In this episode, I sit down with Dr. Elizabeth Yurth, MD, ABPMR, ABAARM, FAARM, FAARFM, FSSRP. renowned as one of the brightest minds in regenerative and longevity medicine. We discuss the concept of “biohacker syndrome,” exploring why more supplements aren’t always better, as well as diving into cutting-edge therapies like GLP-1 agonists and rapamycin. Dr. Yurth unpacks the myths around cholesterol and NAD, clarifies the hype on biological age tests, and shares how bone health is often overlooked yet essential to long-term vitality. Throughout our conversation, she emphasizes that true longevity relies on balancing the right interventions, not just piling them on.
We also talk about the critical interplay between muscle and bone: why osteoporosis and sarcopenia go hand in hand, and how resistance training remains a cornerstone of healthy aging. From exploring repurposed drugs (like Telmisartan and Cialis) for broader health benefits to understanding why low-dose NAD or antioxidants might be better than high-dose regimens, Dr. Yurth’s insights reflect her deep research background. If you’re looking to sift through the confusion of trendy protocols and focus on science-backed, personalized approaches, this conversation is for you.
#EsraÇavuşoğlu #AyıkKafa #ElevatingLifeEvolvingHealth #Longevilab #DrElizabethYurth #Biohacking #boulderlongevityinstitute
Dr. Elizabeth Yurth:
Website:
https://boulderlongevity.com/about/dr-elizabeth-yurth/
Instagram: https://www.instagram.com/dryurth?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==
00:00-
05:29 Introduction
05:29-
09:05 “Biohacker Syndrome” Dr. Yurth explains why piling on endless supplements can be counterproductive.
09:05-
10:55 From orthopedics to longevity. Her decision to pursue new training in longevity and integrative regenerative medicine.
10:55-
12:41 Research and staying up-to-date. How Dr. Yurth keeps current with cutting-edge findings (daily paper reviews, global physician chats). The challenge of separating genuine research from industry-driven agendas.
12:41-
15:55 Future of longevity and adaptability. Prospects for living to 120 and beyond.
15:55-
18:05 Yamanaka Factors, AI and senolytics. Why total cellular reset may not always be beneficial, and how AI can help.
18:05-
20:15 Biological age tests and limitations. Why DNA methylation clocks aren’t yet reliable gold standards. The complexities of measuring true cellular age vs. chronological age.
20:15-
25:09 Longevity myths: Telomeres and over-supplementation. Telomeres as only a small part of the puzzle.
25:09-
28:36 Risks of excessive antioxidant use and blocking necessary oxidative stress.
28:36-
36:06 Importance of bone health and osteoporosis.
36:06-
42:17 The problem with constant high-dose NAD. Better strategy is to control CD38 and NNMT enzymes.
42:17-
49:09 GLP-1 Agonists for more than weight loss: Protective effects on heart, brain, immune system, and systemic inflammation.
49:09-
55:05 Re-examining cholesterol myths. Importance of particle size and ApoB/ApoA ratios rather than just lowering LDL.
55:05-
01:02:55 Repurposed drugs for longevity: Rapamycin, Metformin, Telmisartan, Tadalafil and Naltrexone.
01:02:55-
01:06:15 Exercise: The ultimate tools. How regular resistance training and daily movement outperform any single drug.
01:06:15-
01:08:15 Glutathione IV vs. Precursors.
01:08:15-
01:10:22 Conclusion
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*Dr. Esra Çavuşoğlu, PhD*
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*About Ayık Kafa*
Dr. Esra Çavuşoğlu, PhD, took her studies, starting from her personal treatment experiences and continuing with her clinical psychology education, to the next level by completing her PhD focused on Addiction. Dr. Esra in Ayık Kafa podcast discusses the world’s latest technologies, protocols, products and research in the fields of Biohacking and Longevity, while sharing first-hand information and experiences about the Disease of Addiction, as well as her latest academic studies.
*About Dr. Esra Çavuşoğlu, PhD*
Longevilab's founder, Dr. Esra, is a United States and internationally trained clinical psychologist and a certified addiction therapist in New York. She served as International Development Advisor on the Yale University Faculty of Medicine Clinical Advisory Board. She is the founder and supervisor of Gaziantep Oya Bahadır Yüksel Rehabilitation Center, Dr. Esra is the designer and implementer of the Turkey Rehabilitation Model. Dr. Esra founded the Contemporary Addiction Studies Association (ÇABAÇAD) in order to combat Turkey's growing addiction problem.