{"version":"1.0.0","segments":[{"speaker":"Nathalie Dowgray","startTime":2.67,"endTime":4.947,"body":"Hello welcome"},{"speaker":"Nathalie Dowgray","startTime":2.67,"endTime":4.947,"body":"to the second episode of"},{"speaker":"Nathalie Dowgray","startTime":5.006,"endTime":8.662,"body":"Chattering With ISFM. This month"},{"speaker":"Nathalie Dowgray","startTime":5.006,"endTime":8.662,"body":"we have the first of our two"},{"speaker":"Nathalie Dowgray","startTime":8.722,"endTime":12.317,"body":"episodes on feline infectious"},{"speaker":"Nathalie Dowgray","startTime":8.722,"endTime":12.317,"body":"peritonitis. In June ISFMs own"},{"speaker":"Nathalie Dowgray","startTime":12.377,"endTime":15.373,"body":"Sam Taylor sat down at our"},{"speaker":"Nathalie Dowgray","startTime":12.377,"endTime":15.373,"body":"Congress in Rhodes with"},{"speaker":"Nathalie Dowgray","startTime":15.433,"endTime":19.088,"body":"professors Danièlle Gunn-Moore"},{"speaker":"Nathalie Dowgray","startTime":15.433,"endTime":19.088,"body":"and Séverine Tasker to discuss"},{"speaker":"Nathalie Dowgray","startTime":19.148,"endTime":22.863,"body":"the latest developments in the"},{"speaker":"Nathalie Dowgray","startTime":19.148,"endTime":22.863,"body":"diagnosis and treatment of FIP."},{"speaker":"Nathalie Dowgray","startTime":22.923,"endTime":25.74,"body":"We hope you enjoy part one of"},{"speaker":"Nathalie Dowgray","startTime":22.923,"endTime":25.74,"body":"their discussion."},{"speaker":"Sam Taylor","startTime":29.07,"endTime":31.02,"body":"Just with a little"},{"speaker":"Sam Taylor","startTime":29.07,"endTime":31.02,"body":"bit of background for those of"},{"speaker":"Sam Taylor","startTime":31.02,"endTime":33.6,"body":"you listening from around the"},{"speaker":"Sam Taylor","startTime":31.02,"endTime":33.6,"body":"world, the reason we're doing"},{"speaker":"Sam Taylor","startTime":33.6,"endTime":38.7,"body":"this is that for about a year"},{"speaker":"Sam Taylor","startTime":33.6,"endTime":38.7,"body":"now in the UK, and longer in"},{"speaker":"Sam Taylor","startTime":38.7,"endTime":42.75,"body":"Australia, we've had"},{"speaker":"Sam Taylor","startTime":38.7,"endTime":42.75,"body":"availability of antiviral drugs"},{"speaker":"Sam Taylor","startTime":42.96,"endTime":45.72,"body":"that have proved and are proving"},{"speaker":"Sam Taylor","startTime":42.96,"endTime":45.72,"body":"to be very effective at even"},{"speaker":"Sam Taylor","startTime":45.72,"endTime":46.86,"body":"curing FIP. And so we just"},{"speaker":"Sam Taylor","startTime":45.72,"endTime":46.86,"body":"wanted to go through a bit of"},{"speaker":"Sam Taylor","startTime":46.86,"endTime":48.0,"body":"background, some tips on"},{"speaker":"Sam Taylor","startTime":46.86,"endTime":48.0,"body":"diagnosis, and then we'll talk"},{"speaker":"Sam Taylor","startTime":48.0,"endTime":49.17,"body":"about these treatments. So I"},{"speaker":"Sam Taylor","startTime":48.0,"endTime":49.17,"body":"want to just go back a step"},{"speaker":"Sam Taylor","startTime":49.17,"endTime":50.25,"body":"because we can't understand"},{"speaker":"Sam Taylor","startTime":49.17,"endTime":50.25,"body":"treatments if we don't"},{"speaker":"Sam Taylor","startTime":50.25,"endTime":51.36,"body":"understand the disease. And so"},{"speaker":"Sam Taylor","startTime":50.25,"endTime":51.36,"body":"I'm going to go to Danièlle and"},{"speaker":"Sam Taylor","startTime":51.36,"endTime":53.34,"body":"just ask you, for people"},{"speaker":"Sam Taylor","startTime":51.36,"endTime":53.34,"body":"watching, can you just remind us"},{"speaker":"Sam Taylor","startTime":53.61,"endTime":57.51,"body":"the current thoughts on how"},{"speaker":"Sam Taylor","startTime":53.61,"endTime":57.51,"body":"Coronavirus causes FIP?"