Trial Talk

At the start of October, lots of the Unit’s clinical trials methodology researchers travelled to Edinburgh, for the 7th International Clinical Trials Methodology Conference (ICTMC). ICTMC is the largest academic-led conference on clinical trials, bringing together trialists from across the globe to present their latest work in trials methodology. This year's conference featured a wide variety of workshops, talks and poster presentations from MRC Clinical Trials Unit researchers. I

n this latest episode of the Trial Talk podcast, four of the Unit’s early career researchers discuss the work they presented at ICTMC 2024. Gideon Darko Asamoah tells us how he will deliver a core outcome set for trials in severe malaria; Jingyi Xuan describes her project addressing intercurrent events in platform trials; Dongquan Bi discusses the effects of different cluster sizes in cluster trials; and finally, Kate Roberts explains how she aims to improve the wording around consent for accessing trial participants' healthcare records.

For questions or feedback on the series, message us at mrcctu.engage@ucl.ac.uk
For more information and to access the transcript: bit.ly/4f9grVi
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More resources:
• Developing a core outcome set for severe malaria trials poster: www.mrcctu.ucl.ac.uk/posters/identi…nd-caregivers/
• Specifying estimands and estimators in trials with complex designs poster: www.mrcctu.ucl.ac.uk/posters/specif…mplex-designs/
• Demystifying estimands in cluster-randomised trials paper in Statistical Methods in Medical Research: journals.sagepub.com/doi/10.1177/09622802241254197
• Estimands in cluster-randomised trials paper in International Journal of Epidemiology: academic.oup.com/ije/article/52/1/107/6644521
• Current practice around the use of estimands in cluster randomised trials, and the impact of informative cluster size on inference poster: www.mrcctu.ucl.ac.uk/posters/curren…on-inferences/
• ICTMC 2024 Poster 167 – A rap song (Lyrics by Dongquan Bi, beat by David Fitzgerald): youtu.be/s7qZ5TnOlWU?si=iXwfFfSAWwJ-fAmk
• CrossWord poster: www.mrcctu.ucl.ac.uk/posters/crossw…ing-materials/

 Date of episode recording: 2024-10-30T00:00:00Z
 Duration: 00:25:09
 Language of episode: English
 Presenter:Charlotte Hartley
 Guests: Gideon Darko Asamoah, Jingyi Xuan, Donguan Bi, Kate Roberts
 Producer: Charlotte Hartley
 

What is Trial Talk?

The Trial Talk Podcast explores how our work at the MRC Clinical Trials Unit at UCL is improving health in the UK and worldwide. In this new series, we will hear from world-leading experts about the studies we carry out. We will get inside trials on cancer, infections, and neurodegenerative diseases, explore how public and patient involvement is shaping our studies, and discover new ways to run smarter studies.