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Welcome to Oxford Plus, the podcast series
that takes you deep into the myths and

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truths of the Oxford investing landscape.

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I'm your host, Susannah de
Jager, and I've spent over 15

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years in UK asset management.

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My guest today is Dave Norwood.

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Dave graduated from Keeble College,
Oxford, with a degree in modern history

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and went into investment banking.

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He has founded and been a director
of numerous UK technology companies

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including Oxford Nanopore, Proxy
Imogen, Synergen, 4D Pharma, Index

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IT, Evolution Group and Aura Capital.

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Dave is also the founder of IP Group
PLC and Oxford Science Innovation,

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now Oxford Science Enterprises,
the largest university venture

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fund globally, which has brought in
over 1.5 billion of investment into

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Oxford since its inception in 2015.

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Dave is also a grandmaster in chess
and has represented both England

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and Andorra internationally.

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Without Dave, much of the investment
landscape of Oxford would not look

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how it does today, and so I'm looking
forward to hearing his thoughts

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and predictions as to what will and
should change over the next 10 years.

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Dave, thank you so much for joining today.

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You're very welcome.

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It's nice to be here.

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Wonderful.

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So, going back a few
years now, you set up OSI.

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I'd love to know what it was
you identified that precipitated

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the need to set up OSI, Oxford
Science Innovation, as it then was.

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That's a good question, sadly
we'll have to go back a few more

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years, I'm actually quite old.

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So probably better we start
further back because it then

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will hopefully make more sense.

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It really goes back to when I arrived
at Oxford a long time ago, 1988, and

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I read history, everyone assumes I
read chemistry but I read history,

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chemistry was too difficult for me.

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I was surprised when I saw that.

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I'll be honest, I'm one of those people.

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Yeah.

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I did sort of make friends with
quite a few sort of scientists,

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particularly when I also have a
background in chess and most chess

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players are good at maths or science.

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So again, they don't tend to be historians
and I kind of kept in touch with these

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people after I'd left Oxford, and I sort
of stumbled into the world of finance,

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so I really didn't know what I was doing.

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I didn't really want to
do it, if I'm honest.

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But what interested me was going back
to Oxford, seeing my friends who were

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going to do these research projects in
various areas, and more and more, you

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know, we'd be in the pub and I'd be
like, so what are you planning to do?

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Oh, I want to build this machine, or I've
got this idea for a computer game, or...

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and I just love to hear their
stories and then they'd be like,

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well, if only we could find £50,000,
we could build a prototype and

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so I'm like, well, you know what?

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And I've always been
a reasonable salesman.

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So I sort of went.

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and got some of the rich people I knew
to just, in finance to put some money

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into these early ideas in Oxford.

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So it was a complete accident and
they didn't even go particularly well.

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But you know, I remember one
guy introducing me to his tutor.

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He said, my tutor can't believe
you've raised this money.

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He wants to, he really wants to meet you.

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So I met him and he was a sort of very
eminent professor and then he started

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telling me more and more stories and
about ideas in Oxford that there were

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and he invited me to a dinner and it was
actually a seminal moment in my life.

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I got invited to a dinner and I'm going
back now to probably about 1997 and it's a

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very odd story actually because a few days
before I actually got bitten by a snake.

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That is not what I expected you to say.

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Yeah, I know, that was it.

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What kind of snake?

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Yeah, it was an adder, I'd been for lunch
in the Ashdown forest with a couple of

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friends and we'd gone for a walk after.

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That's spectacularly unlucky.

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Well, it wasn't unlucky because I saw
this adder and I was fascinated by

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snakes, so I gently trod on its tail.

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Yeah, looking back it was a silly thing
to do, but I gently trod on its tail

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and then started stroking its neck.

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No you didn't!

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I did, and then it turned around and bit
me, and it was pretty horrific because

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the blood sort of spurted out, but I
thought it was a grass snake anyway,

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so I wasn't particularly worried, it
was only when my arm started to throb.

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Anyway, we went back to the hotel
where we'd had the lunch and I told

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them I'd been bitten why one of the
snakes in their garden and the guy

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went paler than me and they rang for
an ambulance and rushed me to hospital.

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I literally nearly died because
I had a terrible reaction,

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spent almost a week in hospital.

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So I got out of hospital
and I had my arm in a sling.

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So this professor had actually invited
me to a High Table lunch at Queen's

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and I was ringing him to say I can't
go, I've been bitten by a snake and

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I'm still not feeling very well, and
I rung him and he was like, Oh, I'm so

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pleased you rang me, you're going to
meet this professor who's brilliant,

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he's an amazing inventor, he'd love to
meet you and  I didn't have the heart

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to say, well, actually I'm not coming.

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So I thought well sod it, I'll
just go, right, how bad can it be?

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As usual, like really enjoying myself,
we had a lovely meal at High Table,

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lots of nice wine and then port and
anyway, I was with my friend who's

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Professor Pete Dobson, who actually
built Begbroke really, was his project.

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But he introduced me to this
lovely old guy called Professor

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Alan Hill, who obviously noticed
that my arm was in a sling.

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So I told him the story of the snake and I
thought, what's odd is I thought I'd have

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built some kind of immunity to being...

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I've been bitten by like lots of things
like mosquitoes and stuff in my life and

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he goes, no, it's the opposite, you know?

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And so I learned, Oh, you must be a
chemist and you know, so he then started

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telling me his story and his story
was unbelievably romantic and truly

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inspirational and he told me about this
idea he'd had years and years ago, that

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a way to sort of measure blood sugar
levels and a bit of me being nice, I

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said so what's that useful for you know?

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And he goes, well it's funny you
say that, at first that was my

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thought, what is it useful for?

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He said well it became useful when
we realised that with a sort of tiny

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prick of someone's finger, you know,
you take a tiny amount of blood and

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you can see what the glucose level is.

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Which actually became a product
which has revolutionised diabetes.

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So if you know any diabetics, their lives
have been transformed by the ability to

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self test and it all came from Professor
Alan Hill's idea all those years ago

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and I remember hearing about it and
I'm like, oh, that sounds interesting.

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Why don't we create a company out of it?

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And he said, well actually, he's a very
modest bloke, he said, well I would

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have loved to have done that, but we
did create a company and we just sold

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it for $890 million and I was like,
wow, and he said, well it's interesting

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though, like, you know, no one in the
UK was particularly interested in it.

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It was as usual, a US company and
you know, I'm like yeah, and I

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said well there's probably a lot
of ideas like that in Oxford and he

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goes, you just wouldn't believe it.

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There were so many amazing ideas
that could change the world, change

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people's lives and even make money.

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But actually he wasn't driven by
the money, he was driven by the fact

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that literally, you know, hundreds of
millions of people now around the world

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have had their lives improved by...

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and that in some ways was the beginning
of sort of self diagnostics, you know,

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what we all got used to during COVID.

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A lot of it can be traced back to Alan
Hill and the chemistry department.

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So, at least it gives you context as
to why I was really interested and I

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carried on doing, helping sort of spin
outs from Oxford on an ad hoc basis,

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until I found out that they were trying
to build a new chemistry department.

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So this is all at the end of
the 90s and they'd raised a lot

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of money from charities, the
Wellcome Trust, the government.

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But they were trying to build this brand
new, they wanted to build like the most

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modern chemistry department in the world.

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Oxford Chemistry is ranked top in
the world and they thought we need a

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building that just looks fantastic.

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But they were £20 million short.

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So they came to me and said Dave,
you're good at raising money.

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We've seen you raise money
for these little companies.

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Why don't you raise us the
20 million pounds to help us

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do the chemistry building?

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So this is 1999 and I said, well
what about, what do I get in return?

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And they looked at me as if like, well,
you don't know what you thought of that.

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I said, well, here's an idea.

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Why don't, in return for these £20
million, we would like to have a stake

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in all the ideas that come out of that
department forever and they're like,

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well, forever's a very long time.

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That's not going to work.

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So we hammered out a long, interesting
deal, which was basically, we would

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share 50 50 with the university, the
stakes in the ideas that came out for

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the next 15 years and we finally did
the deal in 2000, to go and raise £20

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million and it meant Oxford were happy
because they got to build the state of

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the art chemistry department which is
still there on South Parkes Road and we

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then had 15 years to try and turn some of
the ideas into something that works and

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hopefully recoup that 20 million pounds
and that was the beginning of IP group.

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That was how IP group started
and it was a very unusual deal.

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It's the first deal of its
kind and over those 15 years,

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I've got to be honest, right?

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There was lots of times where I thought,
my God, this is the most stupid deal.

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Why on earth have I done this?

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And I realised that if I just sort of
sat there and waited for the ideas to

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come, they probably weren't going to come
and I wasn't going to get my money back.

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So I sort of moved back to Oxford and
I literally spent every day, whether it

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was taking a scientist to the coffee shop
or dragging them over to the pub to hear

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their ideas in the chemistry department
because I thought we've really got to

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work hard to make that stuff see the
light of day and conveniently, when that

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ended, the IP group deal ended in 2015,
by this time I was long retired, right?

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My friends were still running IP
group, I'm sure you've met them,

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but I'd long retired, I was still in
touch with them, but only for catching

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up over coffee or a glass of wine.

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Oxford was saying, we've noticed that In
that 15 years, more ideas have come out

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of the chemistry department, pretty much
all the other departments put together.

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What was, why was that?

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And I'm like, well because we cared,
we really had to try and make it work.

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So that was how the idea of
Oxford Sciences came about.

