Registered dietitian Leyla Muedin discusses a Frontiers in Microbiology paper suggesting certain probiotics may help sequester heavy metals. The study, sponsored by the Italian company Probiotical and conducted with University of Ghent and University of Piedmont Orientale, researchers used in vitro testing and the SHIME gut simulator to assess Lactiplantibacillus plantarum, Lactobacillus crispatus, and Lactobacillus acidophilus against cadmium, lead, chromium, and mercury. L. plantarum and L. crispatus reduced metal bioavailability primarily in the simulated colonic phase, while L. acidophilus showed minimal detoxification; mercury was least reduced (~10%). An ex vivo mouse-intestine system found probiotic pre-incubation of metals preserved epithelial integrity and reduced inflammatory responses. Leyla notes limitations: corporate funding, only three strains tested, and no in vivo or human trials, though the findings support further animal and clinical research.
Creators and Guests
Leyla Muedin, MS, RD, CDN
Leyla has been a practicing nutritionist since 2003, when she started under the tutelage of the famed Dr. Robert Atkins at the Atkins Center for Complementary Medicine. Since 2005, she has worked alongside Dr. Hoffman at the Hoffman Center and then in private practice.
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Pioneering complementary medicine practitioner Dr. Ronald Hoffman takes a cutting-edge approach to health, wellness, and aging. He covers both conventional and alternative modalities, as well as nutrition, exercise, and supplements.