},{"speaker":"Danièlle Gunn-Moore","startTime":58.23,"endTime":60.66,"body":"Well, it's"},{"speaker":"Danièlle Gunn-Moore","startTime":58.23,"endTime":60.66,"body":"not nailed down yet. But our"},{"speaker":"Danièlle Gunn-Moore","startTime":60.66,"endTime":63.78,"body":"understanding is you've got the"},{"speaker":"Danièlle Gunn-Moore","startTime":60.66,"endTime":63.78,"body":"enteric corona, feline"},{"speaker":"Danièlle Gunn-Moore","startTime":63.78,"endTime":68.37,"body":"coronavirus, in most cat bowels,"},{"speaker":"Danièlle Gunn-Moore","startTime":63.78,"endTime":68.37,"body":"most cats are positive,"},{"speaker":"Danièlle Gunn-Moore","startTime":68.37,"endTime":71.79,"body":"particularly if they're in"},{"speaker":"Danièlle Gunn-Moore","startTime":68.37,"endTime":71.79,"body":"large, multi-cat households. And"},{"speaker":"Danièlle Gunn-Moore","startTime":71.82,"endTime":76.56,"body":"those viruses live there quite"},{"speaker":"Danièlle Gunn-Moore","startTime":71.82,"endTime":76.56,"body":"happily living, no problem. But"},{"speaker":"Danièlle Gunn-Moore","startTime":76.74,"endTime":80.76,"body":"they mutate, these viruses are"},{"speaker":"Danièlle Gunn-Moore","startTime":76.74,"endTime":80.76,"body":"big viruses and every single"},{"speaker":"Danièlle Gunn-Moore","startTime":80.76,"endTime":83.76,"body":"mutation, the daughter is"},{"speaker":"Danièlle Gunn-Moore","startTime":80.76,"endTime":83.76,"body":"slightly different to the"},{"speaker":"Danièlle Gunn-Moore","startTime":83.76,"endTime":87.93,"body":"mother. And every now and again,"},{"speaker":"Danièlle Gunn-Moore","startTime":83.76,"endTime":87.93,"body":"the viruses jump out of the"},{"speaker":"Danièlle Gunn-Moore","startTime":87.93,"endTime":91.05,"body":"bowel into the blood supply. And"},{"speaker":"Danièlle Gunn-Moore","startTime":87.93,"endTime":91.05,"body":"they go in particularly"},{"speaker":"Danièlle Gunn-Moore","startTime":91.11,"endTime":96.24,"body":"monocytes/macrophages and that's"},{"speaker":"Danièlle Gunn-Moore","startTime":91.11,"endTime":96.24,"body":"kind of step number one, and"},{"speaker":"Danièlle Gunn-Moore","startTime":96.24,"endTime":99.03,"body":"they're gonna start replicating"},{"speaker":"Danièlle Gunn-Moore","startTime":96.24,"endTime":99.03,"body":"and it's a fight then between"},{"speaker":"Danièlle Gunn-Moore","startTime":99.03,"endTime":103.14,"body":"the cat's immune system i.e. the"},{"speaker":"Danièlle Gunn-Moore","startTime":99.03,"endTime":103.14,"body":"macrophages to stop the virus"},{"speaker":"Danièlle Gunn-Moore","startTime":103.14,"endTime":107.46,"body":"replicating and the virus"},{"speaker":"Danièlle Gunn-Moore","startTime":103.14,"endTime":107.46,"body":"desperately trying to replicate."},{"speaker":"Danièlle Gunn-Moore","startTime":107.97,"endTime":112.41,"body":"You build up these clouds, quasi"},{"speaker":"Danièlle Gunn-Moore","startTime":107.97,"endTime":112.41,"body":"species clouds, of viruses that"},{"speaker":"Danièlle Gunn-Moore","startTime":112.41,"endTime":116.94,"body":"are very similar. But some of"},{"speaker":"Danièlle Gunn-Moore","startTime":112.41,"endTime":116.94,"body":"them are more pathogenic than"},{"speaker":"Danièlle Gunn-Moore","startTime":116.94,"endTime":120.84,"body":"others. And so you get more"},{"speaker":"Danièlle Gunn-Moore","startTime":116.94,"endTime":120.84,"body":"mutations that allow the virus"},{"speaker":"Danièlle Gunn-Moore","startTime":120.84,"endTime":125.04,"body":"to replicate even more, and then"},{"speaker":"Danièlle