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It wasn't my idea, it was really a
continuation of an idea that we'd all

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sort of had all those years ago and Oxford
said you know what, why don't we try and

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do this experiment with every department?

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So, we partner with Oxford, so rather
than an IP group, which obviously has done

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deals with lots of universities, we just
want our own private commercialisation

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vehicle, which we called OSI, it's now
called OSE, or Oxford Science Enterprises

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and then we said, right, we're not going
to go out and raise 20 million this time,

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we're going to be really ambitious and in
the end, well, in total, we've probably

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raised about a billion and Oxford has got
the biggest, in effect, dedicated fund or

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whatever you want to call it in the world.

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But again, with the same mission that
goes back to that amazing dinner I

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had after I'd been bitten by a snake,
which is find brilliant scientists

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who've got ideas that can change the
world and help them do it, right?

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And so in effect, lots has
changed, but nothing has changed.

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That's really what we're trying to do.

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Yeah that's exceptionally clear,
particularly the snake bite.

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So that completely resonates with what
arguably one still sees a lot of today.

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So my question to you would be, you
know, we still see a lot of companies,

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arguably at the stage you're talking
about, still being sold to the US so,

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we've got OSE and similar funds around
the UK now that have emulated the same

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sort of structure and they're functioning
really well and yet, it still seems to be

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the normal course, not without exception,
Oxford Nanopore being an example, but

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that most companies ultimately end up
needing to take US money or listing on

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the NASDAQ as a sort of default playbook
and so, do you with your experience,

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see anything additionally that we can do
to change that as it's still evolving?

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And I'll ask a different question
later rather than lead the witness.

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Yeah, no, it literally is the key
question for me that I've wrestled

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with all of my life, what you've asked
me, and I don't have the answers.

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I still think it's a great shame that the
UK still does have incredible ideas and

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yet we do not have the capital to allow
the best of those ideas to go forward and

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it's no use trying to pretend that we have
and I've met with Prime Ministers, I've

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met with different governments, every side
of the political spectrum, and they all

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recognise that they've got to do something
about it and say they're going to do

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something about it, but somehow something
happens It doesn't happen , so...

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I don't know what you're talking about
Dave, I've never experienced this!

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Must be some other government!

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You know, they're all the same to me.

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Nothing ever happens and it is kind
of tragic and I think because of that

216
00:12:53,645 --> 00:12:57,464
there isn't this belief that can sort
of break this glass ceiling, you know...

217
00:12:57,714 --> 00:12:59,055
It's self fulfilling.

218
00:12:59,915 --> 00:13:01,898
Yeah.

219
00:13:01,898 --> 00:13:05,704
I'm not of the mindset which is like,
selling these companies to Americans

220
00:13:05,704 --> 00:13:09,604
or the Chinese or it's necessarily
a bad thing because what it does do

221
00:13:09,604 --> 00:13:14,224
is it recycles capital, it's a great
learning experience, it's a great sort

222
00:13:14,224 --> 00:13:15,974
of role model for people to do, right?

223
00:13:15,974 --> 00:13:20,024
Well, they sold for $500 million,  we
can do one better and sell for a billion.

224
00:13:20,034 --> 00:13:24,494
So it's not all bad, and also when
companies get bought, you know, you get

225
00:13:24,494 --> 00:13:26,074
your second generation entrepreneurs.

226
00:13:26,074 --> 00:13:30,674
I mean, one young lad,  I'm not going
to name him, one young lad who came

227
00:13:30,674 --> 00:13:34,464
to work for me, you know, made a
hundred million dollars from his spin

228
00:13:34,464 --> 00:13:41,819
out and you know, so he has created
a sort of role model here in Oxford

229
00:13:42,010 --> 00:13:43,839
for someone who can do that, right?

230
00:13:43,890 --> 00:13:47,779
You know, in my day, the only way you
could become rich was to go into the city.

231
00:13:47,810 --> 00:13:52,380
So to me, I'm a historian, so I see things
in a very different, and these things

232
00:13:52,380 --> 00:13:56,419
don't necessarily move fast, you know,
it's not a, but yeah, the government

233
00:13:56,429 --> 00:14:02,945
still doesn't really do enough, we know
that, and it will talk a good game, and

234
00:14:03,025 --> 00:14:06,805
if they are serious, and we, you know,
whatever we are post Brexit, we want

235
00:14:06,805 --> 00:14:10,835
to be an IP based economy, we really
have to do some urgent work, right?

236
00:14:11,495 --> 00:14:15,274
And like you say, you know, UK pension
funds, I've talked about it, I've sat

237
00:14:15,274 --> 00:14:19,419
on the patient capital review, and
they're still not investing anything

238
00:14:19,430 --> 00:14:23,129
like the amount we need to see this
stuff work and if we don't make this

239
00:14:23,139 --> 00:14:25,519
stuff work, what has the UK got?

240
00:14:25,520 --> 00:14:28,950
You know, there's a bit like, it's nice
to do this stuff because it's really

241
00:14:28,950 --> 00:14:33,169
important to do things like cancer and we
saw the impact of the COVID vaccine that

242
00:14:33,169 --> 00:14:36,000
came out of Oxford, which was amazing.

243
00:14:36,020 --> 00:14:38,549
I was so sort of proud to be
involved in that in a small way.

244
00:14:39,160 --> 00:14:41,220
So, you know, these things
are incredibly important.

245
00:14:41,250 --> 00:14:46,230
They're also the future of our economy
and you know, even AI, I mean, you know,

246
00:14:46,260 --> 00:14:50,490
AI, we could have an amazing role in the
AI world because Oxford is becoming a

247
00:14:50,490 --> 00:14:55,380
hub for AI ideas and I worry that we're
going to miss that opportunity too.

248
00:14:56,440 --> 00:15:00,339
And in your interactions with government,
when you've gone and sort of pleaded

249
00:15:00,339 --> 00:15:04,030
the case, what do you think the best
intervention would be that they could do?

250
00:15:04,220 --> 00:15:07,760
So I think there's actually two
really important things and to

251
00:15:07,760 --> 00:15:10,820
some extent they're separate and
to some extent they're connected.

252
00:15:11,710 --> 00:15:15,710
So I've looked at lots of US companies,
obviously, you know, people quote

253
00:15:15,850 --> 00:15:17,800
so many success stories in the US.

254
00:15:18,170 --> 00:15:20,199
What's interesting about a
lot of them is that they...

255
00:15:20,299 --> 00:15:24,700
their first customers were actually
government departments, or some

256
00:15:24,739 --> 00:15:28,810
kind, like, you know, so this
happens, and the Americans know how

257
00:15:28,810 --> 00:15:32,175
to build companies, that's one thing
we can't deny they do well, right?

258
00:15:32,545 --> 00:15:35,805
But a lot of them get this amazing
headstart where if they're doing

259
00:15:35,805 --> 00:15:39,505
something really well, the government
falls over itself to make sure that

260
00:15:39,505 --> 00:15:42,074
kind of, I won't call it soft money
because they've got it, but it goes

261
00:15:42,095 --> 00:15:45,005
to them and they get their first
customers so they can prove it works.

262
00:15:45,105 --> 00:15:50,054
They can get money and scale up and
it gives investors confidence and

263
00:15:50,054 --> 00:15:54,520
actually, you know, just even in areas
like genomics where I've worked a lot,

264
00:15:54,540 --> 00:15:58,089
obviously, I was chairman of Oxford
Nanopore in the early days, like you

265
00:15:58,089 --> 00:16:00,369
know, the government come and see us
and say yeah, we really want to help,

266
00:16:00,379 --> 00:16:02,219
but could we get contracts out of them?

267
00:16:02,349 --> 00:16:08,090
So to me, you know, the NHS is this
unbelievable resource, but how much

268
00:16:08,090 --> 00:16:11,379
does it really help UK startups?

269
00:16:11,419 --> 00:16:12,949
It just is impossible.

270
00:16:13,310 --> 00:16:18,689
So all this kind of value and where
we could make a difference to how

271
00:16:18,709 --> 00:16:22,124
we don't and it's kind of weird,
we'd almost rather give contracts

272
00:16:22,124 --> 00:16:23,734
to US companies than our own.

273
00:16:23,825 --> 00:16:26,565
And by the way, you don't have
to spend money to do that.

274
00:16:26,994 --> 00:16:29,885
I feel like that's an important memo
to anyone in government listening.

275
00:16:30,464 --> 00:16:31,904
This won't cost you money.

276
00:16:32,365 --> 00:16:33,685
This is a free solution.

277
00:16:35,785 --> 00:16:40,114
it's almost like they're embarrassed
to give it to their own, which

278
00:16:40,354 --> 00:16:43,454
like bit of like benign
nepotism would be a bad thing.

279
00:16:43,524 --> 00:16:46,645
Well, the Americans have no qualms
about it and obviously now they're

280
00:16:46,645 --> 00:16:49,505
like, well we won't even give
anything to China or anywhere else.

281
00:16:49,515 --> 00:16:53,644
So like, so they have no qualms
about backing their right?

282
00:16:53,644 --> 00:16:56,985
Because they believe in ideas, they
see the ideas create the world, right?

283
00:16:57,004 --> 00:17:01,205
So it's like, so that
frustrates me, right, so that...

284
00:17:01,655 --> 00:17:05,365
and maybe if people saw that the
government was more behind that, it'd be

285
00:17:05,405 --> 00:17:09,295
easier to for instance, for pension funds
to say right, we're now going to commit

286
00:17:09,305 --> 00:17:15,684
10 percent say, to UK startups because
we know, but you almost can't blame them

287
00:17:15,685 --> 00:17:17,964
at times saying, well we don't want to
commit money because they're never going

288
00:17:17,964 --> 00:17:19,275
to be given a chance by the government.

