Welcome to Pulse: Amplify, where we sit down with the leaders and changemakers shaping the future of health.
In this episode Louise and George sit down with Dr Mehmood Khan, CEO of Hevolution Foundation, and Her Royal Highness Princess Dr Haya Bint Khaled Bin Bandar Al Saud, Senior Vice President of Research at Hevolution. Based in Riyadh and backed by Saudi Arabia's Vision 2030, Hevolution is the world's largest philanthropic funder of healthspan science, with over USD $400 million allocated in just three years.
Timed with the release of the second edition of Hevolution's
Global Healthspan Report - the most comprehensive look at the field across 23 countries - this conversation moves beyond the longevity hype to explore what it takes to extend healthy human life
for the benefit of all.
In this episode:
- Healthspan, not longevity - Why Hevolution is focused on keeping people physically, mentally, and financially independent, and why a global non-profit is the right vehicle for a challenge governments and private enterprise can't tackle alone.
- Why Saudi Arabia, why now - Princess Dr Haya on the demographic shift driving the kingdom's leadership, and why a young population on the brink of ageing is uniquely placed to redesign systems before they break.
- The science that has scientists excited - GLP-1 agonists, senotherapeutics, CRISPR, and cellular reprogramming, and why the real breakthrough is the convergence of these fields, not any one of them in isolation.
- A jaw-dropping case study - Dr Khan walks through how rejuvenating aged liver cells eliminated chronic Hepatitis B in animal models, with first-in-human trials now underway. A profound example of aging biology rewriting the rules for treating incurable diseases.
- What clinicians need to know - Two-thirds of healthcare professionals are now getting monthly healthspan questions from patients. Princess Dr Haya on the shift from reactive to proactive care, and the urgent need for evidence-based healthspan protocols.
- A message for policymakers - Why the Minister of Finance, not just the Minister of Health, needs to be at the table, and why retirement, education, and workforce policies built for a 1%-over-65 world are catastrophically out of date.
- Where digital health innovators should be looking - The five years that could be cut from drug development with better data tools, the four proven interventions that lend themselves to digital monitoring, and why we already have the technology - just not the policy frameworks to deploy it.
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