Gunn-Moore","startTime":120.84,"endTime":125.04,"body":"eventually can take a step. And"},{"speaker":"Danièlle Gunn-Moore","startTime":125.07,"endTime":129.63,"body":"they can now trigger FIP, that's"},{"speaker":"Danièlle Gunn-Moore","startTime":125.07,"endTime":129.63,"body":"a very shortened version"},{"speaker":"Sam Taylor","startTime":130.169,"endTime":133.401,"body":"It's a good version,"},{"speaker":"Sam Taylor","startTime":130.169,"endTime":133.401,"body":"thank you. Coming to you Sév,"},{"speaker":"Sam Taylor","startTime":133.466,"endTime":137.539,"body":"one of the things that we get a"},{"speaker":"Sam Taylor","startTime":133.466,"endTime":137.539,"body":"lot of questions about on our -"},{"speaker":"Sam Taylor","startTime":137.604,"endTime":141.613,"body":"we run an email advice service"},{"speaker":"Sam Taylor","startTime":137.604,"endTime":141.613,"body":"for FIP - and one of the things"},{"speaker":"Sam Taylor","startTime":141.677,"endTime":144.975,"body":"we get asked about a lot is"},{"speaker":"Sam Taylor","startTime":141.677,"endTime":144.975,"body":"diagnosis. Because it's"},{"speaker":"Sam Taylor","startTime":145.039,"endTime":148.596,"body":"something that can be really,"},{"speaker":"Sam Taylor","startTime":145.039,"endTime":148.596,"body":"really confusing. For our"},{"speaker":"Sam Taylor","startTime":148.66,"endTime":152.604,"body":"general practitioners, who are"},{"speaker":"Sam Taylor","startTime":148.66,"endTime":152.604,"body":"often time and perhaps, funds,"},{"speaker":"Sam Taylor","startTime":152.669,"endTime":157.26,"body":"limited what do you advise as a"},{"speaker":"Sam Taylor","startTime":152.669,"endTime":157.26,"body":"sort of approach to making a diagnosis?"},{"speaker":"Séverine Tasker","startTime":157.26,"endTime":159.72,"body":"Yeah, it's a"},{"speaker":"Séverine Tasker","startTime":157.26,"endTime":159.72,"body":"really good question. So I think"},{"speaker":"Séverine Tasker","startTime":159.72,"endTime":162.18,"body":"it's worth thinking about, first"},{"speaker":"Séverine Tasker","startTime":159.72,"endTime":162.18,"body":"of all, that actually, our"},{"speaker":"Séverine Tasker","startTime":162.18,"endTime":165.3,"body":"approach now that we've got a"},{"speaker":"Séverine Tasker","startTime":162.18,"endTime":165.3,"body":"treatment available makes it a"},{"speaker":"Séverine Tasker","startTime":165.3,"endTime":169.05,"body":"little bit different, because"},{"speaker":"Séverine Tasker","startTime":165.3,"endTime":169.05,"body":"previously, it was about being"},{"speaker":"Séverine Tasker","startTime":169.05,"endTime":172.56,"body":"absolutely sure that we had the"},{"speaker":"Séverine Tasker","startTime":169.05,"endTime":172.56,"body":"diagnosis before often having to"},{"speaker":"Séverine Tasker","startTime":172.56,"endTime":176.07,"body":"sadly put the cat to sleep."},{"speaker":"Séverine Tasker","startTime":172.56,"endTime":176.07,"body":"Whereas now, we're really aiming"},{"speaker":"Séverine Tasker","startTime":176.07,"endTime":180.36,"body":"for being as confident as that"},{"speaker":"Séverine Tasker","startTime":176.07,"endTime":180.36,"body":"being a likely diagnosis as"},{"speaker":"Séverine Tasker","startTime":180.36,"endTime":184.59,"body":"possible, in order to then think"},{"speaker":"Séverine Tasker","startTime":180.36,"endTime":184.59,"body":"about a treatment if the client"},{"speaker":"Séverine Tasker","startTime":184.59,"endTime":187.8,"body":"can afford it, because we have"},{"speaker":"Séverine Tasker","startTime":184.59,"endTime":187.8,"body":"to bear in mind that the"},{"speaker":"Séverine Tasker","startTime":187.92,"endTime":191.94,"body":"antivirals were so lucky to have"},{"speaker":"Séverine Tasker","startTime":187.92,"endTime":191.94,"body":"them, but they are expensive."