289
00:17:19,334 --> 00:17:22,385
You know it becomes this vicious
cycle that needs to be broken.

290
00:17:22,635 --> 00:17:25,585
So, you know, sorry, I
feel I'm rambling a bit...

291
00:17:25,585 --> 00:17:27,134
I think it's spot on.

292
00:17:27,134 --> 00:17:31,795
In 30 years, I've created probably
more spin outs than anyone ever and

293
00:17:31,795 --> 00:17:34,565
that sounds like a boast and it's not
because most of them have gone wrong.

294
00:17:35,415 --> 00:17:38,695
But I would say if at critical
moments we could have accessed the

295
00:17:38,695 --> 00:17:44,425
contract, whether it's from even the
Ministry of Defence or the, you know,

296
00:17:44,495 --> 00:17:46,025
would have been transformational.

297
00:17:46,150 --> 00:17:49,840
And it's not a flat playing field and
that, you know, in my conversations,

298
00:17:49,889 --> 00:17:54,679
much shorter dated rather than yours
with government, it was a bit bizarre

299
00:17:54,719 --> 00:17:57,290
that you almost had this conversation
where they'd say, oh, well, you know, we

300
00:17:57,290 --> 00:18:00,300
think it's a private sector problem and
you'd say, but it's not and the playing

301
00:18:00,300 --> 00:18:05,090
field isn't even, and Silicon Valley,
lest we forget, was a defense project and

302
00:18:05,090 --> 00:18:09,909
basically still is and the IRA, they're
just pumping money into, you know, all of

303
00:18:09,909 --> 00:18:14,190
these spinouts and by the way, poaching
some of ours because great tax breaks and

304
00:18:14,190 --> 00:18:18,975
you do go, to your point, if this is our
plan, and we've you know, kind of slightly

305
00:18:19,025 --> 00:18:24,215
ditched financial services for want of a
better expression, we do need to realize

306
00:18:24,264 --> 00:18:28,144
that we've got to fight for it, and that
we're not just going to automatically

307
00:18:28,184 --> 00:18:29,435
be given a seat at the table.

308
00:18:29,445 --> 00:18:35,449
Exactly, exactly, and to me it's
slightly heartbreaking because that's

309
00:18:35,449 --> 00:18:38,659
all I've done with my life and we,
you know, I'm not complaining, we've

310
00:18:38,659 --> 00:18:43,540
had some nice success stories and I'm
not starving just yet, but I would

311
00:18:43,540 --> 00:18:45,899
have loved to have seen more impact.

312
00:18:46,069 --> 00:18:49,665
But they all talk the talk, it
doesn't matter whether you're

313
00:18:49,775 --> 00:18:51,425
Labour or Conservative or whoever.

314
00:18:51,695 --> 00:18:55,684
They all say that this is what they want
to see and to be fair, there's been some

315
00:18:55,684 --> 00:18:58,425
good things like VCT, EIS and stuff.

316
00:18:58,445 --> 00:19:00,865
There's been these things
are really great but...

317
00:19:00,865 --> 00:19:02,595
Nothing moving the needle
higher up the scale.

318
00:19:02,675 --> 00:19:03,595
You've got it.

319
00:19:03,935 --> 00:19:07,585
we can set these things up, but you
know, you then want to get to that

320
00:19:07,585 --> 00:19:09,575
scale of capital and it's just a desert,

321
00:19:09,775 --> 00:19:10,065
Yeah.

322
00:19:10,395 --> 00:19:14,995
Okay and so coming to, that kind of spin
and we spoke earlier about, you know,

323
00:19:15,045 --> 00:19:18,535
companies further up the spectrum being
bought out by Americans, but something

324
00:19:18,535 --> 00:19:21,734
that I've heard recently from a number
of people I've interviewed and kind of

325
00:19:21,775 --> 00:19:28,020
beyond is this thing of, because that
capital isn't domestic, it's encouraging

326
00:19:28,130 --> 00:19:31,840
a sort of VC playbook that is quite
short term, that's flipping things

327
00:19:32,170 --> 00:19:37,290
and that is actually, again, a self
fulfilling prophecy that means that the

328
00:19:37,290 --> 00:19:42,110
most ambitious companies don't get an
opportunity to really flourish and so

329
00:19:42,119 --> 00:19:45,530
if we want to build another Nanopore,
to use an example you're familiar with,

330
00:19:45,530 --> 00:19:49,879
and quite frankly, everyone is familiar
with, actually that the capital that's

331
00:19:50,390 --> 00:19:54,070
loop that we're in is a dampening
effect and I'd be really interesting

332
00:19:54,070 --> 00:19:58,675
to get your thoughts on that and if
it can be sort of unpicked at all.

333
00:19:58,815 --> 00:20:03,344
And it's actually got harder, I mean,
like, because of geopolitical tensions.

334
00:20:03,855 --> 00:20:08,165
You know, I was just out in Hong Kong
two weeks ago, seeing some old friends,

335
00:20:08,165 --> 00:20:11,155
and when I was last there, it was
like eight years ago before COVID.

336
00:20:11,429 --> 00:20:15,020
and raised a huge amount of money for
Oxford over there and now there's a

337
00:20:15,290 --> 00:20:18,139
feeling from them, they were lovely,
you know, they were delighted to see me

338
00:20:18,139 --> 00:20:20,989
and took me for some great dinners, but
it was a bit like, well, you guys don't

339
00:20:20,989 --> 00:20:22,159
really want to deal with us anymore.

340
00:20:22,330 --> 00:20:24,120
You know, it's so...

341
00:20:24,770 --> 00:20:26,840
We need more domestic
capital for other reasons.

342
00:20:26,840 --> 00:20:28,905
Yeah, so it's a bit like,
well, we can't deal with China.

343
00:20:29,005 --> 00:20:33,815
I got such grief for getting Huawei into
Oxford Sciences, you know, I thought this

344
00:20:33,815 --> 00:20:37,804
was, you know, one of the world's great
big companies and things are, we're all

345
00:20:37,804 --> 00:20:41,164
working well together and then suddenly
it's become a sort of political problem.

346
00:20:41,844 --> 00:20:44,034
and it's all very well, sure,
we can ban China, we can ban

347
00:20:44,044 --> 00:20:45,504
Saudi Arabia, we can ban anyone.

348
00:20:46,150 --> 00:20:47,810
But then where's the money gonna go?

349
00:20:48,100 --> 00:20:53,139
It's not making the life of the
entrepreneurs on the ground any easier.

350
00:20:53,360 --> 00:20:56,699
The scientists and the entrepreneurs were
like, we want to be really ambitious.

351
00:20:56,730 --> 00:20:58,230
Well, where are we going
to get the money from?

352
00:20:58,230 --> 00:21:00,989
Cause the US is tricky.

353
00:21:01,050 --> 00:21:01,920
The US is very tricky.

354
00:21:01,920 --> 00:21:06,930
We know that, you know, they're trying
to get their capital, they do themselves,

355
00:21:07,000 --> 00:21:09,610
they like to invest in their own stuff
and they've done really well at it.

356
00:21:09,640 --> 00:21:12,690
So, you know, they're interested
in ideas to acquire at the right

357
00:21:12,690 --> 00:21:15,490
point, but it's usually so they can
build their big companies bigger.

358
00:21:15,780 --> 00:21:20,099
You know, we've seen Google do this lots
of times with, you know, the deep minds

359
00:21:20,100 --> 00:21:24,860
of the world set up by, one of my oldest
friends them is the expertise is here.

360
00:21:25,040 --> 00:21:28,740
The expertise is in the UK, but you
know is the finance and the ambition

361
00:21:28,740 --> 00:21:30,770
because without the finance, you
know, it's not very well being

362
00:21:30,770 --> 00:21:32,545
ambitious, but if you've not got any...

363
00:21:32,825 --> 00:21:35,780
the analogy is any petrol in
the tank or whatever, you can't.

364
00:21:36,440 --> 00:21:38,690
And these are very long,
hard journeys, right?

365
00:21:38,990 --> 00:21:40,040
They don't happen overnight.

366
00:21:40,409 --> 00:21:45,679
Okay, and so, coming to something that
is changing and, you know, the Mansion

367
00:21:45,679 --> 00:21:50,919
House Compact has been signed by a
number of key DC pensions, defined

368
00:21:50,920 --> 00:21:55,959
contribution pensions, schemes, and many
of the larger players in the insurance

369
00:21:55,959 --> 00:22:00,190
buyout space and indeed lots of the
consultants that advise those pension

370
00:22:00,190 --> 00:22:04,820
funds and they are committing now to
5%, which I appreciate isn't 10%, and

371
00:22:04,820 --> 00:22:08,639
it's certainly not what the Canadians
have in their pension plans at 20%.

372
00:22:08,820 --> 00:22:12,190
But 5 percent is still massive
compared to where we are.

373
00:22:12,190 --> 00:22:13,500
I think it's below 1 percent now.

374
00:22:13,890 --> 00:22:18,119
So there is going to be more pension
capital by 2030 and obviously DC

375
00:22:18,160 --> 00:22:19,330
pension plans will be growing.

376
00:22:19,330 --> 00:22:22,540
So call it that it might be
50, 60 billion, could be more

377
00:22:22,940 --> 00:22:24,180
that's going to be coming in.

