Weight and Metabolism

Energy balance sounds simple: calories in versus calories out. But it's actually a delicate conversation between the gut and the brain, orchestrated by the hypothalamus. Your brain and gut are in constant dialogue through the gut-brain axis, and this is the "neuro" piece of neurohormonal regulation.

For most of human history, diets were simple and unprocessed. Then came urbanization, industrial food systems, seed oils, high-fructose corn syrup, and ultra-processed foods engineered to taste irresistible. This shift fundamentally altered our energy balance physiology.
Here's the key: the chemical nature of calories matters. A small bag of chips has 150 calories. A medium apple has 150 calories. But chips cause a rapid blood sugar spike, insulin surge, sharp crash, and quick cravings. An apple causes a steady rise, slower decline, no crash, and no immediate craving. Same calories, completely different impact.


This is why re-regulating energy balance physiology is the cornerstone of successful weight management. It's not just about reducing calories. It's about choosing foods that work with your body's signals, stabilize blood sugar, and keep the gut-brain axis balanced. The success of any weight loss intervention depends on re-regulating this disrupted physiology.

🌐 Learn more at weightandmetabolism.com

What is Weight and Metabolism?

Dr. Deepti Sharma is a triple board-certified physician in Family Medicine, Obesity, and Lifestyle Medicine. She is also a certified menopause practitioner by The Menopause Society (previously NAMS) and a certified life coach. For over a decade, her clinical practice has focused on guiding individuals towards optimal health through evidence-based strategies.
She recognizes the unique challenges many individuals face in understanding their metabolism and managing their weight. This podcast is dedicated to addressing those specific nuances and providing clarity amidst widespread misinformation.
Each episode will delve into the science behind effective weight management and metabolic health exploring the critical roles of nutrition, physical activity, sleep, and mental well-being.

Please remember that while she is a doctor, she is not your doctor. This podcast is meant for educational and informational purposes only, not medical advice. Please consult your physician for your specific questions and needs.

Presented by Dr Deepti Sharma, MD
Learn more at www.weightandmetabolism.com