},{"speaker":"Séverine Tasker","startTime":191.94,"endTime":195.18,"body":"And we also therefore don't want"},{"speaker":"Séverine Tasker","startTime":191.94,"endTime":195.18,"body":"to be spending a huge amount of"},{"speaker":"Séverine Tasker","startTime":195.18,"endTime":198.57,"body":"money diagnostically and then"},{"speaker":"Séverine Tasker","startTime":195.18,"endTime":198.57,"body":"not having any funds available"},{"speaker":"Séverine Tasker","startTime":198.57,"endTime":201.87,"body":"for treatment. So it sort of"},{"speaker":"Séverine Tasker","startTime":198.57,"endTime":201.87,"body":"alters the dynamics of, of what"},{"speaker":"Séverine Tasker","startTime":201.87,"endTime":205.56,"body":"we want to do diagnostically a"},{"speaker":"Séverine Tasker","startTime":201.87,"endTime":205.56,"body":"little bit different. So I think"},{"speaker":"Séverine Tasker","startTime":205.56,"endTime":209.01,"body":"we should be aiming to be as"},{"speaker":"Séverine Tasker","startTime":205.56,"endTime":209.01,"body":"confident as possible, even if"},{"speaker":"Séverine Tasker","startTime":209.01,"endTime":213.27,"body":"we don't nail the diagnosis. In"},{"speaker":"Séverine Tasker","startTime":209.01,"endTime":213.27,"body":"terms of more specific"},{"speaker":"Séverine Tasker","startTime":213.27,"endTime":217.17,"body":"diagnostics, if you can't go"},{"speaker":"Séverine Tasker","startTime":213.27,"endTime":217.17,"body":"through them all just now, but I"},{"speaker":"Séverine Tasker","startTime":217.17,"endTime":221.01,"body":"think really try and find fluid."},{"speaker":"Séverine Tasker","startTime":217.17,"endTime":221.01,"body":"You know, if you can find a"},{"speaker":"Séverine Tasker","startTime":221.01,"endTime":225.75,"body":"slither of fluid in that cat and"},{"speaker":"Séverine Tasker","startTime":221.01,"endTime":225.75,"body":"get a sample of that fluid that"},{"speaker":"Séverine Tasker","startTime":225.75,"endTime":228.96,"body":"really gives you something that"},{"speaker":"Séverine Tasker","startTime":225.75,"endTime":228.96,"body":"diagnostically is really, really"},{"speaker":"Séverine Tasker","startTime":228.96,"endTime":232.8,"body":"useful. From the point of view"},{"speaker":"Séverine Tasker","startTime":228.96,"endTime":232.8,"body":"of cytology on that fluid, the"},{"speaker":"Séverine Tasker","startTime":232.8,"endTime":237.15,"body":"protein levels in that fluid,"},{"speaker":"Séverine Tasker","startTime":232.8,"endTime":237.15,"body":"and then also if funds allow a"},{"speaker":"Séverine Tasker","startTime":237.15,"endTime":239.16,"body":"PCR on that fluid as well."},{"speaker":"Sam Taylor","startTime":239.67,"endTime":242.496,"body":"Yeah. Actually Sév,"},{"speaker":"Sam Taylor","startTime":239.67,"endTime":242.496,"body":"well both of you have mentioned"},{"speaker":"Sam Taylor","startTime":242.551,"endTime":246.097,"body":"PCR, and that can be perhaps for"},{"speaker":"Sam Taylor","startTime":242.551,"endTime":246.097,"body":"practitioners a little bit of a"},{"speaker":"Sam Taylor","startTime":246.153,"endTime":249.09,"body":"minefield because we've got what"},{"speaker":"Sam Taylor","startTime":246.153,"endTime":249.09,"body":"I call a Yes/No PCR."},{"speaker":"Séverine Tasker","startTime":249.09,"endTime":249.75,"body":"Yeah, yeah."},{"speaker":"Sam Taylor","startTime":250.17,"endTime":251.82,"body":"We've got a"},{"speaker":"Sam Taylor","startTime":250.17,"endTime":251.82,"body":"quantitive PCR and then we've"},{"speaker":"Sam Taylor","startTime":251.82,"endTime":255.09,"body":"got a mutation PCR could you"},{"speaker":"Sam Taylor","startTime":251.82,"endTime":255.09,"body":"just explain?"