Epilepsy Sparks Insights

Molecular Neuropathologist & PI Katja Kobow explains her research into unraveling the intricate interplay between epigenetic alterations and the development of epilepsy, specifically in the context of the adult post-mitotic brain.
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πŸ”— Website & more about Katja: πŸ‘‡πŸ»
https://www.torierobinson.com/epilepsy-sparks-insights/katja-kobow-brain-tissue-for-epilepsy-research-neuropathology
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! πŸ‘‡πŸ» https://www.epilepsysparks.com/glossary
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Show Notes

Award-winning molecular neuropathologist & PI Katja Kobow explains her research into unraveling the intricate interplay between epigenetic alterations and the development of epilepsy, specifically in the context of the adult post-mitotic brain.

πŸ”— Website & more about Katja: πŸ‘‡πŸ»
katja-kobow-brain-tissue-for-epilepsy-research-neuropathology

Chapters πŸ“–
00:00 Meet Katja
00:52 What is neuropathology?
01:49 Obtaining and using brain tissue
04:37 Research into epigenetic mechanisms in drug-resistant epilepsy
06:39 Causes of epilepsy and epigenetics as a marker
09:12 Identifying cell abnormalities through DNA methylation!
10:44 Informing clinician of patient histological/structural abnormalities
12:33 Not reporting epigenetic markers to influence clinical decision-making, yet
13:19 Promising results from molecular diagnostic biomarkers - brain & blood
15:00 Excited but not doing a Theranos!
17:31 Managing people's dreams about ultra-complex epigenetics
18:27 Current foci: diagnostic and patient stratification aspects
18:44 Educating the wider public re epilepsy research - money and exciting
20:28 Check out kobowlab.org
21:13 Conclusion

πŸ”€ Don’t understand terms used? Check out the Epilepsy Sparks Glossary!
epilepsysparks.com/glossary

πŸ“² Join us on social media!
〰️ LinkedIn https://www.linkedin.com/company/epilepsy-sparks
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〰️ Facebook https://www.facebook.com/epilepsysparks
〰️ TikTok https://www.tiktok.com/@epilepsysparks
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What is Epilepsy Sparks Insights?

Sparking interest and understanding in the epilepsies whilst bridging the communication gap between epilepsy patients, clinicians, scientists, geneticists – and the world. Hosted by Torie Robinson.
**NOT FOR CLINICAL OR PATIENT DECISION-MAKING*
Visit www.torierobinson.com & www.epilepsysparks.com.