Dietitian Nutritionist Leyla Muedin discusses a Stanford-led randomized controlled trial published in Nature Medicine in which a five-day, calorie-restricted fasting-mimicking diet improved symptoms and inflammatory markers in people with mild to moderate Crohn’s disease. In the three-month study of 97 patients, 65 followed monthly five-day cycles of 700–1100 calories/day with plant-based meals, while 32 continued usual diets; about two-thirds of the fasting-mimicking group reported symptom improvement, with fatigue and headaches but no serious side effects, and fecal calprotectin and other inflammatory molecules decreased. She notes bowel rest and the specific carbohydrate diet as additional approaches. The episode also explains how antibiotics can cause diarrhea by disrupting gut bacteria, lists higher-risk antibiotics, offers supportive steps (hydration, BRAT foods, avoiding irritants), recommends Saccharomyces boulardii taken away from antibiotics, and outlines warning signs requiring medical care, including possible C. difficile.
Creators and Guests
Leyla Muedin, MS, RD, CDN
Leyla has been a practicing nutritionist since 2003, when she started under the tutelage of the famed Dr. Robert Atkins at the Atkins Center for Complementary Medicine. Since 2005, she has worked alongside Dr. Hoffman at the Hoffman Center and then in private practice.
What is Intelligent Medicine | The Best of High Tech Medicine and Alternative Modalities?
Pioneering complementary medicine practitioner Dr. Ronald Hoffman takes a cutting-edge approach to health, wellness, and aging. He covers both conventional and alternative modalities, as well as nutrition, exercise, and supplements.