},{"speaker":"Séverine Tasker","startTime":255.09,"endTime":259.38,"body":"Yeah, yes. So"},{"speaker":"Séverine Tasker","startTime":255.09,"endTime":259.38,"body":"we've talked about PCR, it is RT"},{"speaker":"Séverine Tasker","startTime":259.38,"endTime":263.31,"body":"PCR because Coronavirus is an"},{"speaker":"Séverine Tasker","startTime":259.38,"endTime":263.31,"body":"RNA virus so we have to do"},{"speaker":"Séverine Tasker","startTime":263.31,"endTime":267.57,"body":"reverse transcriptase PCR, but"},{"speaker":"Séverine Tasker","startTime":263.31,"endTime":267.57,"body":"we'll just say PCR for today. So"},{"speaker":"Séverine Tasker","startTime":267.57,"endTime":273.36,"body":"PCR is basically looking for the"},{"speaker":"Séverine Tasker","startTime":267.57,"endTime":273.36,"body":"RNA in the Coronavirus that's in"},{"speaker":"Séverine Tasker","startTime":273.36,"endTime":276.72,"body":"the cat. And what we've got to"},{"speaker":"Séverine Tasker","startTime":273.36,"endTime":276.72,"body":"remember is there's different"},{"speaker":"Séverine Tasker","startTime":276.72,"endTime":281.37,"body":"types of PCR out there. So the"},{"speaker":"Séverine Tasker","startTime":276.72,"endTime":281.37,"body":"older type PCR what we sometimes"},{"speaker":"Séverine Tasker","startTime":281.37,"endTime":285.81,"body":"call conventional PCR is doing"},{"speaker":"Séverine Tasker","startTime":281.37,"endTime":285.81,"body":"that PCR and then running the"},{"speaker":"Séverine Tasker","startTime":285.81,"endTime":289.89,"body":"sample on a gel and then looking"},{"speaker":"Séverine Tasker","startTime":285.81,"endTime":289.89,"body":"is it there? Yes. Is it not"},{"speaker":"Séverine Tasker","startTime":289.89,"endTime":293.28,"body":"there? No. Is there a band"},{"speaker":"Séverine Tasker","startTime":289.89,"endTime":293.28,"body":"there? Yes. Is there no band?"},{"speaker":"Séverine Tasker","startTime":293.31,"endTime":296.97,"body":"No. And it's so, it was a yes no"},{"speaker":"Séverine Tasker","startTime":293.31,"endTime":296.97,"body":"answer to 'is the coronavirus"},{"speaker":"Séverine Tasker","startTime":296.97,"endTime":300.69,"body":"there?', which you know, is"},{"speaker":"Séverine Tasker","startTime":296.97,"endTime":300.69,"body":"helpful in certain situations"},{"speaker":"Séverine Tasker","startTime":300.69,"endTime":303.09,"body":"when you wanted to know whether"},{"speaker":"Séverine Tasker","startTime":300.69,"endTime":303.09,"body":"something is there or not."},{"speaker":"Séverine Tasker","startTime":303.39,"endTime":307.53,"body":"Quantitative PCR goes up another"},{"speaker":"Séverine Tasker","startTime":303.39,"endTime":307.53,"body":"stage because it's not only"},{"speaker":"Séverine Tasker","startTime":307.53,"endTime":311.46,"body":"telling you 'yes/no' but it's"},{"speaker":"Séverine Tasker","startTime":307.53,"endTime":311.46,"body":"saying yes, there's a small"},{"speaker":"Séverine Tasker","startTime":311.46,"endTime":314.52,"body":"amount, a medium amount, or"},{"speaker":"Séverine Tasker","startTime":311.46,"endTime":314.52,"body":"there's a lot of it about"},{"speaker":"Séverine Tasker","startTime":314.52,"endTime":318.84,"body":"depending on what PCR assay is"},{"speaker":"Séverine Tasker","startTime":314.52,"endTime":318.84,"body":"being used by the lab and what"},{"speaker":"Séverine Tasker","startTime":318.84,"endTime":323.34,"body":"controls that they've done"},{"speaker":"Séverine