Dr. John Christodouleas on highlights from ASTRO 2025, the promise of adaptive radiotherapy and the ongoing proton debate

In this episode, Dr. John Christodouleas, Elekta’s Senior Vice President of Medical Affairs and Clinical Research, gives his take on scientific highlights from the 2025 American Society for Radiation Oncology (ASTRO) Annual Meeting, including promising evidence for MR-guided radiation therapy for prostate patients and the growing potential of low-dose radiation therapy for non-malignant conditions. He also addresses the ongoing debate around proton therapy and explains why he believes the future of radiation therapy is adaptive.

 

Tune in to hear why John thinks he has the best job in the world and who the newest member of the Medical Affairs team is.

Creators and Guests

Host

Emily Basset

A former therapy radiographer and dosimetrist with extensive clinical experience in radiotherapy, Emily is the Director of Global Clinical Communications for Elekta, where she leverages her technical and clinical expertise.

Guest

Dr. John Christodouleas

Dr. Christodouleas is SVP of Medical Affairs and Clinical Research at Elekta and an internationally-recognized radiation oncologist, specializing in prostate and bladder cancer. He is a national authority on image-guided proton therapy and intensity modulated radiotherapy, with numerous publications, and more than 20 book chapters to his name. John has led research initiatives at the University of Pennsylvania, reviewed for major oncology journals, and co-edited a leading radiation oncology textbook. Currently, he is advancing MR-guided radiation therapy as co-primary investigator of the global MOMENTUM Study, an international effort to optimize MR-Linac treatments for patients worldwide.

What is Spilling the RT?

Spilling the RT is a podcast series from Elekta that features conversations around radiation therapy with clinical experts who are changing the game in radiation oncology. Each episode explores exciting research, technology or emerging trends with leaders who are not just advancing the field, but passionate about making a difference. Plus, we get personal – discovering what drives these individuals and how their journeys began.

Hosted and moderated by Elekta’s Global Clinical Communications Manager, Emily Basset, this series is your front-row seat to everything radiotherapy. Subscribe to Spilling the RT on Apple and Spotify or listen on Elekta’s YouTube channel.