Dr. Sandra Kaufmann | The 7 Tenets of Aging: How to Slow Cellular Decline and Outlive Your Biology

Your cells start aging long before you feel it. By the time symptoms show up, the process has been running in the background for years.

In this episode of The Dr. K Show, Dr. Michael Karlfeldt sits down with Dr. Sandra Kaufmann, anesthesiologist, cell biologist, and author of The Kaufmann Protocol, to map out the seven core reasons cells break down with age and how to address each one systematically. The conversation covers mitochondrial health, glycation, protein misfolding, senescent cells, immune decline, and the repurposed pharmaceuticals most doctors never think to use for longevity. Dr. Kaufmann also walks through her own personal protocol, including what she takes daily, what she avoids, and why she built a completely different framework than what most longevity influencers are pushing.

Key Takeaways:

0:00 Introduction
4:10 Health span vs. lifespan: what longevity medicine actually means
6:45 Longevity pyramids: building a daily, weekly, and monthly protocol
9:18 The three tiers of medicine and why anticipatory care wins
9:44 The seven tenets of aging explained cell by cell
22:19 Glycation and the seven-step system to block AGE damage
34:41 Why Dr. Kaufmann skips rapamycin and what she takes instead

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Resources:

The Kaufmann Protocol: Aging Solutions – https://a.co/d/0iRdyJaA
Kaufmann Longevity — https://www.kaufmannlongevity.com

Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.

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MORE PODCASTS FROM DR. KARLFELDT: 
🎙 Integrative Cancer Solutions — Real patient stories and evidence-based integrative therapies for those navigating a cancer diagnosis. 
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What is The Dr. K Show?

Looking for a functional medicine podcast that actually explains how to fix your health?

The Dr. K Show with Dr. Michael Karlfeldt covers integrative medicine, functional medicine, biohacking, and longevity, with a focus on the root causes of chronic disease and practical strategies for optimizing energy, hormones, gut health, and cognitive performance.

With over 35 years of clinical experience, Dr. Karlfeldt interviews world-leading experts in metabolic health, detoxification, hormone balance, immune function, nervous system regulation, and chronic disease prevention. Each episode delivers science-backed, actionable insights by blending modern functional medicine with time-tested healing principles.

Whether you're struggling with fatigue, inflammation, hormonal imbalance, or simply want to perform at your best, this podcast gives you the tools to take control of your health and longevity.