378
00:22:24,339 --> 00:22:28,870
How do you see that impacting these
problems and what do you think are

379
00:22:28,870 --> 00:22:31,090
the kind of straight up positives
and what do you think are perhaps

380
00:22:31,090 --> 00:22:34,380
the bear traps that we need to look
out for with that capital coming in?

381
00:22:34,710 --> 00:22:37,620
Well, as you say, it's all about,
you know, if we look at what

382
00:22:37,629 --> 00:22:40,700
happens now, which is virtually
nothing, it will be a quantum leap.

383
00:22:40,970 --> 00:22:45,429
So, like you say, it's not 20 percent
like Canada, but it's still an

384
00:22:45,429 --> 00:22:47,419
enormous figure in the context...

385
00:22:47,885 --> 00:22:49,065
Of a depressingly low one.

386
00:22:49,065 --> 00:22:50,174
Exactly.

387
00:22:50,185 --> 00:22:55,235
Still, no, I mean, you know, with
those kinds of figures, we could

388
00:22:55,605 --> 00:22:57,635
create some amazing companies.

389
00:22:58,105 --> 00:23:01,185
I think, again, this will all
be a little bit controversial.

390
00:23:01,244 --> 00:23:03,885
We have to be careful and
we've got to be honest.

391
00:23:04,345 --> 00:23:08,080
So, IP Group went and did deals with,
you know, all the universities pretty

392
00:23:08,080 --> 00:23:11,120
much, you know, it was one thing that I
probably had a dozen universities signed

393
00:23:11,120 --> 00:23:13,560
up before I retired and it was great.

394
00:23:13,570 --> 00:23:16,680
You know, we did say Frampton,
we did Kings, Glasgow, and all

395
00:23:16,680 --> 00:23:18,130
of them have got great ideas.

396
00:23:18,970 --> 00:23:21,899
But even if we look at the US,
right, the US has only really

397
00:23:21,900 --> 00:23:23,110
got two or three clusters.

398
00:23:23,450 --> 00:23:27,290
That's a fact and they're unbelievably
good at it and unbelievably big.

399
00:23:27,740 --> 00:23:31,050
But even they can't support, you know,
there's only two really famous ones and

400
00:23:31,050 --> 00:23:35,569
that's the valley in the MIT cluster
and actually, I remember going to, I

401
00:23:35,570 --> 00:23:39,740
think it was Gordon Brown, Tony Blair,
so I'm going back a while, right?

402
00:23:39,820 --> 00:23:44,499
And they were like, we saw your work with
this IP group idea, you know, could we do

403
00:23:44,500 --> 00:23:46,380
it with every single university in the UK?

404
00:23:46,540 --> 00:23:48,520
And I'm like, well, to be honest, no.

405
00:23:49,160 --> 00:23:51,769
And actually, I've probably
done it with too many.

406
00:23:51,840 --> 00:23:58,010
I should have probably stuck to
Cambridge, London Cluster and Oxford.

407
00:23:58,875 --> 00:24:01,215
And of course, it was like, well,
that's not going to play well.

408
00:24:01,225 --> 00:24:02,645
We, you know, what about Manchester?

409
00:24:02,645 --> 00:24:04,225
I said, yeah, I love Manchester.

410
00:24:04,225 --> 00:24:05,565
I'm from Manchester, for God's sake.

411
00:24:05,565 --> 00:24:12,115
And, you know, but you won't
necessarily get the scale and it's

412
00:24:12,145 --> 00:24:14,694
not just about, you've got really good
science, you know, a world leading

413
00:24:14,694 --> 00:24:19,254
university, but if you don't get an
ecosystem around it, it's difficult.

414
00:24:19,534 --> 00:24:19,935
Yeah.

415
00:24:19,985 --> 00:24:23,105
So, you know, let's say the
UK only produced clusters in

416
00:24:23,105 --> 00:24:25,355
London, Oxford and Cambridge.

417
00:24:25,355 --> 00:24:29,535
That'd still be an amazing achievement
that would transform the country.

418
00:24:30,315 --> 00:24:33,114
But obviously they didn't want that,
they were like that's political suicide

419
00:24:33,114 --> 00:24:35,075
for us to be, you know, elitist.

420
00:24:35,244 --> 00:24:36,155
This is elitist.

421
00:24:36,225 --> 00:24:39,325
It's about creating the most powerful
companies in the world with the best

422
00:24:39,335 --> 00:24:42,005
science in the world, run by the
best people in the world, you know.

423
00:24:42,255 --> 00:24:45,635
So there's no, you know, it
doesn't necessarily fit the

424
00:24:45,635 --> 00:24:47,025
sort of levelling up idea.

425
00:24:47,215 --> 00:24:47,655
Yeah.

426
00:24:48,160 --> 00:24:48,900
That's my worry.

427
00:24:48,900 --> 00:24:49,800
I'm brutally honest.

428
00:24:49,800 --> 00:24:50,190
Right?

429
00:24:51,145 --> 00:24:52,925
Well, they've been conflated
almost, haven't they?

430
00:24:52,925 --> 00:24:54,875
And they don't necessarily sit
that comfortably in reality.

431
00:24:54,875 --> 00:24:55,620
I think that's right.

432
00:24:55,895 --> 00:24:59,344
And one can see why, because you have
universities geographically spread

433
00:24:59,344 --> 00:25:00,815
out, you have these great ideas.

434
00:25:00,975 --> 00:25:04,914
It's a tempting thing to say therefore,
hey, let's pump more money in and create

435
00:25:04,924 --> 00:25:09,690
jobs and to some degree, it can be done,
perhaps, but I had somebody called Mark

436
00:25:09,730 --> 00:25:13,449
Preston and he is from the motorsports
industry and we were talking about

437
00:25:13,490 --> 00:25:17,129
the motorsports cluster and one of the
things that he really highlighted, which

438
00:25:17,129 --> 00:25:20,620
is pretty well understood, but it's
very relevant to this conversation, is

439
00:25:20,620 --> 00:25:23,759
just the high labor mobility and that
if you move to Oxfordshire with your

440
00:25:23,759 --> 00:25:27,580
family from anywhere in the world, as
a brilliant motorsports, you know, F1,

441
00:25:27,730 --> 00:25:32,449
Formula E, either an entrepreneur or
somebody, joining one of the big teams,

442
00:25:32,670 --> 00:25:37,570
if that doesn't work out, there are lots
of other jobs here and that's the human

443
00:25:37,790 --> 00:25:42,359
talent reality is that you don't want to
move your family around willy nilly, but

444
00:25:42,360 --> 00:25:44,780
moving them here for motorsports is easy.

445
00:25:45,050 --> 00:25:47,599
So then you need to work out, right,
well, what's adjacent to that?

446
00:25:47,599 --> 00:25:51,740
What can we do that has that kind of
translational experience where people

447
00:25:51,770 --> 00:25:55,220
can say, well, this actually isn't
too far away, so I feel comfortable

448
00:25:55,220 --> 00:25:56,659
taking that job in Oxford too.

449
00:25:56,705 --> 00:25:57,445
Spot on.

450
00:25:57,675 --> 00:25:59,275
And I've actually seen that happen.

451
00:25:59,545 --> 00:26:02,755
Like, even people who came with their
families, like you say, they came from

452
00:26:02,755 --> 00:26:06,774
the US with their families, went into one
job, it didn't work out, or the science

453
00:26:06,774 --> 00:26:11,224
didn't work, or the chemistry didn't
work, and then within a few months they

454
00:26:11,224 --> 00:26:13,215
were over the road at another start up.

455
00:26:13,805 --> 00:26:17,355
And, you know, I used to just
go to Boston and hang out there

456
00:26:17,405 --> 00:26:18,595
for a few days and watch them.

457
00:26:18,595 --> 00:26:22,935
I'd go to the bars, I'd meet some of the
entrepreneurs and just listen to them.

458
00:26:22,965 --> 00:26:23,785
I just listened.

459
00:26:24,314 --> 00:26:25,844
Because I'm like you know what?

460
00:26:26,235 --> 00:26:27,514
I'm not clever, they're clever.

461
00:26:27,534 --> 00:26:31,585
What do you, know, and one of the best
things that someone said to me It's like,

462
00:26:32,114 --> 00:26:36,745
you know, you really need sort of three
things to make an ecosystem work, three

463
00:26:36,745 --> 00:26:40,354
things and I'm like, oh interesting,
I'm gonna listen and he said the first

464
00:26:40,354 --> 00:26:41,614
you need to have world class science.

465
00:26:41,665 --> 00:26:42,054
Tick.

466
00:26:42,105 --> 00:26:42,424
Done.

467
00:26:42,884 --> 00:26:46,365
Secondly, it's got to be just a beautiful
place, a nice place to live and I'm like,

468
00:26:46,725 --> 00:26:48,185
well, that's good, oxford's got that.

469
00:26:48,965 --> 00:26:51,665
The third, you've got to be able
to walk everywhere and it's like,

470
00:26:51,685 --> 00:26:55,465
Ooh, I like that too and that's
how MIT sort of built that cluster.

471
00:26:55,465 --> 00:26:59,765
You see them, they, you know, a scientist
is there, you can walk over for coffee

472
00:26:59,765 --> 00:27:02,635
with another engineer to give him a
job interview, then you can walk over

473
00:27:02,635 --> 00:27:08,645
and see a VC about raising $20 million
to do whatever he wants to do and that

474
00:27:09,345 --> 00:27:11,284
is the beauty of these ecosystems.

