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Dr Emma Hancox: Hi and a warm welcome
to the new Synaptic Tails podcast.

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I'm your host, Emma Hancox,
a Technical Vet Advisor from

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TVM UK, a Dômes Pharma Brand.

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And I'm here in collaboration with Dr.

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Mark Lowrie of Movement Referrals.

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I'm sure you’re all familiar with
Mark's name, but just by way of

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introduction, Mark qualified from the
University of Cambridge before working

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in first opinion small animal practice.

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Following an internship at the Royal
Veterinary College, he moved to the

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University of Glasgow to complete a
residency in veterinary neurology.

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Mark worked for several years at a
leading multidisciplinary centre near

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London, then as Clinical Director
for another multidisciplinary

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referral centre in the East Midlands.

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Mark has a master's degree on steroid
responsive meningitis arteritis

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in dogs, and has a particular
interest in management of movement

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disorders, inflammatory brain and
spinal disease and feline neurology.

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He is Veterinary Consultant to the
International Society of Feline

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Medicine, the ISFM, and was awarded,
finally, the prestigious national prize

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of Petplan Vet of the Year in 2022.

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That is quite some introduction Mark.

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Welcome, how are you?

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Dr Mark Lowrie: Sorry to
make you read all that out.

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Thank you very much.

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No, all's good today.

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And it's nice to be in this room

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Dr Emma Hancox: Good.

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Good.

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For those that don't know, Mark has
recently opened a new independent referral

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centre in the Northwest with four of
his orthopaedic veterinary specialists,

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colleagues, maybe also friends, I think.

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Tell us a little bit
about Movement Referrals.

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How's it going?

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Dr Mark Lowrie: Oh, it's exciting.

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I could talk about this all day.

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So

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Dr Emma Hancox: Please don't, I'm joking.

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Dr Mark Lowrie: It was set
up by five of us in total.

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The other four are well-known veterinary
specialists in orthopaedics, we want

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to provide sort of high quality but
efficient specialist referral services.

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We obviously just concentrate
on orthopaedics and neurology,

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and they're two of the most
common reasons for referrals.

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We're able to offer common
referral procedures such as TPLO,

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patellar luxation, don't ask me
about them, and spinal surgery

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at really reasonable prices.

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Given the dramatic consolidation
of recent years in the veterinary

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world, and the importance of GP vet
recommendations in the referral process,

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I suppose it's fair to say there's
been a reduction in competition and

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significant price inflation, so we
really hope to provide more choice at

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better value and aim to objectively
demonstrate our value through

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measuring and publishing our outcomes.

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Dr Emma Hancox: That's brilliant.

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Dr Mark Lowrie: I think it's important
for owners to know what they can expect

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when they take their dog for surgery.

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What is the likely outcome going to be?

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And if we can publish what we've
done in the past, they've got

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quite clear guidelines on that.

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We've had a great few months.

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We've not been open long, got big plans
ahead, and we abide by the statement

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of getting it right first time.

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So that's one of the reasons something
like canine epilepsy that we talk

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about today is so important as I
feel it's that first meeting that

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can dictate the direction of an
owner's decision and the direction

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that things might take in the future.

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Dr Emma Hancox: Absolutely.

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And I think having both that neurology
and that orthopaedic kind of influence

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is really useful because, it's
so easy in first opinion practice

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to sometimes misdiagnose these.

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So I guess it's great to see,
or have, that influence of your

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colleagues as well and have both of
those kind of inputs and you can all

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look at cases together sometimes.

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Dr Mark Lowrie: The two
marry together brilliantly.

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So the number of times we'll see something
that we feel is orthopaedic and it

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becomes neurological and vice versa.

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So it's great.

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And as you said earlier on, I'm
working with my mates, that's always

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a good thing, always good fun.

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Dr Emma Hancox: You always have
to have fun when you’re at work.

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That's brilliant though, Mark,
we're so lucky to have you here.

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Our new podcast will focus on how
to manage neurology cases in first

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opinion practice, hopefully offering
you some tips and tricks that

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we've both learned along the way.

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Over the first few episodes, we're
going to introduce you to TVMs new

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S.M.A.R.T Approach To Epilepsy, and how
to apply this to some real life cases.

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Some of you may have seen this
already in lunch and learns, so if

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you haven't already, you can always
book those via our website as well.

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The aim of the S.M.A.R.T Approach
To Epilepsy is to help you guide

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conversation in first opinion practice.

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So it's not really anything that
you as vets don't know in practice,

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but it's just there as a reminder.

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S.M.A.R.T is, of course, an acronym
because we all know how much marketers

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love an acronym, and stands for speak,
measure, advise, realistic and tailor.

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So that's going to be our focus
for the next few episodes.

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This has been largely based on some
recent work that was published at the

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beginning of the year, in the vet record.

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So from authors, Amy Pergande, Zoe
Belshaw, Holger Volk and Rowena Packer,

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which was the first to look at how owner
perspectives of their vet and their

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vet owner bond impacts upon decision
making and ultimately how this impacts

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upon clinical outcomes for epilepsy.

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And this is why speak and
communication is at the beginning

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of that S.M.A.R.T approach because
it's so important yet, honestly, is

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quite often overlooked in practice.

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I think I can hold my hands
up and say, I always looked

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at the numbers, to be honest.

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This is something that we had discussed
the first time we met, wasn't it Mark?

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Actually, that kind of
communication and time in practice

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is one of the biggest hurdles.

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Dr Mark Lowrie: Time.

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Yeah, time.

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There just isn't enough time.

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Dr Emma Hancox: There
isn't, really isn't, no.

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Dr Mark Lowrie: And these cases don't
come in when you've got lots of time.

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They're inevitably going to come in when
you've got 10 other patients to see.

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The waiting room is full to bursting,
dogs are attacking each other.

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You can imagine the scene.

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But the owner, when they first come
in, they've obviously in the very

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recent past, witnessed their dog have
a fit, which is such a scary thing.

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Dr Emma Hancox: Absolutely.

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Dr Mark Lowrie: To see.

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So you’re suddenly in this position
counselling as well as preparing them

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what's ahead, and you've probably got
5, 10, maybe 15 minutes if you’re lucky.

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Dr Emma Hancox: If you’re
lucky, I was gonna say.

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Dr Mark Lowrie: So I think if you’re
able to have a really long period

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of time to sit down with these
owners, it makes a huge difference.

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And I'm sure as you’re all
listening to this, you probably

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think, I don't have that.

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I don't have that time.

