Blood Cancer Talks

In this episode, we discuss the management of acute toxicities of CAR T-cell therapy, including CRS, ICANS, and HLH with Dr. Michael Jain from Moffitt Cancer Center.

Here are some of the key articles we discussed:

1. “How I treat refractory CRS and ICANS after CAR T-cell therapy”. 
     https://pubmed.ncbi.nlm.nih.gov/36989488/
 
2. CAR-HEMATOTOX score: 
    https://pubmed.ncbi.nlm.nih.gov/34166502/
 
3. “How I treat cytopenias after CAR T-cell therapy”.
     https://pubmed.ncbi.nlm.nih.gov/36800563/
 
4. Immune Effector Cell-Associated HLH-Like Syndrome (ASTCT):
    https://pubmed.ncbi.nlm.nih.gov/36906275/
 
5. ASTCT consensus grading for CRS and ICANS:
    https://pubmed.ncbi.nlm.nih.gov/30592986/

6. Hematopoietic stem cell boost for persistent neutropenia after CAR T-cell therapy:
    https://pubmed.ncbi.nlm.nih.gov/35696759/
 
7. Modified EASIX score for predicting CRS and neurotoxicity:
    https://pubmed.ncbi.nlm.nih.gov/34432870/


What is Blood Cancer Talks?

This is a podcast on latest advances in the understanding and management of blood cancers. Here, we will bring a wide range of experts within hematologic malignancies to discuss various topics in depth.
Host: Raj Chakraborty, MD from Columbia University, New York, Ashwin Kishtagari, MD, from Vanderbilt University, Nashville, and Edward Cliff, MD, from Harvard University, Boston
Tweet your suggestions and feedback to @rajshekharucms @AshKishtagari @Eddie_Cliff @BloodCancerTalk