475
00:27:11,304 --> 00:27:14,415
You've got to sort of create, and
once it starts to work, it becomes

476
00:27:14,415 --> 00:27:16,645
self referencing and self fulfilling.

477
00:27:17,034 --> 00:27:21,835
But again, realistically, like,
you know can we create an ecosystem

478
00:27:21,835 --> 00:27:23,165
in all these university towns?

479
00:27:23,165 --> 00:27:24,655
Of course we can't, it's nonsense.

480
00:27:24,764 --> 00:27:25,315
We know we can't.

481
00:27:25,820 --> 00:27:29,310
So coming back to kind of that point
around how you build a cluster and

482
00:27:29,400 --> 00:27:33,949
kind of cross pollination between
industry and universities, I'd love

483
00:27:33,949 --> 00:27:37,190
to get your thoughts on the Ellison
Institute for Technology and how that's

484
00:27:37,190 --> 00:27:38,389
going to change the landscape here.

485
00:27:38,565 --> 00:27:39,275
Fantastic.

486
00:27:39,504 --> 00:27:40,435
Just so exciting.

487
00:27:40,485 --> 00:27:41,125
It is isn't it?

488
00:27:41,145 --> 00:27:47,995
Just so exciting and I think just
having someone coming into the ecosystem

489
00:27:48,004 --> 00:27:53,594
like that and doing things a bit
differently and shaking it up and it's

490
00:27:53,594 --> 00:27:58,554
just amazing like, and I'm sort of
so excited because, you know, here's

491
00:27:58,564 --> 00:28:02,674
someone who's built, who's created
success on a scale that we can never

492
00:28:02,674 --> 00:28:05,104
imagine and it's fantastic to have that.

493
00:28:05,104 --> 00:28:10,225
So I think that will, you know and it
hopefully will encourage more people

494
00:28:10,225 --> 00:28:14,495
who've won so big to think about doing
stuff here, like people love Oxford.

495
00:28:14,495 --> 00:28:15,515
Oxford's got this weird...

496
00:28:16,065 --> 00:28:20,435
and if we could pull in some of that
super talent, people who've got so

497
00:28:20,435 --> 00:28:24,425
much more money that they don't need
to worry about money or whatever, but

498
00:28:24,734 --> 00:28:26,635
actually just want to see ideas work.

499
00:28:27,395 --> 00:28:28,565
So I think we need to be bold.

500
00:28:28,594 --> 00:28:33,560
I mean like, areas like DNA
sequencing, I've spent most of my

501
00:28:33,560 --> 00:28:36,770
life on that and AI again, I've
spent most of my life observing that.

502
00:28:37,170 --> 00:28:42,600
You know, the UK could really make a pitch
to be world leading in one of probably

503
00:28:42,600 --> 00:28:44,070
the three big areas in the world today.

504
00:28:44,110 --> 00:28:47,380
I still think the sequencing
of DNA is just everything.

505
00:28:48,190 --> 00:28:51,760
AI is clearly going to change
everything we do and quantum will

506
00:28:51,990 --> 00:28:53,420
speed all of that up as well.

507
00:28:53,420 --> 00:28:57,800
So you've got three areas that are
converging and you know Oxford could be

508
00:28:57,800 --> 00:29:03,560
a world leader in all three and people
could start, like you say, with the

509
00:29:03,589 --> 00:29:06,770
Ellison Institute, you could start to
see that sort of stuff, Oh well, we want

510
00:29:06,770 --> 00:29:10,199
to be part of this and not just part
of it, we will bloody make it happen

511
00:29:10,529 --> 00:29:12,139
because we know how to make it happen.

512
00:29:12,139 --> 00:29:16,260
So giving some of these companies a
bit of a rocket up their backsides,

513
00:29:16,280 --> 00:29:17,360
because some of them do need it.

514
00:29:17,409 --> 00:29:19,889
I mean, some of them are
British as well, right?

515
00:29:19,889 --> 00:29:22,360
We can't just keep blaming
politicians, that's boring, right?

516
00:29:22,900 --> 00:29:24,909
You know, everyone just moans
or give them more money.

517
00:29:25,449 --> 00:29:29,409
But, you know, I do think sometimes
we're complacent, we don't try and

518
00:29:29,409 --> 00:29:30,999
grow our companies as aggressively.

519
00:29:32,150 --> 00:29:34,790
That's definitely something I've
heard before, just that ambition

520
00:29:34,790 --> 00:29:37,920
gap and it's a cliche, but it
seems to be one for a reason.

521
00:29:37,970 --> 00:29:40,770
I mean, again, I mean, I don't want
to get into the politics of it all,

522
00:29:40,770 --> 00:29:44,840
but it's almost slightly traumatizing
that, you know, Moderna delivered a

523
00:29:44,840 --> 00:29:49,020
vaccine and became worth, you know,
20 billion and we delivered a vaccine

524
00:29:49,020 --> 00:29:51,640
and we didn't do anything out of it.

525
00:29:51,640 --> 00:29:55,450
It's a slightly, of course, it was great
because we hopefully saved millions of

526
00:29:55,450 --> 00:30:00,580
lives and then helped particularly in the
developing world because it was cheaper

527
00:30:00,589 --> 00:30:05,080
and more easy to deliver., So it was great
for humanity, but a bit of what we'd also

528
00:30:05,090 --> 00:30:09,975
like to see a sort of, you know, a big
unicorn win out of it, which is what...

529
00:30:10,170 --> 00:30:13,130
And reinvestment back into
the university that housed it.

530
00:30:13,140 --> 00:30:17,195
Exactly, exactly, you know, that's it,
you know, you start to see if this stuff

531
00:30:17,195 --> 00:30:22,084
works, it just goes back into funding
research and inspires that new generation

532
00:30:22,085 --> 00:30:28,895
of scientists who can see, Oh, this lab
was built by this success and that's what

533
00:30:28,895 --> 00:30:32,335
I've spent my life trying to encourage
people to do and at times you do feel

534
00:30:32,335 --> 00:30:34,495
though that we're still sluggish, right?

535
00:30:36,280 --> 00:30:40,310
So coming back to kind of Oxford and
the ecosystem here which you referred

536
00:30:40,310 --> 00:30:43,689
to, you were talking about kind of
going across the road and meeting VCs

537
00:30:43,690 --> 00:30:48,129
and obviously, OSE is a big source
of investment funding for lots of

538
00:30:48,129 --> 00:30:51,809
companies and you also spoke earlier
about being cross department focused.

539
00:30:52,625 --> 00:30:56,395
Now that we are where we are and it's
all still evolving and you know, we've

540
00:30:56,395 --> 00:31:00,914
got this amazing source of capital,
do you still think that being cross

541
00:31:00,915 --> 00:31:06,465
department and dare I say it, trying
to do everything, which has a negative

542
00:31:06,465 --> 00:31:10,785
inferrence I appreciate, is the best
strategy or do you think that we need

543
00:31:10,785 --> 00:31:14,795
to see more emergent kind of singularly
focused funds coming into Oxford?

544
00:31:15,015 --> 00:31:16,024
Yeah, good question.

545
00:31:16,235 --> 00:31:20,075
I think we need to almost go back
to sort of some philosophy, right?

546
00:31:20,135 --> 00:31:22,645
I mean, that sounds a
bit strange, but like...

547
00:31:22,945 --> 00:31:23,505
I'll go with it.

548
00:31:23,515 --> 00:31:25,254
Yeah, let me just give
you a little anecdote.

549
00:31:25,305 --> 00:31:28,665
So, in the early stages of COVID, one of
my favourite pubs, probably my favourite

550
00:31:28,694 --> 00:31:31,915
pub in the world, the first pub I ever
had a pint in Oxford when I arrived

551
00:31:31,915 --> 00:31:36,870
in 1988, was the Lamb and Flag and one
of my old, friends, she sent me this

552
00:31:36,870 --> 00:31:40,690
article in the BBC saying that the Lamb
and Flag had closed because of COVID and

553
00:31:40,690 --> 00:31:44,690
I thought, my God, this is like the end
of an era, like, so many great evenings

554
00:31:44,690 --> 00:31:48,850
there, where we had so much fun, but also
so many serious evenings there, like, you

555
00:31:48,860 --> 00:31:51,959
know, Nanopore you know, we had no money
in the early days, we used to have our

556
00:31:51,959 --> 00:31:56,825
board meetings in the pub, you know, in
the early days of Nanopore and I just,

557
00:31:56,825 --> 00:32:00,825
this is just such a tragedy, we lose
his pub, we lose so much of our history.

558
00:32:00,825 --> 00:32:03,145
Obviously he's got all
the Tolkien and the C.S.

559
00:32:03,165 --> 00:32:06,955
Lewis connection, which is unbelievably
important, you know and I just remember

560
00:32:06,955 --> 00:32:10,695
thinking, I've got to do something
about this, and what I started doing,

561
00:32:10,695 --> 00:32:13,995
I thought, why don't we set it up,
not for profit, something that's

562
00:32:13,995 --> 00:32:18,325
really about the community and about
helping Oxford and bless them, St.

563
00:32:18,325 --> 00:32:20,834
John's, I gave them the pitch and I
think they thought I was completely

564
00:32:20,834 --> 00:32:26,774
crazy and I said, I really want you to
reopen this pub, but allow us to do it

565
00:32:26,785 --> 00:32:28,875
differently and we'll set it up as...