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So signposting is really helpful
here to get an owner to know where to

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look to get the information they need
because you’re not going be able to

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provide it in the time that you've got.

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I think there's a role for all
members of the practice here.

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So, the owner's phoned up, they've
said my dog's had a fit, and they

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want to book in to see the vet.

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But the receptionist there, the
person answering the phone can

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help a little bit and say, actually
we've got some information on this.

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And you can direct them to
that information, whether it's

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something on your own website.

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Some leaflets indeed, TVM could
provide information around

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this to support these clients.

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I think that really helps just to
settle them down while they're waiting

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for that appointment or even while
they're waiting in the waiting room.

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Dr Emma Hancox: Yeah.

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Dr Mark Lowrie: It can help enormously.

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The other thing that's omitted is owners
aren't prepared with what's ahead.

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They're coming in having seen
their dog have a fit, and they

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never want to see that ever again.

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Dr Emma Hancox: Yeah.

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Dr Mark Lowrie: And that's not realistic.

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We can't do that.

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If we could, that would be amazing.

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Owners need to be ready that there's gonna
be a lot more fits ahead, most likely.

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And the most important thing that's
never ever said, if we are dealing

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with epilepsy, which we'll assume
here, this is a dog that's had its

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first fit and it's got epilepsy,
it's a progressive condition,

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it's going to get worse and worse.

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Now, that's miserable.

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Dr Emma Hancox: Yeah.

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And I think as vets, we don't
wanna say that, we don't want

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to be the bearers of bad news in
that stressful situation, do we?

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But it was certainly something that was
picked out actually of that paper that I

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mentioned, that actually being realistic
with those owners and having that frank

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conversation upfront was one of the, even
if they don't wanna hear it, is one of

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the positive outcomes from that paper.

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So it's, as I said, it's stuff that
you do know, but it's just putting that

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into perspective a little bit as well.

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Dr Mark Lowrie: And if you are that
honest vet that gives that information,

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that's what's gonna help that bond
between you and the client because

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they'll, you’re not telling the
owners something they want to hear.

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you’re telling them something they
need to hear and they may not take

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it well, they may take it great, but
then they'll go away, have a think

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about it and say, you know what?

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My vet was really honest from the get go.

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And that's gonna put you absolutely
on the right grounding for the future.

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So they know that, you’re not a miracle
worker, but you’re there for them and

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you can help advise them through it.

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So that is so important
right from the beginning.

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Dr Emma Hancox: Yeah.

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You mentioned that there was a role
for other members of the veterinary

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staff, you picked up the front of house
staff there, and I think it is really

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useful for them to at least have that
kind of triage type advice as well

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when they first get that phone call.

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It just, again, instils that confidence.

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But again, something in this paper is
suggesting that owners like to talk to

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the nurses as well and maybe confide
a lot in them, some things that they

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might not confide in their vets.

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So actually, and we know that nurses are
brilliant at doing their nurse clinics.

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They will, often do things like OA clinics
and things like that for us then it's

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unfortunate that I don't see sometimes
a lot of epilepsy type clinics where I

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think actually they could get involved.

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What do you think about that?

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Dr Mark Lowrie: Oh, I think that's vital.

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So I’ve mentioned the
receptionist, but yeah, the nurse.

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What can the nurse do?

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So much!

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So you've got that owner, they've turned
up in the waiting room, their dog's had a

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fit potentially, it's still having a fit.

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We've got to remember that.

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So triage, absolutely.

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I think if there's a veterinary
nurse available, who can bring

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the owners and the dog to one
side and have a chat with them.

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If the dog's actively fitting, well
clearly the role of the nurse is to

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bring the dog through and make sure it
receives that veterinary attention with

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the vet immediately, so that's easy.

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We know that.

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I think everyone would
be familiar with that.

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But in the scenario where the
dog stopped fitting, the owner's

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probably still panicking.

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And I think for the nurse to take
them to one side, reassure them, but

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something that isn't done much, and I
think this is where the nurse can help,

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is just to get information from the
owners as to what it is they've seen.

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Dr Emma Hancox: Yeah.

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Dr Mark Lowrie: Now a vet can do
this, but they haven't got much time,

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so you don't want to spend a lot of
the veterinary consultation talking

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about how the fit looked, because
you want to cut to the chase and get

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to the nitty gritty of what's ahead.

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So for a veterinary nurse, I think it's
a really good opportunity for them to

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ask key questions about what the fit
looked like, to check it truly was a fit.

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The smartphone's been amazing
because the smartphone allows you to

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witness these episodes in real time.

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So in the past, an owner would come
in, they say 'My dog's had a fit,

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a seizure', whatever it might be.

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And an assumptions made that's
exactly what the dog's having.

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But if you get video footage
of what's happening, because

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we never see them in practice.

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In fact, I joke that I'm probably the
best anti-epileptic device there is

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'cause I never see a fit in practice.

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Dr Emma Hancox: So we all need you
just at home with us basically.

227
00:11:02,214 --> 00:11:02,394
Dr Mark Lowrie: Just me.

228
00:11:02,394 --> 00:11:02,454
Yeah.

229
00:11:02,454 --> 00:11:04,199
I’ll come and I’ll take
myself home with the owners.

230
00:11:04,214 --> 00:11:05,644
I’ve not worked out my charge or
hourly rate yet but we can do that,

231
00:11:05,644 --> 00:11:06,354
I don't know, you can brand me.

232
00:11:06,494 --> 00:11:06,854
Dr Emma Hancox: That's it.

233
00:11:06,854 --> 00:11:11,374
We've got a new treatment
from this podcast!

234
00:11:12,264 --> 00:11:17,044
Dr Mark Lowrie: But if you can get the
owners to, to film the episode, then

235
00:11:17,044 --> 00:11:20,104
that helps because the vet, the nurse
can look at that in their own time.

236
00:11:20,494 --> 00:11:24,474
But the nurse can ask questions such
as, well refer to autonomic signs

237
00:11:24,499 --> 00:11:26,959
to say, has the dog been salivating?

238
00:11:27,709 --> 00:11:29,899
Has it urinated during an episode?

239
00:11:30,199 --> 00:11:32,779
If you are getting salivation
during an episode, that for me

240
00:11:32,779 --> 00:11:34,309
is a sure fire hit that it's a

241
00:11:34,654 --> 00:11:34,879
Dr Emma Hancox: Yeah.

