Can Lyme disease begin before birth — and could it be driving neurodevelopmental conditions like autism, ADHD, and anxiety?
In this episode of Integrative Lyme Solutions, Dr. K is joined by Dr. Somer DelSignore, a leading pediatric integrative clinician, to explore the overlooked science of congenital Lyme and in utero transmission of vector-borne infections. Dr. DelSignore explains how infections such as Borrelia, Bartonella, and Babesia can cross the placenta, disrupt fetal brain development, and silently fuel inflammation that shows up later as behavioral, cognitive, and immune dysfunction.
You’ll learn why standard TORCH testing fails to catch these infections, what symptoms parents should watch for in infants and children, and how addressing inflammation, infections, and immune imbalance can dramatically improve outcomes. This episode offers critical insight for parents, practitioners, and anyone focused on true prevention and root-cause healing in pediatric Lyme disease.
Key Takeaways:
0:00 Introduction and Dr. Somer DelSignore’s clinical journey
3:10 From pediatric ICU to integrative Lyme care
6:20 Congenital Lyme: 40 years of overlooked science
9:00 Why TORCH testing misses vector-borne infections
12:45 Preconception testing and prevention strategies
15:30 Why treating Lyme before pregnancy matters
18:05 Infant symptoms parents should never ignore
21:10 Autism, neuroinflammation, and misdiagnosis
24:15 The RESET framework for pediatric healing
28:10 What real recovery can look like for children
Resources Mentioned:
IGeneX Laboratories – https://igenex.com
TLABDX (Babesia & Bartonella testing) – https://www.tlabdx.com/
Horowitz/MSIDS 38 point symptom checklist – https://projectlyme.org/msids-questionnaire/
IV Ozone Therapy – https://health.clevelandclinic.org/ozone-therapy
SOT (Supportive Oligonucleotide Therapy) – https://projectlyme.org/supportive-oligonucleotide-therapy-sot-for-lyme/
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
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WORK WITH DR. KARLFELDT:
The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies available. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor, contact us at:
📞 208-338-8902
📧 info@TheKarlfeldtCenter.com
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MORE PODCASTS FROM DR. KARLFELDT:
🎙 The Dr. K Show — Integrative medicine, functional medicine, biohacking, and longevity for optimizing health and performance.
🎙 Integrative Cancer Solutions — Evidence-based integrative therapies and real patient stories for those navigating a cancer diagnosis.
Explore all shows on https://www.youtube.com/@KarlfeldtCenter
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Struggling with chronic Lyme disease and not getting answers from conventional medicine?
Integrative Lyme Solutions with Dr. Michael Karlfeldt explores evidence-based, integrative approaches to chronic Lyme disease, tick-borne illness, and co-infections — including Bartonella, Babesia, and Ehrlichia — through expert interviews and real patient recovery stories.
Lyme disease is known as the "great imitator" because its symptoms overlap with dozens of complex conditions, including Chronic Fatigue Syndrome (ME/CFS), fibromyalgia, autoimmune disorders, Multiple Sclerosis, and Parkinson's disease. Many patients spend years misdiagnosed or dismissed after false-negative Western blot results. This podcast cuts through the confusion with practical insights on functional medicine, herbal antimicrobials, detoxification, immune support, nervous system healing, and other integrative therapies that support long-term recovery.
With over 35 years of clinical experience, Dr. Karlfeldt brings the knowledge of a Lyme literate naturopathic doctor to every episode — helping patients and caregivers reduce their research time, ask better questions, and find a path forward.