566
00:32:29,090 --> 00:32:32,510
we'll call it The Inklings, named after
The Inklings, and we'll try and pull

567
00:32:32,520 --> 00:32:36,410
together some of the best scientists,
the best writers, the best entrepreneurs,

568
00:32:36,410 --> 00:32:40,600
the best financers, we'll pull everyone
in and anyway, long story short, we

569
00:32:40,600 --> 00:32:43,559
signed up more than 300 Inklings, and St.

570
00:32:43,560 --> 00:32:48,320
John's allowed us to take over, and
we reopened the pub and some of those

571
00:32:48,330 --> 00:32:53,040
300 names, some of them are famous
authors, but a lot of them are world

572
00:32:53,040 --> 00:32:56,440
leading scientists, particularly from
the chemistry department and a lot of

573
00:32:56,440 --> 00:33:00,500
them are world leading entrepreneurs
who built big businesses and no one

574
00:33:00,500 --> 00:33:04,379
was allowed to put in more than £10,000
and the minimum was only £1000, so it

575
00:33:04,379 --> 00:33:05,879
was very democratic, no one could...

576
00:33:06,389 --> 00:33:10,260
But what almost broke my heart was some
of the messages from people who were

577
00:33:10,260 --> 00:33:15,010
like no, I learned my first chemistry
in there, I learned everything in that

578
00:33:15,130 --> 00:33:18,630
pub, I learned more in there than in
the labs and one guy built a business.

579
00:33:19,140 --> 00:33:22,569
I'm not going to embarrass him by saying
who it is, the business was valued at

580
00:33:23,370 --> 00:33:27,940
four billion at the time and he said, I
will, of course, I want to be involved,

581
00:33:27,940 --> 00:33:33,030
I'm honored to be involved because it
was such a big part of my research life,

582
00:33:33,080 --> 00:33:37,400
that pub and he's gone on to build this
amazing company and I just thought, you

583
00:33:37,400 --> 00:33:41,900
know what, doing this sort of process,
I suddenly thought there's so much

584
00:33:41,920 --> 00:33:45,829
going on, there's so many people with
ideas and history and actually I just

585
00:33:45,830 --> 00:33:48,589
thought, you know what, if all we do
is open this pub and some of them meet

586
00:33:48,590 --> 00:33:52,929
each other, we'll have actually done a
massive service to the ecosystem, so...

587
00:33:53,150 --> 00:33:56,570
Well you joke, I've had people
say on this podcast like, where

588
00:33:56,570 --> 00:33:58,070
do you go to meet entrepreneurs?

589
00:33:58,070 --> 00:34:01,370
You know, you bump into them on the
street in the coffee shops in you know,

590
00:34:01,490 --> 00:34:05,060
Silicon Valley or you know, as you were
saying in Boston and people have literally

591
00:34:05,060 --> 00:34:06,650
said, oh, you go to the Lamb and Flag.

592
00:34:07,095 --> 00:34:09,205
And it is, you know, it's incredible.

593
00:34:09,205 --> 00:34:10,195
I reckon I'm going to...

594
00:34:10,195 --> 00:34:12,255
We are not sponsored by the
Lamb and Flag by the way!

595
00:34:13,395 --> 00:34:16,795
But I'll go there tonight and
I'm certain I will bump into

596
00:34:17,045 --> 00:34:18,934
entrepreneurs, CEOs, whatever.

597
00:34:19,215 --> 00:34:21,144
So what is my dream?

598
00:34:21,144 --> 00:34:23,935
What I want to see, because I'm
thinking, oh, I'm 55, right?

599
00:34:24,145 --> 00:34:28,970
I would want to see some young person
in the Lamb and Flag, a scientist

600
00:34:28,970 --> 00:34:33,270
who's got an idea that's going to
change the world and meeting someone

601
00:34:33,270 --> 00:34:34,610
who says, right, you know what?

602
00:34:34,760 --> 00:34:38,779
I sold my business 5, 10 years ago,
I've got half a billion dollars in

603
00:34:38,780 --> 00:34:42,250
the bank and I'm going to back you and
we're going to work together, I'll go

604
00:34:42,250 --> 00:34:46,680
chair, you go CEO and we won't sell
out quickly to whoever comes along, you

605
00:34:46,680 --> 00:34:51,080
know, just, and I'll help you avoid the
mistakes that I made and that's like...

606
00:34:51,125 --> 00:34:52,105
So sort of peer to peer.

607
00:34:52,340 --> 00:34:56,575
Exactly and you know, and it clearly
won't work like that if it sounds twee

608
00:34:56,595 --> 00:35:00,135
but you know, just seeing things like that
Ellison Institute, you realise that that

609
00:35:00,135 --> 00:35:06,355
magic rubs off, it becomes part of the DNA
of Oxford and part of the Oxford story,

610
00:35:06,355 --> 00:35:09,875
which for me is still incredibly romantic,
there's been so many disappointments,

611
00:35:09,925 --> 00:35:13,565
it's taken too long, and I'm still a
believer that some of the best ideas

612
00:35:13,565 --> 00:35:16,970
in the world are in Oxford, and at some
point they will see the light of day,

613
00:35:17,070 --> 00:35:20,010
you know, First Light Fusion is a dream.

614
00:35:20,020 --> 00:35:24,000
If it works, it will be one of the most
important companies ever, right, in the

615
00:35:24,000 --> 00:35:28,285
history of the world, you know, we'll see
if it works, I desperately pray it does,

616
00:35:28,335 --> 00:35:31,555
but that's what you're playing for and if
you have enough shots on goal like that.

617
00:35:32,355 --> 00:35:36,185
So rather than these kind of slightly,
let's build it, finance it, sell it

618
00:35:36,195 --> 00:35:39,434
for a hundred two hundred, million
or whatever, I would love to see

619
00:35:39,434 --> 00:35:43,365
some dreaming again, you know, like
some, Oxford is about dreaming.

620
00:35:43,365 --> 00:35:46,234
That's the whole point, particularly
if you're younger, but if you can have

621
00:35:46,234 --> 00:35:50,854
young people who are brilliant with
dreams, marrying up with older people

622
00:35:50,854 --> 00:35:56,000
with money and experience, we could
do some serious damage and I worry

623
00:35:56,000 --> 00:35:58,120
that we've not, we mustn't lose that.

624
00:35:58,320 --> 00:36:00,560
We've got to keep that magic.

625
00:36:00,560 --> 00:36:01,230
That connectivity.

626
00:36:01,250 --> 00:36:04,740
Exactly and like I say, people in
the world, what do people want to do?

627
00:36:04,760 --> 00:36:05,589
They want to have impact.

628
00:36:05,700 --> 00:36:10,499
So actually, even though funding is
difficult, everything's difficult,

629
00:36:10,740 --> 00:36:13,549
if you've got a really good idea
that will have positive impact on

630
00:36:13,550 --> 00:36:16,940
the world, the chances are someone
out there will help you get there.

631
00:36:17,225 --> 00:36:21,510
And do you think that, you know,
ironically, the kind of deal that's

632
00:36:21,510 --> 00:36:28,029
in place with OSE that has this agreed
IP for the ideas that come out, do

633
00:36:28,030 --> 00:36:31,099
you think that has any dampening
effect on those individuals thinking,

634
00:36:31,100 --> 00:36:32,510
oh well it's already spoken for?

635
00:36:32,860 --> 00:36:36,680
Obviously the intention isn't that, but
I've definitely heard, I've definitely

636
00:36:36,680 --> 00:36:38,930
heard suggest things along that line.

637
00:36:39,180 --> 00:36:39,910
It's a good question.

638
00:36:39,935 --> 00:36:43,265
Probably good to clarify this because
I've probably heard every side of

639
00:36:43,265 --> 00:36:45,125
the argument, again, not forever.

640
00:36:45,125 --> 00:36:48,185
So I know that I'm not anything
to do with anything, I can sort

641
00:36:48,185 --> 00:36:50,015
of talk about it dispassionately.

642
00:36:50,015 --> 00:36:55,955
So I mean, the way all the deals
that were ever done, whether it was

643
00:36:55,955 --> 00:37:00,935
IP group or OSI or CEOs there is,
had a simple philosophy that they

644
00:37:00,935 --> 00:37:02,765
only shared the university stake.

645
00:37:03,745 --> 00:37:06,025
They never took anything off
the scientists themselves,

646
00:37:06,465 --> 00:37:07,635
that was the whole philosophy.

647
00:37:07,685 --> 00:37:12,664
So theoretically, the scientists can never
be any worse off because unfortunately,

648
00:37:12,665 --> 00:37:17,785
when we did this Oxford deal, some kind
of lots of strange things sort of started

649
00:37:17,815 --> 00:37:22,205
to happen where people are like, well, the
UK, the reason the UK because universities

650
00:37:22,215 --> 00:37:26,455
are taking too much equity, which isn't
interesting and obviously the scientists

651
00:37:26,465 --> 00:37:29,095
love that idea because it's like, well,
the university should have no equity or

652
00:37:29,095 --> 00:37:30,277
maybe 5 percent and we'll get it all.

653
00:37:30,277 --> 00:37:34,460
Well I think the spin out review
has done quite a lot to break  out

654
00:37:34,460 --> 00:37:36,890
that myth and the fact that Irene
Tracy was one of the co-authors.

655
00:37:36,915 --> 00:37:37,545
Exactly.

656
00:37:37,605 --> 00:37:39,565
But that was where it all
kind of got conflated.

657
00:37:39,565 --> 00:37:42,765
You know, there's something like,
and I'm like, well, you know, we

658
00:37:42,765 --> 00:37:46,325
get what we get, we just get half
the university stake for which we've

659
00:37:46,545 --> 00:37:48,199
committed a huge amount of capital.