242
00:11:34,879 --> 00:11:34,939
Yeah

243
00:11:36,589 --> 00:11:41,019
Dr Mark Lowrie: If you've got a dog that's
moving all four legs, very uncontrollably,

244
00:11:41,919 --> 00:11:45,989
but remains alert, that's ringing an
alarm bell, this might not be a fit.

245
00:11:47,309 --> 00:11:47,489
A

246
00:11:47,489 --> 00:11:50,039
great example of this would
be, again, going back to that

247
00:11:50,039 --> 00:11:52,209
busy consultation clinic.

248
00:11:52,689 --> 00:11:56,049
Your vet's there seeing lots of
cases in, lots of vaccinations, and

249
00:11:56,054 --> 00:11:57,579
the odd vomiting dog here and there.

250
00:11:58,509 --> 00:12:02,414
They're really busy running late, and the
phone call comes through that an owner has

251
00:12:02,419 --> 00:12:06,604
a dog that's fitting and the conversation
would normally go, something along the

252
00:12:06,604 --> 00:12:10,354
lines of, my dog's been fitting for
the last 20 minutes and hasn't stopped.

253
00:12:11,584 --> 00:12:13,724
So naturally the receptionist
has taken that call and gone, you

254
00:12:13,724 --> 00:12:15,314
need to come down straight away.

255
00:12:16,184 --> 00:12:20,294
So they pile the dog in the car, they
come down, the clinic's full to bursting.

256
00:12:20,894 --> 00:12:24,674
And then this Labrador that's been fitting
for 20, maybe 30, 40 minutes by the

257
00:12:24,679 --> 00:12:29,864
time it arrives, comes running into the
waiting room, bouncing around, crazily

258
00:12:29,864 --> 00:12:33,524
looking probably the healthiest dog in
the waiting room there and then, and

259
00:12:33,524 --> 00:12:34,784
everyone thinks what's going on here?

260
00:12:34,834 --> 00:12:35,934
This owner's been lying.

261
00:12:36,424 --> 00:12:38,029
And of course the owner hasn't been lying.

262
00:12:38,149 --> 00:12:42,049
This dog has clearly had a
prolonged episode that was very

263
00:12:42,049 --> 00:12:46,939
abnormal, but they've gone straight
back to normal very quickly.

264
00:12:47,749 --> 00:12:50,989
And when you get a dog that bounces
straight back to normal very quickly and

265
00:12:50,989 --> 00:12:55,129
back to normal consciousness and behaving
normally, if they truly were fitting

266
00:12:55,134 --> 00:12:57,409
for 20 or 30 minutes, that's not a fit.

267
00:12:57,454 --> 00:12:57,744
Dr Emma Hancox: Yeah.

268
00:12:58,369 --> 00:12:59,839
Dr Mark Lowrie: So
something else was going on.

269
00:13:00,199 --> 00:13:05,164
So your veterinary nurse can take a look
at that dog and say, this is a really

270
00:13:05,164 --> 00:13:09,664
normal looking dog given it's been fitting
for so long and that then tells us maybe

271
00:13:09,664 --> 00:13:13,534
this isn't epilepsy and to consider other
possibilities for what might be going on.

272
00:13:13,924 --> 00:13:18,934
Whereas, of course, if the dog comes
in, it looks drunk, confused, blind, it

273
00:13:18,939 --> 00:13:21,094
doesn't interact with the other patients.

274
00:13:21,394 --> 00:13:21,454
Dr Emma Hancox: Yeah.

275
00:13:21,454 --> 00:13:24,214
Dr Mark Lowrie: In the waiting
room, yes, a fit is definitely

276
00:13:24,214 --> 00:13:24,874
what we're dealing with.

277
00:13:25,399 --> 00:13:27,409
Dr Emma Hancox: And that's,
that can be both things really.

278
00:13:27,409 --> 00:13:31,219
So yes, it's getting vital information
that they can pass back to the rest of

279
00:13:31,219 --> 00:13:33,229
the team, the vets that are in charge.

280
00:13:33,559 --> 00:13:37,879
But also if that dog does come bounding
in and is quite happy, they can almost

281
00:13:37,969 --> 00:13:42,589
immediately reassure the owner that
actually your dog is looking well right

282
00:13:42,589 --> 00:13:45,303
now so not to worry so much

283
00:13:45,353 --> 00:13:48,083
Dr Mark Lowrie: And that's great because
then hopefully it calms the owners.

284
00:13:48,353 --> 00:13:52,523
So they're ready to get the information
they need to know what's happening next.

285
00:13:53,063 --> 00:13:55,763
It's so difficult delivering
information to someone who's panicking.

286
00:13:56,543 --> 00:14:00,143
I always say if you’re in an emergency
and you’re in a room with a big red

287
00:14:00,143 --> 00:14:03,713
button on the wall that everybody can
see, and you’re told to press the big

288
00:14:03,713 --> 00:14:05,453
red button in a hurry, you never see it.

289
00:14:05,693 --> 00:14:06,683
You look everywhere around.

290
00:14:06,683 --> 00:14:07,973
You can't see the big red button.

291
00:14:08,243 --> 00:14:10,433
You can only see the red button
when you’re relaxed and calm.

292
00:14:10,493 --> 00:14:14,573
So yeah, you want to calm an owner and
then deliver the information carefully.

293
00:14:14,948 --> 00:14:15,428
Dr Emma Hancox: Absolutely.

294
00:14:16,343 --> 00:14:22,643
Just to summarize in an emergency
situation, it's obviously, communication

295
00:14:22,643 --> 00:14:26,453
with the owner is going to be important,
one, in terms of ascertaining what's

296
00:14:26,453 --> 00:14:32,153
happened and trying to get that accurate
diagnosis, but also, to calm them down

297
00:14:32,603 --> 00:14:36,783
as well, and to give them all of that
kind of advice and time for that advice.

298
00:14:37,083 --> 00:14:41,763
How does that differ, do you
think, when you see them as

299
00:14:41,763 --> 00:14:43,833
like a chronic, ongoing case?

300
00:14:44,053 --> 00:14:47,713
So how would your kind
of conversation change?

301
00:14:47,893 --> 00:14:50,893
I guess it's now more about
things like quality of life

302
00:14:51,223 --> 00:14:52,903
of that pet and that owner.

303
00:14:53,193 --> 00:14:55,443
Obviously we're still going to
need to talk about the seizures

304
00:14:55,443 --> 00:14:59,823
and their frequency, but perhaps
more about quality of life now.

305
00:14:59,898 --> 00:15:02,448
Dr Mark Lowrie: It is quality of life,
and I think the owners, I’ve said

306
00:15:02,453 --> 00:15:05,208
already, they need to know what's
coming ahead, what's in the future.

