Future of Life Institute Podcast

Paul-Enguerrand Fady is a Senior Biosecurity Policy Manager at the Centre for Long-Term Resilience. He joins the podcast to discuss how AI is changing biosecurity. We cover how new tools could help defenders develop vaccines and diagnostics while also lowering barriers to misuse, and how managed access, know-your-customer checks, and DNA synthesis screening can reduce risk. The conversation also examines mirror life, medical supply chains, stockpiles, and why governments should plan ahead of crises.



LINKS:



CHAPTERS:

(00:00) Episode Preview

(01:11) Offense-defense balance basics

(11:13) Defensive AI opportunities

(19:24) Model release and evals

(25:59) DNA synthesis screening

(36:14) Screening incentives and infohazards

(46:36) Liability and mandates

(52:37) Mirror life risks

(01:03:28) Persistence and incentives

(01:10:18) Mirror life governance

(01:20:42) Supply chain lessons

(01:30:11) Stockpiling medical countermeasures

(01:37:58) Reshoring critical supplies



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What is Future of Life Institute Podcast?

The Future of Life Institute (FLI) is a nonprofit working to reduce global catastrophic and existential risk from powerful technologies. In particular, FLI focuses on risks from artificial intelligence (AI), biotechnology, nuclear weapons and climate change. The Institute's work is made up of three main strands: grantmaking for risk reduction, educational outreach, and advocacy within the United Nations, US government and European Union institutions. FLI has become one of the world's leading voices on the governance of AI having created one of the earliest and most influential sets of governance principles: the Asilomar AI Principles.