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Yaiza Gomez-Mejias: Hello and
welcome to the February episode

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of Chattering With iCatCare.

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I'm Yaiza Gomez Mejias, Veterinary
Community Coordinator and

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host of this month's podcast.

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Our clinical spotlight this month is
focused on the new consensus guidelines

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on the diagnosis and management of
lower urinary tract disease in cats.

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I will be speaking with two authors,
Sam Taylor and Rachel Korman, about

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the new perspectives discussed
in these practice guidelines.

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But first, Sarah Ellis will be
interviewing Noema Gajdos about the

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iCatCare award she received this year
at the European Veterinary Congress of

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Behavioural Medicine and Animal Welfare.

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Sarah Ellis: So the International
Cat Care Welfare Research

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Award,  we conceived it last year.

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And it's designed to recognise
and celebrate individuals who have

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a dedicated piece of research to
improving domestic cat welfare.

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And of course, when we consider

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welfare at iCatCare, we're thinking
about both the physical health and the

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mental wellbeing of the animal and the
interplay between those two things.

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Now, the research that we were willing
to award could come from any discipline

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within animal welfare, including
Behavioural medicine, ethics, and law.

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And the award aimed to encourage
researchers from a variety of

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disciplines to conduct cat welfare
research and to disseminate such

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research in ways that make meaningful,
positive differences to cat welfare.

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And we used a team of experts
to judge the abstracts blindly.

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And they were from International Cat
Care staff, from our Feline Wellbeing

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panel, which we have as a group of
experts, and even one of  our trustees.

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And we judged those abstracts
and it was unanimous that your

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abstract came out as a winner.

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And the title of that was Screening
for Association Between Mental and

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Physical Health Condition of Feline
Patients During Veterinary Consultation

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Using the Home Feline Stress Score.

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Again, huge congratulations, but I'd be
really interested to hear what inspired

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you to do that piece of research.

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Noema Gajdos Kmeco: The first spark
was the work presented at ISFM Congress

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in 2022, in Rhodes, it was the poster,
presented by Magdalena Glebocka,

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and it was a three stage Delphi study
with caregivers, but also feline

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behaviour or feline medicine expert,
and the result of this Delphi study

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was the home feline stress score.

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So you have 10 items you answer yes or
no, which was designed to be used by

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caregivers in its five item version,
but also, by vets in 10 item version.

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And this abstract was awarded
by the two committees present.

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And I was really excited about
the work myself  and having

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their like poster myself.

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I had this chance to speak actually
with Magdalena about this work and

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the potential uses, and they really
designed it to be used by the vets

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in general veterinary practice.

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And shortly after that, I had a very
enthusiastic student at that time.

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She was the UK nurse studying
for the doctor of veterinary

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medicine degree at our university.

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And she wanted to do the study, which
would be like focused on cats because she

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was studying towards specialisation in a
feline medicine and emergency medicine.

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So she was really like
hands on practical person.

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And she came to me, if I had some like
topics, which she could look into.

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So I had this idea that it would be nice
to test this 10 item home feline stress

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score in a general veterinary practice
and first opinion practice environment.

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And actually to use it to see if there
is a difference in a stress score

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between the healthy cat population
and sick cat population, which are

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coming to the first opinion practice.

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So she liked the idea and we started
this small  study with the aim to

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find out something which actually
she herself could be able to use

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once she finishes her veterinary
degree in practice, but also myself.

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Sarah Ellis: That's great.

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And, one of the things that we loved
about your research is that clinical

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application that actually, you say maybe
it's a small or a straightforward study,

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but actually some of those studies can
have really big, real world application,

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and that's what's really important,
and big things come from small seeds.

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As judges, we did not know at all at
the time, and found out subsequently

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from yourself, was that your
research was inspired by another

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researcher, which, as you said,
you met at one of our congresses.

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And that really highlighted to me the
importance of everybody being brave

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enough to get their research out there,
regardless of how big or how small they

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think their research is, whether it's
a student project or a large grant,

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to be brave and get it out there and
to chat to each other, because that's

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where those sparks happen, isn't it?

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And lo and behold, there's this
whole network now that's come and

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I'm sure you will stay in touch and
it's fantastic that you've used the

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score that she developed further.

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So can you tell us a little bit more about
the results that you got from that study?

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Noema Gajdos Kmeco: Yeah.

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So we just did the one page survey,
a few questions about the cat owner,

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a few questions about the cat.

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So age, breed, sex, if
the cat is neutered.

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And then we asked these 10 questions so,

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Sarah Ellis: Hi, Sorry to
interrupt you Noema, were they

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asked as a paper questionnaire?

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Noema Gajdos Kmeco: Yeah.