307
00:15:05,208 --> 00:15:08,748
So I don't mean crystal ball gazing,
not that sort of thing, but for the

308
00:15:08,748 --> 00:15:10,188
owners to know more fits will happen.

309
00:15:11,018 --> 00:15:12,378
And what's that mean for a dog?

310
00:15:12,978 --> 00:15:16,518
Now, I think it really helps here to
relate it to the human condition of

311
00:15:16,518 --> 00:15:21,228
epilepsy because also commonly you'll
find that owner has some form of

312
00:15:21,228 --> 00:15:24,708
experience of epilepsy in people, whether
it be a relative, a friend, maybe in

313
00:15:24,708 --> 00:15:26,718
the job they do, they come across it.

314
00:15:27,678 --> 00:15:30,498
And if they know someone with epilepsy,
I'd encourage them to speak to them.

315
00:15:30,558 --> 00:15:33,258
Because if you speak to a person
with epilepsy, they'll tell you

316
00:15:33,258 --> 00:15:35,148
that it's not a painful condition.

317
00:15:35,268 --> 00:15:36,618
There's no pain or discomfort.

318
00:15:36,978 --> 00:15:38,388
Owners always worry about pain.

319
00:15:38,478 --> 00:15:40,968
It doesn't matter whether we're talking
about epilepsy or anything else.

320
00:15:41,298 --> 00:15:43,278
Pain is always their number one concern.

321
00:15:44,268 --> 00:15:45,408
So this isn't painful.

322
00:15:46,098 --> 00:15:49,668
And when you speak to a person with
epilepsy, when they have a fit, what

323
00:15:49,668 --> 00:15:54,828
they'll say is they're completely unaware
of what's happening in the moment.

324
00:15:55,638 --> 00:15:59,698
And so, if they're in a room full of
people and they have a fit, they're fine.

325
00:16:00,178 --> 00:16:01,738
They've got no problem at all.

326
00:16:02,533 --> 00:16:06,163
When they come round from the fit, it's
everyone else in the room that's panicking

327
00:16:06,523 --> 00:16:11,683
and doing things and maybe doing silly
things like putting your hand in their

328
00:16:11,688 --> 00:16:13,603
mouth to try and establish an airway.

329
00:16:13,633 --> 00:16:14,623
Why would you do that?

330
00:16:14,683 --> 00:16:17,923
But in the heat of the moment, people
do these silly things and get bitten.

331
00:16:18,103 --> 00:16:19,813
So of course we don't do that for dogs.

332
00:16:19,813 --> 00:16:21,673
We keep our hands well
away from their mouths.

333
00:16:22,513 --> 00:16:26,563
But if you just apply logic to it,
it's good to inform an owner that when

334
00:16:26,563 --> 00:16:28,993
their dog has a fit, try not to panic.

335
00:16:29,767 --> 00:16:32,347
Ensure they're in an area where they're
not gonna hurt themselves because

336
00:16:32,347 --> 00:16:36,757
they're gonna be thrashing around,
usually at home, it is important,

337
00:16:36,757 --> 00:16:40,427
I haven't said, but epilepsy always
happens at home when a dog's relaxed,

338
00:16:40,427 --> 00:16:42,377
it doesn't tend to happen out on walks.

339
00:16:42,677 --> 00:16:47,212
We don't go out for a walk in the Peak
District and see dogs fitting left,

340
00:16:47,217 --> 00:16:50,242
right and centre, yet we know there's
a lot of epileptic dogs out there.

341
00:16:50,292 --> 00:16:51,132
Dr Emma Hancox: it's very true, actually.

342
00:16:51,132 --> 00:16:51,962
I hadn't thought about that.

343
00:16:51,962 --> 00:16:53,982
Dr Mark Lowrie: No, if you’re at the
playground with your kids pushing 'em

344
00:16:53,982 --> 00:16:56,652
on a swing, you don't tend to see, oh,
there's a dog over there having a fit.

345
00:16:57,267 --> 00:16:59,637
But, so it's always when they're relaxed.

346
00:16:59,847 --> 00:17:04,057
So when they're resting at home,
early in the morning, late at night.

347
00:17:04,107 --> 00:17:07,077
Vets covering emergency clinics
will be very familiar with the

348
00:17:07,082 --> 00:17:09,597
phone calls, whereas vets during
the day won't get them so much.

349
00:17:09,612 --> 00:17:10,092
Dr Emma Hancox: It's true.

350
00:17:10,172 --> 00:17:10,462
Yeah.

351
00:17:11,107 --> 00:17:13,147
Dr Mark Lowrie: It does happen when
these dogs are relaxed and not to worry

352
00:17:13,147 --> 00:17:14,347
about treating their dogs normally.

353
00:17:14,377 --> 00:17:16,757
They can go out on a walk, they
can go about their daily routine.

354
00:17:17,447 --> 00:17:20,152
But when they are fitting in the house,
move the furniture out the way, make

355
00:17:20,152 --> 00:17:23,062
sure they don't hurt themselves and
maybe, if it's a bright room, dim the

356
00:17:23,062 --> 00:17:26,182
lights, and just be ready to be there
for your dog when they come round.

357
00:17:27,532 --> 00:17:32,272
And a concern for a lot of owners is
the behaviour following the seizure.

358
00:17:32,782 --> 00:17:36,082
And I’ve come across a few
situations now quite frequently,

359
00:17:36,082 --> 00:17:38,452
where the seizure is a worry.

360
00:17:38,482 --> 00:17:40,942
Of course it is for the owners,
but it's the behaviour following

361
00:17:40,962 --> 00:17:42,492
the fit that can be a concern.

362
00:17:44,142 --> 00:17:49,662
The behaviour, typically we will see
ataxia, so a drunken gait, blindness,

363
00:17:49,662 --> 00:17:53,532
potentially all fairly transient,
hopefully lasting, no more than 5, 10

364
00:17:53,532 --> 00:17:57,732
minutes, but it will be longer if the
seizure's been going on for longer.

365
00:17:58,362 --> 00:17:59,502
But the big one is aggression.

366
00:18:00,492 --> 00:18:04,182
Dogs come around really disorientated
and they will show aggression.

367
00:18:04,182 --> 00:18:05,922
Now that's probably fear aggression.

368
00:18:05,982 --> 00:18:07,392
It could be the brain doing things.

369
00:18:07,572 --> 00:18:09,702
It's hard to explain
exactly why that happens.

