Thinking In Psychiatry

Access the mentioned paper here:

Trying to Unravel Why Alzheimer Disease Is More Common in Women
By Rita Rubin, MA

https://jamanetwork.com/journals/jama/article-abstract/2839498# 

Access mentioned courses here:

Women’s Mental Health Course:

https://psychscene.co/41RwJx2

Alzheimer’s Disease Course:

https://psychscene.co/4vNaeqH 

In this episode, Dr Sanil Rege examines why Alzheimer’s disease is more common in women and what this means for clinical assessment, prevention, and treatment.

The discussion reviews a 2025 JAMA medical news feature (https://jamanetwork.com/journals/jama/article-abstract/2839498#) on sex differences in Alzheimer’s disease and outlines a life-course model showing how sex-related vulnerability may shape disease onset, progression, and clinical expression.

This video provides clinicians with a sex-informed clinical framework for assessing Alzheimer’s risk in women through the lens of hormonal transitions, cognitive reserve, and later-life neurodegenerative expression.

Chapters:
00:21 Alzheimer’s Disease in Women
02:59 Beyond Longevity
03:40 Survival Differences After Dementia Diagnosis
04:34 Tau Pathology and Steeper Later Decline
06:00 Menopause and Hormonal Vulnerability
08:11 Modifiable Midlife Risk Factors in Women
13:18 A Sex-Informed Life-Course Formulation1

#Alzheimer's #Psychiatry #Dementia

What is Thinking In Psychiatry?

Thinking in Psychiatry is an Academy by Psych Scene podcast featuring short, high-signal audio episodes you can listen to on the go. Each week we break down emerging evidence, evolving clinical frameworks, and complex cases across the lifespan – from psychopharmacology and neurobiology to formulation, systems thinking, and metabolic and sleep psychiatry. Designed for busy clinicians, every episode is grounded in evidence, reviewed by faculty, and focused on one question: how can we practise better psychiatry, starting today?