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Yeah.

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The whole idea was to make
it as real life as possible.

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So as part of the interview, during
the examination or in the waiting

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room, Natalie and I interviewed
UK caregivers and also Slovak

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caregivers, approximately half to
half, with this paper based interview,

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asking these few simple questions.

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It was aimed to be very quick, so
very concise, up to five minutes.

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We learned about these 10
possible stress indicators.

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Within the HFSS, we asked if the cat is
spending more time sitting or hiding in

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unusual places, whether it is increasingly
seeking attention, whether it's being

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scared more easily, if the neuter cat is
doing the urines spraying, if the cat is

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urinating indoors, and then there are five
extra questions, which we were entitled

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to ask as the veterinary professionals.

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If the cat has been treated for societies,
if it's hissing more at other people

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or cats, if it's attacking other cats
or people more than before, if it's

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grooming to the point of the hair loss
and if it's being blocked or prevented by

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other cats from access to key resources,
more now in comparison with some past.

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So we asked these questions and we
analysed data on 50 cats, so 27 of them

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were healthy, 23 were unhealthy, so almost
equal number of cats in these groups.

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For the statistics enthusiasts, we used
rock curve and regression models, so

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the rock curve, or this, the key finding
was that we found this association

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between this physical health, and
which we call it as real binary thing.

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So came out as healthy from the basic
physical examination or not healthy.

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So usually this where cats come in
with a problem,  healthy cats were

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coming for checkups and vaccinations.

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And we found this association
between this physical health, this

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binary state, and the mental health
represented by this stress score.

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However, this association
was quite weak, so it was the

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significance, the p value was 0.49.

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So it was really on the
borderline with randomness.

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But there was an association and
so it really seemed that the sick

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cats tended to have higher stress
score and we could suspect that cats

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scoring high on HFSS to be sick.

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So hence there is another confirmation
how the health does not only have the

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physical aspect, but also mental as well.

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But there were also cats which scored
relatively high on the stress score, but

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came out from the clinical examination
clinically healthy and vice versa.

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So what this result can tell us is
that no such tool we develop is about

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proof and probably, that wasn't really
the point of developing this tool.

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But and it also tells us that we
shouldn't be, if you're a vet,

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relying on caregiver's  report is
not, it's not a hundred percent thing.

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And the caregiver's report is,
might also not be a hundred percent

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accurate, but often, because
of very understandable reasons.

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And on the other hand, we also as
vets need to be honest with ourselves.

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The basic clinical examination may
not reveal some of the physical

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problems, especially chronic ones with
a good example for osteoarthritis.

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We are just learning just now how cats
can mimic these signs of the chronic

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pain, for example, and we might not
reveal this during the examination

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because we only see the cat in this
unnatural stressful environment

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and it behaves very differently.

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And these two things, these, like
how caregiver is able to observe the

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cat, how they can report on these 10
questions and also how accurate is

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our basic clinical examination when
we are using just our like basic

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things we do as initial examination.

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These things could have been
responsible for the weaker relationship

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and would like to learn more if we
will collect the, the more data.

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. Yaiza Gomez-Mejias: And now I will
be interviewing Sam Taylor and Rachel

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Korman about the JFMS guidelines
on diagnosis and treatment of lower

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urinary tract disease in cats.

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Did you find it challenging to
coordinate the work in these guidelines?

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Sam Taylor: The challenges are,
we've wanted to write these

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guidelines for some years actually.

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And the hesitation has been, there's
quite conflicting literature on certain

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areas of urinary tract disease in cats.

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And there are some areas that
are quite poorly studied.

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And so we weren't quite brave
enough before to launch into it.

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And then we thought, actually, although
there are those controversies, that

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shouldn't put us off writing a guideline
because people still need to deal with

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these cases, which are extremely common
in both primary care and referral.

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So we decided to be brave and face
some of those controversies, look at

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the literature and acknowledge that
there are areas that are understudied,

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but to get that consensus from people
who see a lot of cases, like Rachel,

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from different countries  around the
world and from experts like Professor

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Buffington, who spent their whole life
studying FIC and bring them all together

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and produce something that hopefully
is really practical for people to use.

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And I'm really glad we did.

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And I hope we've navigated some of
those challenges effectively, but I

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think there's a real need out there to
support people in managing these cases.

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So yes, challenging, but
hopefully we've managed it.

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Yaiza Gomez-Mejias: And why has
the terminology in this area of

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medicine changed so much over the

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years?

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Rachel Korman: It's similar with many
other different sort of processes where

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different groups have similar names for
similar presentations and I think it

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just takes a combined focus group to
sit down and really try and make sure

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that everybody's on the same page and
understanding sort of the specific aspects

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that we're talking about for each group.