370
00:18:09,802 --> 00:18:13,222
But it occurs, and so owners can find
themselves in quite a threatening

371
00:18:13,222 --> 00:18:14,962
situation with their beloved pet.

372
00:18:15,832 --> 00:18:18,712
And I think all you can say
in that situation is just try

373
00:18:18,712 --> 00:18:19,642
and keep away from your dog.

374
00:18:19,642 --> 00:18:22,992
Allow it to be in an enclosed room,
just to come round and hopefully

375
00:18:23,082 --> 00:18:24,702
after 5, 10 minutes they'll be better.

376
00:18:25,512 --> 00:18:28,272
But it's when children and other
vulnerable family members are

377
00:18:28,272 --> 00:18:29,802
present, that is a big concern.

378
00:18:30,552 --> 00:18:32,502
And we can't treat postictal signs.

379
00:18:32,622 --> 00:18:34,842
We can only manage the seizure activity.

380
00:18:35,022 --> 00:18:38,802
So the fewer seizures you have, the
less this aggression will be seen.

381
00:18:39,387 --> 00:18:41,957
So it all comes back down
to the medication and what

382
00:18:41,957 --> 00:18:43,197
we can do to help with that.

383
00:18:43,287 --> 00:18:43,647
Dr Emma Hancox: Yeah.

384
00:18:43,917 --> 00:18:44,727
Oh, that makes sense.

385
00:18:45,567 --> 00:18:48,717
And picking up on what you
said about them being outside

386
00:18:48,877 --> 00:18:50,527
can we still enjoy our walks?

387
00:18:50,527 --> 00:18:52,027
Can we still go out for the day?

388
00:18:52,027 --> 00:18:53,617
Can we still do all of these things?

389
00:18:53,617 --> 00:18:58,407
And I think we don't want to see epilepsy
as a life sentence for these dogs.

390
00:18:59,227 --> 00:19:02,197
We're all here for them to have a good
quality of life at the end of the day.

391
00:19:02,557 --> 00:19:05,497
Dr Mark Lowrie: Absolutely, and I think
there's two things I'd add there, but

392
00:19:05,497 --> 00:19:09,757
the first one would be I’ve said that
I'm a good anti-epileptic medication.

393
00:19:10,027 --> 00:19:14,557
My second top tip here is taking dogs for
a walk is a great anti-epileptic strategy.

394
00:19:15,457 --> 00:19:17,212
It's not endorsed by
anybody other than myself.

395
00:19:17,212 --> 00:19:22,132
It is only my opinion, but I think
taking a dog out on a walk, if they

396
00:19:22,132 --> 00:19:25,072
are about to have a fit, as long as
you've not caught it too late, I think

397
00:19:25,072 --> 00:19:26,692
it can offset that seizure for a bit.

398
00:19:26,902 --> 00:19:29,512
Importantly, I think it offsets
it rather than prevents it.

399
00:19:30,112 --> 00:19:33,262
But going out on a walk
is a great activity to do.

400
00:19:33,382 --> 00:19:34,642
I would be very happy to do it.

401
00:19:35,182 --> 00:19:39,502
And then the second point would be
dogs with epilepsy, they are really

402
00:19:39,562 --> 00:19:43,592
normal dogs otherwise, so they,
they can go about a normal life.

403
00:19:43,622 --> 00:19:46,382
I can think of dogs I’ve treated
where they're sniffer dogs, they

404
00:19:46,382 --> 00:19:47,672
sniff out drugs and do all that

405
00:19:47,672 --> 00:19:48,302
brilliantly.

406
00:19:49,022 --> 00:19:51,482
but their life's interspersed
with the odd fit here and there.

407
00:19:51,572 --> 00:19:55,082
They're on medication, they're managed,
they have a great quality of life and

408
00:19:55,082 --> 00:19:56,282
they're doing a brilliant service.

409
00:19:56,432 --> 00:19:56,822
Dr Emma Hancox: Yeah.

410
00:19:57,152 --> 00:19:59,852
Dr Mark Lowrie: So that should be
enough for these owners that are

411
00:19:59,852 --> 00:20:04,772
faced with a diagnosis of idiopathic
epilepsy, that actually their dog

412
00:20:04,772 --> 00:20:06,512
should have a good quality of life.

413
00:20:07,832 --> 00:20:11,102
Dr Emma Hancox: It almost doesn't
make sense to me though, because when

414
00:20:11,102 --> 00:20:16,172
I think about seizure activity, it's
almost described as too much activity.

415
00:20:16,172 --> 00:20:21,572
So why then stimulating them and
going out for a walk and getting

416
00:20:21,572 --> 00:20:24,872
them to hear things and do things
and how does that stave it off?

417
00:20:24,872 --> 00:20:26,282
That's just fascinating to me.

418
00:20:26,282 --> 00:20:27,152
I guess we don't know.

419
00:20:27,332 --> 00:20:29,642
Dr Mark Lowrie: And we don't
know and I think, no, I think

420
00:20:29,642 --> 00:20:32,162
it's a really fair question and
I think it's important to say.

421
00:20:32,577 --> 00:20:35,607
it's all right if so, if you litreally
see your dog about to go into a

422
00:20:35,607 --> 00:20:37,387
fit, this strategy isn't gonna work.

423
00:20:37,497 --> 00:20:38,487
you’re already too late.

424
00:20:38,487 --> 00:20:41,577
So I think if you are getting
the aura of signs that a fit's

425
00:20:41,577 --> 00:20:42,747
about to come on, it's too late.

426
00:20:42,747 --> 00:20:46,917
But I think just distracting a dog
with other activities, it just, it's

427
00:20:46,922 --> 00:20:49,707
a way of allowing the body to function
normally and it stops it happening.

428
00:20:50,067 --> 00:20:52,647
But yeah, I have to be honest
to say we don't know  why it

429
00:20:52,667 --> 00:20:55,217
works and it's not proven either.

430
00:20:55,257 --> 00:20:57,387
This is my view but it seems to work well.

431
00:20:57,387 --> 00:20:59,627
Dr Emma Hancox: So your two treatments
that you’re advocate in here is

432
00:20:59,632 --> 00:21:01,007
you and going out for a walk.

433
00:21:01,112 --> 00:21:03,582
Dr Mark Lowrie: It's great, so much,
you'll be out of business as a company

434
00:21:03,832 --> 00:21:04,937
Dr Emma Hancox: We're going be, aren't we?

435
00:21:05,297 --> 00:21:06,407
Why did we invite you again?