Tasker","startTime":318.84,"endTime":323.34,"body":"previously. So quantitative PCR,"},{"speaker":"Séverine Tasker","startTime":323.34,"endTime":327.18,"body":"for me, is what I find most"},{"speaker":"Séverine Tasker","startTime":323.34,"endTime":327.18,"body":"useful because I'm really sort"},{"speaker":"Séverine Tasker","startTime":327.18,"endTime":332.49,"body":"of finding, we know from the"},{"speaker":"Séverine Tasker","startTime":327.18,"endTime":332.49,"body":"pathogenesis that normal non FIP"},{"speaker":"Séverine Tasker","startTime":332.67,"endTime":336.09,"body":"cats can have some Coronavirus"},{"speaker":"Séverine Tasker","startTime":332.67,"endTime":336.09,"body":"systemically, it's not that"},{"speaker":"Séverine Tasker","startTime":336.09,"endTime":340.02,"body":"common, but they can have that,"},{"speaker":"Séverine Tasker","startTime":336.09,"endTime":340.02,"body":"but they have lower levels than"},{"speaker":"Séverine Tasker","startTime":340.02,"endTime":344.13,"body":"cats with FIP. So that"},{"speaker":"Séverine Tasker","startTime":340.02,"endTime":344.13,"body":"quantitive PCR, if you can get a"},{"speaker":"Séverine Tasker","startTime":344.13,"endTime":348.36,"body":"sample from an area where there"},{"speaker":"Séverine Tasker","startTime":344.13,"endTime":348.36,"body":"is likely pathology that's"},{"speaker":"Séverine Tasker","startTime":348.36,"endTime":352.29,"body":"consistent with FIP, and you've"},{"speaker":"Séverine Tasker","startTime":348.36,"endTime":352.29,"body":"got a lot of Coronavirus in"},{"speaker":"Séverine Tasker","startTime":352.29,"endTime":355.38,"body":"there, that really makes me a"},{"speaker":"Séverine Tasker","startTime":352.29,"endTime":355.38,"body":"lot more confident that I'm"},{"speaker":"Séverine Tasker","startTime":355.38,"endTime":356.34,"body":"dealing with the FIP."},{"speaker":"Sam Taylor","startTime":357.0,"endTime":359.25,"body":"And just coming to"},{"speaker":"Sam Taylor","startTime":357.0,"endTime":359.25,"body":"you Danièlle, I suppose being"},{"speaker":"Sam Taylor","startTime":359.25,"endTime":362.25,"body":"slightly controversial. There's"},{"speaker":"Sam Taylor","startTime":359.25,"endTime":362.25,"body":"a few tests that maybe we don't"},{"speaker":"Sam Taylor","startTime":362.25,"endTime":367.08,"body":"like as much. You know, my"},{"speaker":"Sam Taylor","startTime":362.25,"endTime":367.08,"body":"feelings on serology. What are"},{"speaker":"Sam Taylor","startTime":367.08,"endTime":369.06,"body":"your feelings on serology?"},{"speaker":"Sam Taylor","startTime":367.08,"endTime":369.06,"body":"Because we know that our"},{"speaker":"Sam Taylor","startTime":369.06,"endTime":371.58,"body":"colleagues are doing it."},{"speaker":"Danièlle Gunn-Moore","startTime":372.03,"endTime":373.89,"body":"I can"},{"speaker":"Danièlle Gunn-Moore","startTime":372.03,"endTime":373.89,"body":"remember Professor Niels"},{"speaker":"Danièlle Gunn-Moore","startTime":373.89,"endTime":378.18,"body":"Pedersen, saying when I was"},{"speaker":"Danièlle Gunn-Moore","startTime":373.89,"endTime":378.18,"body":"still a baby vet that more cats"},{"speaker":"Danièlle Gunn-Moore","startTime":378.18,"endTime":383.64,"body":"had died from having a positive"},{"speaker":"Danièlle Gunn-Moore","startTime":378.18,"endTime":383.64,"body":"Corona antibody test than ever"},{"speaker":"Danièlle Gunn-Moore","startTime":383.67,"endTime":389.13,"body":"had FIP. And I think that is"},{"speaker":"Danièlle Gunn-Moore","startTime":383.67,"endTime":389.13,"body":"even more correct now. And so"},{"speaker":"Danièlle Gunn-Moore","startTime":389.19,"endTime":392.76,"body":"it's really important. If"},{"speaker":"Danièlle Gunn-Moore","startTime":389.19,"endTime":392.76,"body":"there's one take home message,"},{"speaker":"Danièlle Gunn-Moore","startTime":392.79,"endTime":397.17,"body":"please. Just because they're"},{"speaker":"Danièlle Gunn-Moore","startTime":392.79,"endTime":397.17,"body":"antibody positive, that doesn't"},{"speaker":"Danièlle Gunn-Moore","startTime":397.17,"endTime":401.58,"body":"mean anything, it means they've"},{"speaker":"Danièlle Gunn-Moore","startTime":397.17,"endTime":401.58,"body":"met Coronavirus, whoopee."