660
00:37:48,199 --> 00:37:53,334
We didn't get given it because you know,
they got this massive stake and Oxford got

661
00:37:53,335 --> 00:37:55,695
600 million for its projects, you know?

662
00:37:55,695 --> 00:38:00,035
So, you know, so to me, I
am still slightly of the...

663
00:38:00,515 --> 00:38:04,525
at the end of the day, the university
is a charity and if you are an employee

664
00:38:04,525 --> 00:38:07,765
of the university and you come up with
a brilliant idea, you should want the

665
00:38:07,765 --> 00:38:12,535
university to have a big stake and
actually, one of the things that I did was

666
00:38:12,555 --> 00:38:18,935
to give my stake in OSI to the university,
to my old college, because I thought,

667
00:38:18,935 --> 00:38:21,865
well I don't want anyone thinking I'm
here to try and make money and exploit

668
00:38:21,895 --> 00:38:23,455
these scientists, so I actually gave it.

669
00:38:23,805 --> 00:38:26,255
So it paid towards the H.

670
00:38:26,255 --> 00:38:26,345
B.

671
00:38:26,365 --> 00:38:27,055
Allen Center.

672
00:38:27,300 --> 00:38:27,480
Okay.

673
00:38:28,260 --> 00:38:28,710
Amazing.

674
00:38:28,985 --> 00:38:32,655
And I actually really believe passionately
that, you've got to want to...

675
00:38:33,615 --> 00:38:37,815
the university, if you're there and
a professor and you've had 20 years

676
00:38:37,825 --> 00:38:39,934
there, why wouldn't you want the
university to do well out of it?

677
00:38:39,934 --> 00:38:43,234
It's going to pay for your
labs, your students, it's...

678
00:38:43,245 --> 00:38:47,260
so, I think the debate got very charged
and very emotional and this, you know,

679
00:38:47,470 --> 00:38:51,630
we could talk about it for hours, but
I think they probably arrived at a

680
00:38:51,700 --> 00:38:56,279
reasonable place, but I don't believe
ever, sorry just to finish, I'll have

681
00:38:56,279 --> 00:39:00,500
my rant here, this idea that, oh well
that's why the UK's doing badly because

682
00:39:00,549 --> 00:39:03,470
the universities gobbled all the
equity, that's just bollocks, I'm sorry.

683
00:39:03,840 --> 00:39:08,830
No and I agree with you and as I say, the
spin out review has been very helpful to

684
00:39:08,830 --> 00:39:13,800
sort of really open up what everyone's
doing and compare it in broad daylight.

685
00:39:13,880 --> 00:39:17,180
You know, kind of have the conversation
in the open, such as we're doing here.

686
00:39:17,990 --> 00:39:21,590
It does, from conversations I'm
having, and I'm not subject to it,

687
00:39:21,660 --> 00:39:25,740
but I don't think that people don't
want the university to have it.

688
00:39:25,755 --> 00:39:30,725
I think that there has been a sense that
somehow the signaling power of having the

689
00:39:30,725 --> 00:39:36,295
university is not somehow a positive thing
and I guess I would say that out loud,

690
00:39:36,295 --> 00:39:39,245
not because I necessarily agree with it,
you know, part of the tagline of Oxford

691
00:39:39,245 --> 00:39:43,185
Plus is to kind of dispel some of the
myths and I would say this is a pretty

692
00:39:43,185 --> 00:39:49,855
well propagated myth and I think that
it's quite important that we are sort of

693
00:39:49,875 --> 00:39:53,735
actively reaching out to people such as
you've suggested, but also kind of, you

694
00:39:53,735 --> 00:39:59,874
know, institutions, entities, and make
sure that Oxford has the right reputation

695
00:40:00,275 --> 00:40:05,254
as an investor, increasing the probability
of success and I don't, truthfully,

696
00:40:05,295 --> 00:40:07,525
really understand why that isn't the case.

697
00:40:07,850 --> 00:40:08,760
It's an interesting one.

698
00:40:08,760 --> 00:40:11,910
So I can only speak from my experience.

699
00:40:12,250 --> 00:40:21,039
2015, I kind of came back and I retired
when I turned 50, which was January 2019.

700
00:40:21,130 --> 00:40:22,479
So I sort of had four years.

701
00:40:23,439 --> 00:40:26,380
I think in that four years, you'd
have to check the numbers, but I think

702
00:40:26,390 --> 00:40:30,040
I'm probably confident that in that
four years we created more spin outs

703
00:40:30,280 --> 00:40:34,020
and raised more capital than in the
last 20 years, just in four years.

704
00:40:34,155 --> 00:40:35,465
Which is an extraordinary achievement.

705
00:40:35,465 --> 00:40:38,185
So to me everyone, like, Oxford,

706
00:40:38,395 --> 00:40:42,425
what I love about Oxford, right, you know,
you've got 20,000 incredibly clever people

707
00:40:42,504 --> 00:40:44,654
all disagreeing all the time, right?

708
00:40:44,714 --> 00:40:46,245
So I've just learned to live with that.

709
00:40:46,845 --> 00:40:48,475
But ultimately, numbers
are numbers, right?

710
00:40:48,485 --> 00:40:52,294
Since Oxford Sciences arrived,
the figures, any kind of matrix,

711
00:40:52,294 --> 00:40:54,155
anything you want to look at,
just went through the roof.

712
00:40:54,485 --> 00:40:57,555
You know, and funds came and invested
in Oxford, who'd never invested in

713
00:40:57,725 --> 00:41:00,678
Oxford, never even been to Oxford and
I know that because I've brought a lot

714
00:41:00,678 --> 00:41:03,175
of them here and they said, Oh, we've
never been here, this is beautiful,

715
00:41:03,275 --> 00:41:04,535
maybe we'll hang out here more,

716
00:41:04,655 --> 00:41:04,985
you know?

717
00:41:05,055 --> 00:41:05,355
So...

718
00:41:05,605 --> 00:41:06,755
And are they still coming?

719
00:41:06,755 --> 00:41:12,130
They're still coming, but again, so I'm
not here to do an advert for OSC, right?

720
00:41:12,160 --> 00:41:18,725
That's not, I left in 2019, I think, you
know, it's still run by people who I'm

721
00:41:18,735 --> 00:41:22,105
very good friends with, I've got a drink
with one of the senior people tonight.

722
00:41:22,725 --> 00:41:27,095
I think, you know, it's common knowledge
OSC had some management issues, I left

723
00:41:27,095 --> 00:41:34,715
and then they went through two CEOs and it
all became a bit, you know, COVID hit, so

724
00:41:34,715 --> 00:41:36,805
probably the personal thing wasn't there.

725
00:41:36,845 --> 00:41:40,325
I think some of the scientists
like, oh, we don't see OSC anymore.

726
00:41:40,685 --> 00:41:44,805
I still can't get used to the name change
as well so you know, we don't, whatever

727
00:41:44,805 --> 00:41:45,894
they call it, we don't see them anymore.

728
00:41:45,895 --> 00:41:49,420
So I think there was a bit of, you
know, oh he's having a bit of a dark

729
00:41:49,420 --> 00:41:52,300
patch, not to say that it was under
a great patch with me under it.

730
00:41:52,320 --> 00:41:55,200
I'm not trying to make that pointment,
I think there was definitely some

731
00:41:55,490 --> 00:41:59,940
internal strife, I think and I'm very
hopeful they've got through that, I

732
00:41:59,940 --> 00:42:04,390
hear good things again, I hear oh yeah,
we saw them again last week and it's,

733
00:42:04,900 --> 00:42:06,190
we, are all working together, so...

734
00:42:06,290 --> 00:42:08,570
And actually I've got Ed Bussey
coming on next week and I'm really

735
00:42:08,570 --> 00:42:09,910
excited to hear what the plans are.

736
00:42:10,130 --> 00:42:14,369
I'm very excited that, you know, there's a
platform where, hopefully, further to this

737
00:42:14,370 --> 00:42:19,580
conversation, we'll be able to dispel, in
sort of real time and meet some of those,

738
00:42:19,800 --> 00:42:25,200
not criticisms, that's too strong, but
like, you know, get up in front of it.

739
00:42:25,360 --> 00:42:28,590
I've always said, like I said, that's
why I gave away my shares at the start.

740
00:42:28,900 --> 00:42:33,010
So I was like, all I've ever wanted
is to see brilliant ideas in Oxford

741
00:42:33,499 --> 00:42:34,669
get out there into the world.

742
00:42:34,860 --> 00:42:37,150
So if there's anything stopping
that, I want to know about it.

743
00:42:37,760 --> 00:42:40,469
like, so to me, but you
know, I've not heard any...

744
00:42:40,649 --> 00:42:41,969
Like anything isn't it?

745
00:42:41,969 --> 00:42:45,150
You know, it takes years to win a good
reputation, and it can be a short period

746
00:42:45,440 --> 00:42:48,849
where, you know, you can lose it and we
spoke about this on the way over here to

747
00:42:48,850 --> 00:42:52,609
the studio, but I think it's incredibly
easy to be a naysayer, and actually we

748
00:42:52,609 --> 00:42:57,035
need to be part of people saying right,
we can be more than the sum of our parts.

749
00:42:57,035 --> 00:42:58,395
We've got a lot of good stuff here.