436
00:21:07,887 --> 00:21:08,427
Oh dear.

437
00:21:08,837 --> 00:21:13,902
on the flip side of that though, is
it true that stressful environments,

438
00:21:13,902 --> 00:21:17,952
so vet visits and things like that,
increase the risk of seizures?

439
00:21:17,952 --> 00:21:22,632
I think that's a concern of peoples,
whether that be vets or owners.

440
00:21:22,632 --> 00:21:24,042
I just use the word people there.

441
00:21:24,372 --> 00:21:25,032
Is that true?

442
00:21:25,032 --> 00:21:25,782
Do you see that?

443
00:21:26,742 --> 00:21:26,922
Dr Mark Lowrie: Yeah,

444
00:21:27,072 --> 00:21:32,622
it's quite rare, and seizures happen more
commonly in relaxed environments, but

445
00:21:32,622 --> 00:21:37,002
there's absolutely no question we come
across the odd patient that it clearly,

446
00:21:37,432 --> 00:21:39,592
the fit has a clear, stressful trigger.

447
00:21:39,952 --> 00:21:45,512
So going into a vet we'll have dogs
that maybe require some kind of sedative

448
00:21:45,512 --> 00:21:49,202
or anti-epileptic medication before
arriving to try and offset that fit.

449
00:21:49,787 --> 00:21:52,517
It is rare, and it's not a common
finding, but it does occur.

450
00:21:52,887 --> 00:21:55,427
And other fits, they're
called reflex seizures.

451
00:21:56,297 --> 00:21:59,057
They're seizures that happen
in response to a stimulus.

452
00:21:59,057 --> 00:22:03,167
So there was a dog I saw once that it
was going outside that actually triggered

453
00:22:03,167 --> 00:22:05,227
a seizure, it was remarkably reliable.

454
00:22:05,247 --> 00:22:09,507
So that dog, I wouldn't have taken
for a walk to stop the fit, but they'd

455
00:22:09,512 --> 00:22:13,197
go out and the light outside would
just trigger a seizure, but take

456
00:22:13,197 --> 00:22:14,667
them at nighttime and it was fine.

457
00:22:15,912 --> 00:22:16,932
And noise.

458
00:22:16,962 --> 00:22:21,332
Noise is another one that can trigger
off epilepsy in dogs and cats.

459
00:22:21,842 --> 00:22:23,732
And it's often not the
kind of noises you'd think.

460
00:22:23,732 --> 00:22:27,782
I'm not talking loud banging
noises,I'm talking subtle noises.

461
00:22:27,782 --> 00:22:30,842
And in cats in particular, it can be keys.

462
00:22:30,872 --> 00:22:31,667
The jangling of

463
00:22:31,667 --> 00:22:31,777
keys

464
00:22:31,777 --> 00:22:33,352
Dr Emma Hancox: Oh, Or the
rustling of something or...

465
00:22:33,362 --> 00:22:36,252
Dr Mark Lowrie: You've got it, and
banging a fork against a ceramic bowl.

466
00:22:36,252 --> 00:22:36,402
What?

467
00:22:36,402 --> 00:22:40,332
Banging is a strong word, gently
tapping would trigger these things.

468
00:22:40,332 --> 00:22:41,892
So there are definitely,

469
00:22:41,992 --> 00:22:43,472
Dr Emma Hancox: I wonder
whether it's to do with sound

470
00:22:43,522 --> 00:22:44,672
waves or something like that?

471
00:22:44,892 --> 00:22:47,482
Dr Mark Lowrie: And in cats it's
fascinating 'cause it's older cats

472
00:22:47,482 --> 00:22:52,282
that tend to get it usually in the
second decade of life and half of

473
00:22:52,287 --> 00:22:55,312
the cats that get this are actually
deaf, which is unbelievable.

474
00:22:55,317 --> 00:22:57,007
Dr Emma Hancox: That's,
even more remarkable.

475
00:22:57,637 --> 00:22:58,897
This is blowing my mind, Mark.

476
00:22:58,897 --> 00:22:59,527
I'm not gonna lie!

477
00:23:00,142 --> 00:23:02,752
Dr Mark Lowrie: It blew my mind
and I can't explain it, but I think

478
00:23:02,752 --> 00:23:05,992
sometimes it is, there's, it's the
frequency of the sound in particular.

479
00:23:05,997 --> 00:23:09,562
So it's not shouting or
being loud that's triggering.

480
00:23:09,567 --> 00:23:13,302
It's a subtle sound that may be still
the wavelength is such that it's

481
00:23:13,302 --> 00:23:15,252
still detected in these deaf patients.

482
00:23:15,252 --> 00:23:17,532
But yeah, it's a real can of worms.

483
00:23:17,532 --> 00:23:21,432
Some of these seizure triggers and it
comes back to that really awful answer

484
00:23:21,432 --> 00:23:25,247
of we don't know, but if an owner knows,
we don't know, we're being honest.

485
00:23:25,392 --> 00:23:28,902
We're being open, we're being honest,
and I think that's really vital to help

486
00:23:28,902 --> 00:23:33,402
that relationship and help work through
the difficult situation of epilepsy.

487
00:23:34,317 --> 00:23:37,197
Dr Emma Hancox: And so how often,
again, something I see on these Facebook

488
00:23:37,197 --> 00:23:43,052
groups is, how has anyone been able to
find a trigger for their pets seizure?

489
00:23:44,232 --> 00:23:47,157
How often do you think
that we'll find those?

490
00:23:47,157 --> 00:23:50,847
I know that's really difficult to
try and put a number to, but do

491
00:23:50,847 --> 00:23:53,727
you think owners should be like,
I get the feeling some of them are

492
00:23:53,727 --> 00:23:58,437
fixated sometimes on trying to find a
trigger or a cause for that seizure.

493
00:23:59,517 --> 00:24:03,147
I was under the impression most
of them are just spontaneous.

494
00:24:03,147 --> 00:24:06,777
We don't know when they're going to happen
unpredictable, but perhaps there are some

495
00:24:06,777 --> 00:24:10,317
triggers in some, could you put a number
to those or is that really difficult?

496
00:24:10,752 --> 00:24:13,752
Dr Mark Lowrie: A number is hard,
but I think it's fair to say it's

497
00:24:13,782 --> 00:24:15,522
really rare we find a trigger.

498
00:24:15,642 --> 00:24:17,432
Now, I don't think that's
because we're not looking.