},{"speaker":"Danièlle Gunn-Moore","startTime":401.97,"endTime":404.91,"body":"They're ubiquitous, they're"},{"speaker":"Danièlle Gunn-Moore","startTime":401.97,"endTime":404.91,"body":"everywhere. So just because"},{"speaker":"Danièlle Gunn-Moore","startTime":404.91,"endTime":407.67,"body":"they're positive, it doesn't"},{"speaker":"Danièlle Gunn-Moore","startTime":404.91,"endTime":407.67,"body":"mean anything and then people"},{"speaker":"Danièlle Gunn-Moore","startTime":407.67,"endTime":412.38,"body":"go, 'but its a really high"},{"speaker":"Danièlle Gunn-Moore","startTime":407.67,"endTime":412.38,"body":"level, so that means something"},{"speaker":"Danièlle Gunn-Moore","startTime":412.38,"endTime":415.17,"body":"important, doesn't it?'. No,"},{"speaker":"Danièlle Gunn-Moore","startTime":412.38,"endTime":415.17,"body":"some of the highest ones I've"},{"speaker":"Danièlle Gunn-Moore","startTime":415.17,"endTime":418.62,"body":"seen were completely normal.  It"},{"speaker":"Danièlle Gunn-Moore","startTime":415.17,"endTime":418.62,"body":"was a litter of Siamese kittens,"},{"speaker":"Danièlle Gunn-Moore","startTime":418.77,"endTime":423.48,"body":"and they were all through the"},{"speaker":"Danièlle Gunn-Moore","startTime":418.77,"endTime":423.48,"body":"ceiling. And in wet FIP they can"},{"speaker":"Danièlle Gunn-Moore","startTime":423.51,"endTime":427.74,"body":"even have a zero antibody,"},{"speaker":"Danièlle Gunn-Moore","startTime":423.51,"endTime":427.74,"body":"because it's all caught up in"},{"speaker":"Danièlle Gunn-Moore","startTime":427.74,"endTime":429.24,"body":"the immune complexes."},{"speaker":"Sam Taylor","startTime":429.48,"endTime":432.06,"body":"And just before we"},{"speaker":"Sam Taylor","startTime":429.48,"endTime":432.06,"body":"move on to treatment, my last"},{"speaker":"Sam Taylor","startTime":432.06,"endTime":436.02,"body":"question, I'll come back to"},{"speaker":"Sam Taylor","startTime":432.06,"endTime":436.02,"body":"Danièlle again, faecal PCRs for"},{"speaker":"Sam Taylor","startTime":436.02,"endTime":439.26,"body":"Coronavirus. Now they're are on"},{"speaker":"Sam Taylor","startTime":436.02,"endTime":439.26,"body":"a lot of panels. And I know"},{"speaker":"Sam Taylor","startTime":439.26,"endTime":442.05,"body":"we're talking about FIP today"},{"speaker":"Sam Taylor","startTime":439.26,"endTime":442.05,"body":"and I'm sort of veering off a"},{"speaker":"Sam Taylor","startTime":442.05,"endTime":444.21,"body":"little bit but while we're"},{"speaker":"Sam Taylor","startTime":442.05,"endTime":444.21,"body":"talking about PCRs for"},{"speaker":"Sam Taylor","startTime":444.21,"endTime":447.33,"body":"Coronavirus, what are the"},{"speaker":"Sam Taylor","startTime":444.21,"endTime":447.33,"body":"circumstances that you would"},{"speaker":"Sam Taylor","startTime":447.33,"endTime":449.82,"body":"perform a Coronavirus PCR?"