750
00:42:58,675 --> 00:43:01,865
I love this, but pie makers and pie
eaters, like everyone just wants the pie

751
00:43:01,875 --> 00:43:05,395
to be bigger because then everyone does
better rather than worrying about, you

752
00:43:05,395 --> 00:43:10,065
know, everyone's little fiefdoms and I
think it's really important that Oxford

753
00:43:10,124 --> 00:43:14,035
and all of its stakeholders take some
responsibility for being constructive.

754
00:43:14,725 --> 00:43:18,725
100 percent agree and Oxford has
got this weird, like, I love the

755
00:43:18,725 --> 00:43:21,835
place, but it does have an amazing
ability to be petty at times.

756
00:43:22,024 --> 00:43:25,585
Yeah, I've seen it happen at a drinks
party where it's like, you know,

757
00:43:25,595 --> 00:43:27,065
that person's over there, right?

758
00:43:27,295 --> 00:43:29,045
Are you serious that you're saying this?

759
00:43:29,075 --> 00:43:30,225
And I was really shocked.

760
00:43:30,635 --> 00:43:34,665
So, you know, we're all just got to get
stronger and bigger and get on with it.

761
00:43:34,725 --> 00:43:37,900
I don't live here anymore, so I
miss the place and the main reason

762
00:43:37,900 --> 00:43:41,600
I come back is to visit my pub, but
you know, there's nothing I want to

763
00:43:41,600 --> 00:43:45,810
see more in my life than these ideas
work and Oxford reach its potential.

764
00:43:45,810 --> 00:43:47,175
That's so important, right?

765
00:43:47,415 --> 00:43:50,175
You know, again, on the way over, we
were talking about cancer vaccines,

766
00:43:50,445 --> 00:43:53,525
you're talking about blood sugar
testing, you know, these are things

767
00:43:53,535 --> 00:43:56,744
that change millions of lives
and we all want to see it happen.

768
00:43:56,744 --> 00:43:58,870
Absolutely and this place has got it.

769
00:43:58,900 --> 00:44:00,030
You know, what do we know?

770
00:44:00,390 --> 00:44:05,030
The world has got a lot of problems and
we also know that a lot of the solutions

771
00:44:05,130 --> 00:44:06,780
are in this beloved city of ours.

772
00:44:06,790 --> 00:44:10,300
So, you know, we've just got to have that
ambition to say, right, we're going to

773
00:44:10,380 --> 00:44:12,389
go for it and nothing's going to stop us.

774
00:44:12,544 --> 00:44:14,624
So when are we going to host
the big Oxford conference when

775
00:44:14,624 --> 00:44:15,895
we get everybody to come here?

776
00:44:16,340 --> 00:44:16,950
You know what?

777
00:44:17,850 --> 00:44:23,370
Again, maybe it was COVID, but we need
to do more of that, you know, Oxford's

778
00:44:24,170 --> 00:44:28,440
got some of the nicest buildings in the
world, what they should be doing, and OSE

779
00:44:28,820 --> 00:44:34,500
should be helping them and it's like, fill
those buildings, fill them with the best

780
00:44:34,500 --> 00:44:38,480
ideas in Oxford and the best people in the
world, it's not complicated, that's what

781
00:44:38,480 --> 00:44:40,400
needs to get done, and that's what I did.

782
00:44:40,420 --> 00:44:44,889
I wore myself out doing it, you know,
but I kind of, it's like, you know,

783
00:44:44,929 --> 00:44:45,969
we're going to have another conference.

784
00:44:46,689 --> 00:44:48,359
, We don't just want to talk about AI.

785
00:44:48,359 --> 00:44:51,919
We want to show everyone what we've
got, you know, and, if we think

786
00:44:51,929 --> 00:44:54,999
we've got another Nanopore, it's
like, here, this is what we've got,

787
00:44:55,049 --> 00:44:59,659
and we have to be ambitious and give
them nice dinners at High Table.

788
00:44:59,669 --> 00:45:01,779
It doesn't matter if you're one of
the richest people in the world.

789
00:45:01,779 --> 00:45:03,179
It's so fabulous, it's such a treat.

790
00:45:03,329 --> 00:45:06,929
Well, as we've seen with the
Ellison Institute, people who are

791
00:45:07,009 --> 00:45:10,519
successful beyond anything we can
imagine still want to be involved

792
00:45:10,519 --> 00:45:11,969
in these projects and that...

793
00:45:12,089 --> 00:45:13,429
are hallowed halls, right?

794
00:45:13,529 --> 00:45:16,579
It's a privilege to live here, it's a
privilege to go into a college, it's

795
00:45:16,579 --> 00:45:19,659
a privilege to be around people that
their ideas have the potential to

796
00:45:19,659 --> 00:45:22,669
change the world and all the rest of
us need to do is get on board and be

797
00:45:22,669 --> 00:45:24,839
helpful in whatever way we are capable.

798
00:45:25,034 --> 00:45:28,204
It's funny you say that, it takes
me back to, days when I'd just

799
00:45:28,204 --> 00:45:31,304
arrived as an undergraduate and
probably I was a bit cocky in those

800
00:45:31,304 --> 00:45:32,684
days because I was a chess player.

801
00:45:32,684 --> 00:45:34,009
You don't know what you don't know yet!

802
00:45:34,319 --> 00:45:36,834
Yeah, you just think, you
know, and like some people, Oh,

803
00:45:36,834 --> 00:45:37,994
he's like a top chess player.

804
00:45:38,649 --> 00:45:38,869
Yeah.

805
00:45:38,869 --> 00:45:40,319
I mean, you have more reason than most.

806
00:45:40,384 --> 00:45:45,044
Well, no, you know, and I remember
like, I think he was the college stud,

807
00:45:45,044 --> 00:45:48,144
he was a good looking guy, he was
brilliant at sport and all that stuff

808
00:45:48,144 --> 00:45:52,194
and he came up to, I think I wanted  to
join the squash team, he let me play

809
00:45:52,194 --> 00:45:53,794
squash with him to give me a trial.

810
00:45:53,794 --> 00:45:57,554
He said, you might make it into the
third team, you know, so it was like a...

811
00:45:58,084 --> 00:46:02,144
and I just remember him sort of walking by
me and say, yeah, you've got a chess set?

812
00:46:02,144 --> 00:46:04,514
I said, yeah, I don't know.

813
00:46:04,514 --> 00:46:07,534
He said, what you need to understand
about Oxford, he's like a year older

814
00:46:07,534 --> 00:46:10,774
than me, he wasn't my tutor, you know he
said, what you need to understand about

815
00:46:10,774 --> 00:46:13,904
Oxford is no matter how big you think
you are, it's so much bigger than you.

816
00:46:14,924 --> 00:46:18,914
Actually it's not a bad point,
you know, it's not a bad point.

817
00:46:19,024 --> 00:46:21,289
No, I've said that to lots of
people since I've moved here.

818
00:46:21,679 --> 00:46:24,729
Thank you, Dave, this has been
a really great conversation.

819
00:46:24,739 --> 00:46:27,949
Is there anything else you want to
add that you feel we haven't covered?

820
00:46:28,064 --> 00:46:32,644
No, I suppose the only thing that, you
know, lots of new ideas in therapeutics

821
00:46:32,644 --> 00:46:38,874
and vaccines, there's no question, we need
to see the convergence of AI with some

822
00:46:38,874 --> 00:46:44,043
of our, you know, things like chemistry
and drug libraries because that will

823
00:46:44,043 --> 00:46:49,153
change everything, you know, the minute
we start to use the power of generative

824
00:46:49,153 --> 00:46:53,693
AI to do research faster, it will be
transformational, particularly when you

825
00:46:53,693 --> 00:46:56,173
sort of throw quantum computing into that.

826
00:46:56,493 --> 00:47:01,123
So you start to think, well, if there's
ever been a time in human history,

827
00:47:01,203 --> 00:47:04,753
this is the historian in me sort
of struggling to come out, I think

828
00:47:04,753 --> 00:47:08,468
we're going to see the equivalent
of, you know, a hundred industrial

829
00:47:08,468 --> 00:47:09,998
revolutions in the next ten years.

830
00:47:10,898 --> 00:47:15,128
Literally, that's what I believe,
passionately and that could, a big part

831
00:47:15,128 --> 00:47:18,878
of it could happen in Oxford and it
only needs one idea to work in Oxford.

832
00:47:19,368 --> 00:47:21,998
We've seen how big ideas are, like
that's what the Americans have

833
00:47:21,998 --> 00:47:27,148
taught us, you have one idea and it
can be worth a couple of trillion.

834
00:47:27,718 --> 00:47:30,898
So, you know, I'd love to
see people dreaming again.

835
00:47:30,948 --> 00:47:34,648
Like, the biggest ideas in the
world, some of them are here, why

836
00:47:34,668 --> 00:47:39,333
can't we have at least one that
starts to have that ambition.

837
00:47:39,648 --> 00:47:40,638
And just be ambitious.

838
00:47:41,388 --> 00:47:41,858
Thank you.

839
00:47:42,063 --> 00:47:42,433
Brilliant.

840
00:47:42,433 --> 00:47:42,893
Thank you.

841
00:47:43,328 --> 00:47:46,078
Thanks for listening to this
episode of Oxford Plus, presented

842
00:47:46,078 --> 00:47:47,488
by me, Susannah de Jager.

843
00:47:47,968 --> 00:47:50,558
If you want to stay up to date
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844
00:47:50,568 --> 00:47:54,988
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845
00:47:55,078 --> 00:47:56,458
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846
00:47:56,798 --> 00:47:59,988
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847
00:47:59,988 --> 00:48:01,648
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