499
00:24:18,477 --> 00:24:19,437
Owners are very good

500
00:24:19,437 --> 00:24:24,087
at noting when the fits were, seeing
if there's a relationship with

501
00:24:24,087 --> 00:24:28,497
feeding, with activity, with time
of day, and I'd encourage them to do

502
00:24:28,497 --> 00:24:31,647
that because sometimes it does allow
us to find out what's happening.

503
00:24:32,217 --> 00:24:36,927
A great case I can think of that I saw
a number of years ago now was a dog that

504
00:24:36,927 --> 00:24:41,877
always had a fit at half past seven on
a Thursday morning, every week reliably.

505
00:24:42,567 --> 00:24:43,747
So there's a clear pattern.

506
00:24:44,577 --> 00:24:45,127
But why?

507
00:24:45,317 --> 00:24:47,917
And so the owners didn't know why at all.

508
00:24:47,977 --> 00:24:49,297
We treated the dog with medication.

509
00:24:49,297 --> 00:24:52,697
It didn't seem to make any
difference, but then they moved house.

510
00:24:53,567 --> 00:24:57,522
And when they moved house, it happened
at 10 o'clock on a Tuesday morning

511
00:24:58,002 --> 00:24:58,712
and it was always

512
00:24:58,712 --> 00:25:00,722
Dr Emma Hancox: I feel it's
the binmen or something that.

513
00:25:00,722 --> 00:25:01,622
Dr Mark Lowrie: How did you know?

514
00:25:01,622 --> 00:25:03,862
Dr Emma Hancox: I just was trying to think
of something that happened every week.

515
00:25:03,862 --> 00:25:05,552
Sorry, I’ve taken your thunder away there.

516
00:25:05,852 --> 00:25:06,692
Dr Mark Lowrie: No, fantastic.

517
00:25:06,692 --> 00:25:07,592
But it's things like that.

518
00:25:07,592 --> 00:25:10,172
So it was, it's, the bin
men arrived at the house.

519
00:25:10,172 --> 00:25:12,452
It was stressful for the
dog and it triggered a fit.

520
00:25:12,632 --> 00:25:14,972
So silly things like that.

521
00:25:15,032 --> 00:25:17,112
And, it's, it was only the
move of house that made them

522
00:25:17,112 --> 00:25:18,672
realise there is something here.

523
00:25:18,672 --> 00:25:20,562
What's the same in both situations.

524
00:25:20,592 --> 00:25:21,702
It's clearly not time of day.

525
00:25:21,707 --> 00:25:23,252
There's something happening
at time of the day.

526
00:25:23,312 --> 00:25:24,752
Dr Emma Hancox: How are
they ever gonna avoid that?

527
00:25:24,752 --> 00:25:26,702
They're just gonna have to
put their bins somewhere else.

528
00:25:26,772 --> 00:25:28,882
Dr Mark Lowrie: They had to go
to the tip themselves, just just

529
00:25:28,882 --> 00:25:29,982
go and, empty their own bins

530
00:25:29,982 --> 00:25:31,302
Dr Emma Hancox: Oh, the
things we do for our dogs.

531
00:25:33,942 --> 00:25:37,842
This is all really great
information, but I'm just wondering

532
00:25:37,842 --> 00:25:39,042
how we're ever gonna do this.

533
00:25:39,282 --> 00:25:41,592
Going back to the very beginning,
how we're gonna do it in such

534
00:25:41,592 --> 00:25:44,652
a short consultation time, what
are the kind of key points that

535
00:25:44,657 --> 00:25:45,522
you would want to bring out?

536
00:25:46,017 --> 00:25:48,237
Dr Mark Lowrie: So when you've got the
owner in the consult and you've got a

537
00:25:48,242 --> 00:25:52,707
very short period of time, there are
key points you always have to mention.

538
00:25:52,917 --> 00:25:56,307
And it doesn't matter who the
owner is, what the dog's doing.

539
00:25:57,147 --> 00:25:58,617
I think it's important
to bring these across.

540
00:25:58,617 --> 00:26:01,017
Now you could provide this in
a resource somewhere, a little

541
00:26:01,017 --> 00:26:04,947
leaflet, a downloadable, PDF
what whatever the owners need.

542
00:26:05,967 --> 00:26:09,507
For me, I’ve said it already, but the
number one thing is to say epilepsy

543
00:26:09,507 --> 00:26:11,427
is a chronic progressive disorder.

544
00:26:11,847 --> 00:26:13,767
These dogs aren't going to be fixed.

545
00:26:14,217 --> 00:26:18,957
We will talk about medication later on,
but medication, and we're all guilty of

546
00:26:18,957 --> 00:26:21,152
it, we tend to use the word treatment

547
00:26:21,347 --> 00:26:22,997
Dr Emma Hancox: Yes, I'm
guilty of that for sure

548
00:26:23,492 --> 00:26:25,412
Dr Mark Lowrie: When we say
we're treating epilepsy.

549
00:26:25,802 --> 00:26:29,252
I personally feel, if I was an owner
listening to a vet telling me they're

550
00:26:29,252 --> 00:26:32,537
going to treat my dog's epilepsy,
that I'm gonna somehow get a cure.

551
00:26:32,927 --> 00:26:33,747
Dr Emma Hancox: Or you’re gonna fix it.

552
00:26:34,217 --> 00:26:36,077
Dr Mark Lowrie: We're gonna
fix it and we can't fix it.

553
00:26:36,617 --> 00:26:39,707
So it's important to use, I try
and use the word management.

554
00:26:40,127 --> 00:26:42,587
I think it's a more appropriate
term, it's more understandable

555
00:26:42,947 --> 00:26:46,907
and it sets expectations, but
epilepsy is going to continue.

556
00:26:47,477 --> 00:26:52,747
So the aim of managing seizures with
medication is not to cure the seizures.

557
00:26:53,197 --> 00:26:55,727
It's to try and get them
under some form of control.

558
00:26:56,477 --> 00:26:58,547
A quick fix is really unlikely.

559
00:26:59,207 --> 00:27:02,957
And an owner will have to expect to
have fairly frequent visits to the

560
00:27:02,957 --> 00:27:05,307
vet to get some modicum of control.

561
00:27:05,452 --> 00:27:06,182
That's really important.

562
00:27:06,722 --> 00:27:09,092
Dr Emma Hancox: It's not just gonna be
a course of medication and then stop.

563
00:27:09,482 --> 00:27:11,812
Dr Mark Lowrie: No, and I’ve
known that, dogs will be given,

564
00:27:11,917 --> 00:27:13,142
prescribed, phenobarbital.