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So I think that's where sort of the
consensus part of it really comes

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into it is  just to try and bring
all of the different aspects of it

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under one umbrella so that we can
try and get better comparisons.

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Sam Taylor: Yeah, I think it helps if you
can have some clarity in this, because

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then when you talk about it or you
study it, everyone knows what you mean.

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And it was important to me in
these guidelines that we did really

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talk about the fact that flitted
or FLUTD is not a diagnosis.

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I found that quite frustrating and I
hear people say the cat's got FLUTD.

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And that's not really very helpful, is it?

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A cat's got FLUTD.

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What does that mean?

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And we tried to explain in the guidelines
that actually there are quite a few

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different diseases that can cause lower
urinary tract signs, but we shouldn't

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just label these cats as having FLUTD.

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We still need to investigate them.

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We need to see if they've got
urolithiasis, if they've got cystitis.

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And so there's a real drive to
move away from some of those terms.

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And actually, feline idiopathic
cystitis is not the best term.

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The trouble with that term is that
owners don't understand the word

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idiopathic and owners associate
the term cystitis with infection.

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So it gives you a very problematic
way of explaining a disease to owners.

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We don't really need the feline
bit, it's a cat in front of us.

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And in human medicine, that is
called bladder pain syndrome,

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rather than idiopathic cystitis.

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And so we discuss in the guidelines,
should we give that a better name so

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the owners understand it's a syndrome
and actually a systemic disorder.

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And what we see in the hematuria
and things is just the bladder's

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expression of that systemic disease.

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And I love the way that

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Professor Buffington describes it, that
we should think about this condition

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affecting the whole cat and it's just
that the bladder is expressing that

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stress so there's work to do and we'll
still need more conversations about this

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terminology, but hopefully people can
think about this not being a diagnosis.

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That's not an end point, FLUTD,
we've got to do a bit more.

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Yaiza Gomez-Mejias: Yeah, there are
so many challenges when it comes

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to this type  of science, not just
because the problem in some of the

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diseases seems multifactorial, but also
because the urinary tract has a very

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few ways of express itself as well.

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Starting from the beginning, from
the history taking, what's the most

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relevant information we should gather
before deciding on the testing and

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deciding how proactive we should be
in obtaining an accurate diagnosis?

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Rachel Korman: I guess there's a, quite
a few things that I always want to

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know right at the very start, the first
is obviously if you're dealing with

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a male or a female cat because that
also just helps to highlight a little

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bit the urgency, for example, complete
obstruction of the urethra, which is

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obviously a lot more common in male cats.

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A lot of the history taking that I start
off with is really evaluating whether

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the cat is an indoor or outdoor cat,
how  many cats are housed together?

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Is it a multi cat household
or a single cat household?

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And we like to get a lot of information
about litter box access, types of litter

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boxes, how many litter boxes, locations
in the house, because a lot of that

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gives us risk factors potentially for
some of the Behavioural aspects that

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we may want to focus on as part of
our treatment further down the line.

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I'm very keen to find out the dietary
aspect of what cats are receiving.

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So the history taking component takes
an awful lot of time and it's really

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beneficial, I think, to have a pre
written template, just to make sure

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that you're not missing any of the
common aspects that you need to cover.

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Yaiza Gomez-Mejias: Would you
like to add anything, Sam?

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Sam Taylor: Yeah, I think
that's really important.

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As Rachel was talking, I was thinking
about how often when I read the history

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of cats that are referred, that that
kind of  information is not included.

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And I'm really boring when I mark
people's case reports for various

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things that I just find myself repeating
myself saying, what's the diet?

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What's the lifestyle?

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Because that's the unique
thing about cats, isn't it?

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You can have a cat, like my cat
that goes out and kills moles and

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birds and all sorts of things.

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And you can have a cat that sleeps
on the sofa all day and they're

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obviously going to have quite different
risk factors for lots of things.

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So yeah, I really, I like
what Rachel was saying about

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getting that complete history.

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It's not just this, they're
fed a complete diet.

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It's what diet and do
they have access outdoors?

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How many litter trays do they have?

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And we had a case just this week that
came in for exactly low urinary tract

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signs and turned out there were about
five cats in the home and one litter tray.

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And if we hadn't asked that
question, we wouldn't have got that

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really crucial bit of information.

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So yeah, I think that's very important.

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Yaiza Gomez-Mejias:
Thank you for listening.

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If you're an iCatCare Veterinary Society
member, don't forget that you can access

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00:15:40,320 --> 00:15:43,840
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We'll be back again next month
with more from the world of

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feline medicine and JFMS.