove more bone to

place the implant. So then the
implant is now a very deep

portion of the joint, which
mechanical is not ideal. And if

that were to fail, you as a
surgeon have already removed all

the bone. So now there is this
fascinating technology where you

can tell a computer program
where is it that you want your

implant to land. For
orthopedics, it is very

important that the implant lands
exactly in that location. And

then we 3D technology you can
create a metallic envelope it is

called, that will fill in the
defects that are present in the

bone. So, for example, this is
one such component, this is

called the baseplate component
of a reversal prosthesis. And

the part that we know want to
land somewhere is the metallic,

more shiny part, right?
Traditionally, these have a flat

back, so you basically rim the
bone and place them. But now

what you can do is you can place
the components virtually in a

computer program, whatever you
think it has to be, hit a

button, and then the computer
will calculate this form of

metal. And it's interesting
because human bone grows very

well into titanium. And then the
company will send you a model.

So, this will be the scapula
adaptation that you can confirm

that is going to fit perfectly
in this patient. So you can see

how you will have perfect fit.
And they come up with a guide

you can use in the operating
room for the component. That's

exactly where, where you want it
to land. And I must disclose

that I help Stryker Corporation
with implant design forMayo

Clinic, even though I didn't
help with this particular

design, but that's important for
the listeners to know about our

potential conflict of interest.

Dr. Halena Gazelka: That's
absolutely fascinating. And I

could see there must be
significant advantages, how long

has this been available?

Dr. Joaquin Sanchez-Sotelo: So
it was released to the market,

actually this year. So it's
completely brand new technology

that I think is going to
transform our practice. But the

benefits are, as I said, You are
guaranteeing the patient that

the implant is gonna fit his or
her shoulder, number one. Number

two, it decreases surgical time
tremendously. Because in the

past, you had to get exposure
and then prepare the bone until

it fits one of the parts that
are on the shelves. Now you know

that the part you are getting is
gonna fit that patient's

anatomy. So you basically open
the box, get that plugged in and

place it, we're basically done.
So surgery time is less. And

it's also very cost-effective
for hospitals, because then you

have only one component per
patient, as opposed to having a

lot of them on the shelf.

Dr. Halena Gazelka: Well, that's
really interesting. So, the

surgical time is less, but I
would imagine there must be some

prep time ahead, and what's the
process that you go through to

develop a custom joint for a
patient?

Dr. Joaquin Sanchez-Sotelo: So
for this particular system,

typically the surgeon will plan
the case. So you get the CT scan

of the patient, it comes from
something called DICOM files

that you can upload in the
software. And then as a surgeon,

you plan the surgery virtually,
and decide for that patient,

where is it that you want the
component to land, and that

takes about 5 to 10 minutes
approximately, Then you hit the

button that gets the metal
envelope, and the component is

shipped to the hospital within
typically one month. You have to

plan the surgery at least a
month in advance. But the prep

time on the side of the surgeon
is actually maybe 10 to 15

minutes, so it's not that much.
And then when the day of surgery

occurs, you basically get
exposure, you have to drill the

bone to get this back on the
post. But everything else all

the irregular bone that the
patient may have, is perfectly

matched to the irregular surface
of titanium that the company

made for that patient.

Dr. Halena Gazelka: Wow. So I
think some of the benefits are

obvious. And you mentioned them.
Are there any disadvantages to

this type of joint replacement?

Dr. Joaquin Sanchez-Sotelo: Yeah,
so the two main ones will be

that if for whatever reason, the
implant gets damaged or

contaminated in the operating
room, you can't use it, right?

Because they only ship one. So
as a surgeon, you have to be

careful because if for whatever
reason it gets damaged or maybe

contaminated, including
infection, you have to go back

to the regular replacement,
which is not a big deal. And

then the second, is that as you
probably know, in health care,

every single adjustment comes
with a premium financially. So

this component is slightly more
expensive than the official one,

but not by much.

Dr. Halena Gazelka: So I imagine
you still, at times, do a

traditional joint replacement.
And how do you decide if someone

is a candidate to have a custom
joint replacement versus using a

traditional method?

Dr. Joaquin Sanchez-Sotelo: Yeah,
the main limitation of the

custom made prosthesis is that
the thickness of the envelope

that was approved by the Food
and Drug Administration is

limited. Because as you know, in
North America, the FDA is very

careful about only launching
implants are for sure going to

work. So they didn't have enough
testing to be able to create an

envelope that will be very, very
large. I'm talking about 2,3,4

centimeters. So for people with
really severe deformity, this

implant cannot be built. So
there are patients that come

with so much bone missing that
the only way to reconstruct that

shoulder is to use bone graft,
typically from the waistline

like iliac crest or other
locations. And then the second

limitation can be cost and time.
So, if someone really wants to

have the operation the day after
he or she seen in consultation,

of course, you don't have that
month of leeway. And you need

the CT scan, which is radiation.
But today, I will argue that the

majority of shoulder
arthroplasties, in the United

States are done, always, with a
CT scan is part of our routine

right now. So that doesn't
change much the workflow fo the

patient or the surgeon.