565
00:27:13,262 --> 00:27:16,442
They'll go away for two weeks with
a two week course of phenobarbital.

566
00:27:17,222 --> 00:27:20,672
And because the owner hasn't understood,
it's not the, it's not the vet's fault,

567
00:27:20,672 --> 00:27:23,992
it's because probably that owner was very
stressed in the moment they've done it

568
00:27:24,062 --> 00:27:25,682
two weeks, they've stopped the medication.

569
00:27:26,417 --> 00:27:29,207
Then we know what goes on then,
we get withdrawal seizures,

570
00:27:29,477 --> 00:27:30,797
the whole situation gets worse.

571
00:27:31,187 --> 00:27:34,067
So owners need to know any
medication you give is life long.

572
00:27:35,207 --> 00:27:38,447
I think it's also important to
say that adverse effects from the

573
00:27:38,447 --> 00:27:40,027
medication are really, really common.

574
00:27:40,707 --> 00:27:45,407
So all antiepileptic medication,
despite what anybody says, will

575
00:27:45,407 --> 00:27:47,747
have some form of side effect.

576
00:27:48,287 --> 00:27:51,527
Now, hopefully that's mild and
it's tolerable to the owners

577
00:27:51,557 --> 00:27:52,717
and it's tolerable to the dog.

578
00:27:53,567 --> 00:27:56,387
But we know that there are some dogs
that are a bit more susceptible to

579
00:27:56,387 --> 00:27:57,857
those adverse effects than others.

580
00:27:58,577 --> 00:28:01,727
And if you've got a dog with loads
and loads of fits, owners will

581
00:28:01,727 --> 00:28:04,767
tolerate more side effects than those
dogs that maybe just have one fit

582
00:28:04,792 --> 00:28:07,107
every 6 to 12 weeks so it varies a lot.

583
00:28:07,177 --> 00:28:10,277
So owners need to know
that sort thing too.

584
00:28:10,567 --> 00:28:15,727
And I think making sure owners
know not to stop medication

585
00:28:15,777 --> 00:28:17,467
suddenly in any circumstance.

586
00:28:17,947 --> 00:28:21,087
You can stop medication, but it really
needs to be done under veterinary

587
00:28:21,087 --> 00:28:24,417
guidance and carefully and ideally slowly.

588
00:28:24,867 --> 00:28:27,597
There will be situations when it
needs to be stopped suddenly, if

589
00:28:27,597 --> 00:28:30,957
there are terrible adverse effects,
life-threatening, adverse effects.

590
00:28:31,317 --> 00:28:32,097
But that's really rare.

591
00:28:32,537 --> 00:28:34,977
Phenobarbital is a very safe medication.

592
00:28:35,367 --> 00:28:37,197
I think it's got a lot of bad press.

593
00:28:37,707 --> 00:28:40,937
I say, vets seem to, I'm
gonna include myself in this.

594
00:28:41,597 --> 00:28:44,297
I'm quite happy to give out
steroids quite frequently.

595
00:28:44,297 --> 00:28:45,707
I'm a neurologist, that's what I do.

596
00:28:46,997 --> 00:28:47,778
So steroids are

597
00:28:47,793 --> 00:28:51,183
given out frequently and almost,
dare I say it, like sweets.

598
00:28:51,663 --> 00:28:54,453
Whereas phenobarbital, people are
a lot more reserved and concerned

599
00:28:54,453 --> 00:28:58,083
by, I dunno why, because I feel
phenobarbital is much safer medication.

600
00:28:58,188 --> 00:28:58,668
Dr Emma Hancox: It's so true.

601
00:28:58,668 --> 00:29:03,088
I’ve never thought about it like that, but
I'm nodding my head vigorously over here,

602
00:29:04,633 --> 00:29:07,248
Dr Mark Lowrie: So I think it's important
for vets to understand that yes, they

603
00:29:07,248 --> 00:29:08,838
are worried prescribing phenobarbital.

604
00:29:09,143 --> 00:29:13,313
due to its safety profile, but actually
it's much, much better than other

605
00:29:13,523 --> 00:29:15,473
routinely used medications in practice.

606
00:29:15,473 --> 00:29:17,663
I'd want to make that
point so people are aware

607
00:29:18,283 --> 00:29:18,793
Dr Emma Hancox: Perfect.

608
00:29:19,203 --> 00:29:23,413
And I think actually we're gonna pick
up on, measurements and management

609
00:29:23,413 --> 00:29:27,193
of things like that of phenobarbital
in our next episode as well.

610
00:29:27,193 --> 00:29:27,803
I think.

611
00:29:27,933 --> 00:29:28,613
Dr Mark Lowrie: I can't wait.

612
00:29:28,843 --> 00:29:29,263
Dr Emma Hancox: I know.

613
00:29:29,323 --> 00:29:29,833
Same.

614
00:29:30,293 --> 00:29:31,043
Thank you Mark.

615
00:29:31,103 --> 00:29:34,133
I think that's probably all we've
got time for in this first episode,

616
00:29:34,133 --> 00:29:37,823
but it has been really great speaking
with you and finding out what we can

617
00:29:37,828 --> 00:29:39,443
learn from the, from these experts.

618
00:29:39,773 --> 00:29:42,863
Hopefully our listeners have found it
as fascinating as I have, those triggers

619
00:29:42,863 --> 00:29:45,983
that we were talking about, it's really
fascinating for me and please tune into

620
00:29:45,988 --> 00:29:49,763
our next episode where we were moving
on to the second instalment of the

621
00:29:49,763 --> 00:29:51,203
S.M.A.R.T Approach, which is Measure.

622
00:29:51,203 --> 00:29:54,833
So hopefully we can pick back up
that conversation that we maybe

623
00:29:54,833 --> 00:29:58,613
just alluded to, where it comes to
phenobarbital, adverse effects and

624
00:29:58,613 --> 00:30:00,173
monitoring and things like that as well.

625
00:30:00,623 --> 00:30:03,563
Obviously, we'll be joined once again
by Mark to discuss the importance

626
00:30:03,563 --> 00:30:05,473
of, managing our epileptic patients.

627
00:30:05,743 --> 00:30:06,433
Thanks again, Mark.

628
00:30:06,673 --> 00:30:07,288
Dr Mark Lowrie: Thanks, Emma.

629
00:30:07,483 --> 00:30:07,873
Dr Emma Hancox: Thanks.

630
00:30:07,873 --> 00:30:08,323
See you soon.