Dr. Halena Gazelka: Well, that's
just fascinating. I'm curious

how widespread this is, Joaquin.
Is it available in most

orthopedic practices or only at
large medical centers?

Dr. Joaquin Sanchez-Sotelo: So
this is just starting. And I

think, as with everything else,
we just have to be confident

that new technology really helps
our patients. But my prediction

is that this is going to
continue to expand. Right now

there is only one company making
these for the primary

applications. There are other
companies making it for more

custom applications, for very
complex deformities. I think we

will expand. But one of the
beauties of the podcast you run

is that it brings to the
patients or prospective patients

an idea of how quickly
technology is moving and what

new things are coming out that
have truly potential to improve

patient outcomes.

Dr. Halena Gazelka: Joaquin, I'm
really curious, is custom joint

replacement, something that's
also being developed for other

joints or the shoulders unique
in some way that you need this?

Dr. Joaquin Sanchez-Sotelo: No,
in fact, this initially started

in knee replacement, actually.
There was one company that

basically was created to develop
custom made implants for knee

arthroplasty. And that, to some
extent, has not been used very

commonly in the knee because in
knee replacement, there is a lot

of use of robotic surgery, which
is not present in the shoulder.

But also, the bones in the knees
are bigger, so you have more

freedom as a surgeon to maybe
remove some more here and there

and still fit the implant. The
challenge with the shoulder is

that the socket of the shoulder
is so small, that is really

beneficial to not remove any
bone, period. So if you can

basically build up the missing
bone with metallic augment, it

is much more superior in the
shoulder than removing bone so

you can fit an off-the-shelf
implant.

Dr. Halena Gazelka: We talked
about how the surgical time is

decreased by using a custom
implant. And I'm also wondering

about the recovery. Because I'm
thinking about some of my older

patients in the pain clinic who
really are extremely limited.

They can't use a walker because
they have shoulder issues and

mobility is a real issue. How is
the recovery for this?

Dr. Joaquin Sanchez-Sotelo: Yeah,
the recovery in general, for

shoulder replacement — this has
nothing to do with patient

matched implants — I'm talking
about in general, has improved

tremendously. And to the credit
of your specialty, it is mostly

because of anesthesiologists and
pain doctors. So, when I was a

fellow, shoulder surgery was
perceived to be one of the most

painful experiences that one can
go through in orthopedics. And

now, thanks to the advances that
you and people in your field

have done with peripheral nerve
blocks, it's incredible to me

that most patients tell me, you
know, I had no pain in surgery.

As you know, we offer patients a
block before surgery. And you

know this better than I do. But
that concept of preemptive

analgesia really works, meaning
that when the block has been

done, as you know better than I
do, the brain really doesn't

know that there was an operation
done because the feeling was

blocked. So the thymus doesn't
get sensitized, I don't think.

And patients have a very
pain-free experience. And the

other thing that comes as a
question in my clinic all the

time is people are older
75,80,82, 85 that already

disabled. Provided they are
reasonably healthy, we have

three studies from our practice
that showed that the recovery

and complication rate is
identical to younger patients.

So we no longer consider
advanced age a contraindication

for surgery, provided the
patient is healthy enough. And

there are some people that,
without replacement of the

shoulder, they will have to move
in with a family member or go to

a nursing home. Whereas if they
have the shoulder replacement,

they can function, they can
actually leave a home and enjoy

a more independent life.

Dr. Halena Gazelka: What
wonderful work you are doing.

Thank you, Joaquin. Any last
words you'd like to share with

our audience today?

Dr. Joaquin Sanchez-Sotelo: Well,
I just want to highlight how

beneficial this operation can be
for patients that really need

it. And also to stay tuned
because technology is advancing

so fast. You know, we have now
electric cars, and smartphones,

and I Watches this and things
that have really changed in the

way we handle technology and
that's transpiring into medicine

or orthopedic surgery. So I'm
just excited to see how many

more things are coming out. That
can really, really change the

outcome of the operation, make
it faster, make it easier, and

lead to a much better outcome.

Dr. Halena Gazelka: It is so
exciting to learn all of the new

developments in medicine going
on. Thank you for being here to

share them today, Joaquin.

Dr. Joaquin Sanchez-Sotelo: Thank
you for having me. It's always

wonderful to talk to you.

Dr. Halena Gazelka: Our thanks
to Mayo Clinic orthopedic

surgeon, Dr. Joaquin
Sanchez-Sotelo, for being here

today to talk to us about custom
shoulder joint replacement. I

hope that you'll learned,
something. I know that I did. We

wish each of you a wonderful
day.

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