},{"speaker":"Danièlle Gunn-Moore","startTime":450.54,"endTime":452.22,"body":"It's"},{"speaker":"Danièlle Gunn-Moore","startTime":450.54,"endTime":452.22,"body":"another, it's actually really"},{"speaker":"Danièlle Gunn-Moore","startTime":452.22,"endTime":454.29,"body":"important because I'm seeing"},{"speaker":"Danièlle Gunn-Moore","startTime":452.22,"endTime":454.29,"body":"more and more that you know,"},{"speaker":"Danièlle Gunn-Moore","startTime":454.29,"endTime":459.0,"body":"with the advice ones coming"},{"speaker":"Danièlle Gunn-Moore","startTime":454.29,"endTime":459.0,"body":"through that it's faecal PCR"},{"speaker":"Danièlle Gunn-Moore","startTime":459.0,"endTime":462.99,"body":"positive so that means he's got"},{"speaker":"Danièlle Gunn-Moore","startTime":459.0,"endTime":462.99,"body":"FIP. No, it means he's got"},{"speaker":"Danièlle Gunn-Moore","startTime":463.14,"endTime":469.35,"body":"Coronavirus in his poop. And"},{"speaker":"Danièlle Gunn-Moore","startTime":463.14,"endTime":469.35,"body":"that the viruses that are living"},{"speaker":"Danièlle Gunn-Moore","startTime":469.35,"endTime":473.13,"body":"in his bowel, they haven't"},{"speaker":"Danièlle Gunn-Moore","startTime":469.35,"endTime":473.13,"body":"mutated to live in his blood."},{"speaker":"Danièlle Gunn-Moore","startTime":473.13,"endTime":476.43,"body":"It's the blood ones that we have"},{"speaker":"Danièlle Gunn-Moore","startTime":473.13,"endTime":476.43,"body":"to be worried about. So in fact,"},{"speaker":"Danièlle Gunn-Moore","startTime":476.64,"endTime":479.88,"body":"I'm not even going to"},{"speaker":"Danièlle Gunn-Moore","startTime":476.64,"endTime":479.88,"body":"contemplate looking at a faecal"},{"speaker":"Danièlle Gunn-Moore","startTime":479.88,"endTime":485.73,"body":"PCR for an FIP case. I'm going"},{"speaker":"Danièlle Gunn-Moore","startTime":479.88,"endTime":485.73,"body":"to keep it for the really the"},{"speaker":"Danièlle Gunn-Moore","startTime":485.73,"endTime":488.88,"body":"nasty chronic diarrhoeas where"},{"speaker":"Danièlle Gunn-Moore","startTime":485.73,"endTime":488.88,"body":"I've run out of every other"},{"speaker":"Danièlle Gunn-Moore","startTime":488.88,"endTime":492.66,"body":"differential and I'm thinking"},{"speaker":"Danièlle Gunn-Moore","startTime":488.88,"endTime":492.66,"body":"okay, maybe could this actually"},{"speaker":"Danièlle Gunn-Moore","startTime":492.66,"endTime":496.89,"body":"be one of those rare cases? That"},{"speaker":"Danièlle Gunn-Moore","startTime":492.66,"endTime":496.89,"body":"is actually a Coronavirus"},{"speaker":"Danièlle Gunn-Moore","startTime":496.89,"endTime":500.55,"body":"induced diarrhoea and that's"},{"speaker":"Danièlle Gunn-Moore","startTime":496.89,"endTime":500.55,"body":"where I would be using that PCR,"},{"speaker":"Danièlle Gunn-Moore","startTime":500.91,"endTime":506.97,"body":"or if I'm trying to clear a"},{"speaker":"Danièlle Gunn-Moore","startTime":500.91,"endTime":506.97,"body":"cattery of Coronavirus, and I'm"},{"speaker":"Danièlle Gunn-Moore","startTime":507.03,"endTime":509.91,"body":"trying to work out who the"},{"speaker":"Danièlle Gunn-Moore","startTime":507.03,"endTime":509.91,"body":"shedder is. So I'm going to"},{"speaker":"Danièlle Gunn-Moore","startTime":509.91,"endTime":512.76,"body":"check which cats are shedding"},{"speaker":"Danièlle Gunn-Moore","startTime":509.91,"endTime":512.76,"body":"which cats aren't so I can put"},{"speaker":"Danièlle Gunn-Moore","startTime":512.91,"endTime":516.33,"body":"the negatives together and try"},{"speaker":"Danièlle Gunn-Moore","startTime":512.91,"endTime":516.33,"body":"and find out which is the cat"},{"speaker":"Danièlle Gunn-Moore","startTime":516.33,"endTime":519.12,"body":"that's actually the chronic"},{"speaker":"Danièlle Gunn-Moore","startTime":516.33,"endTime":519.12,"body":"shedder. They'd be the terms,"},{"speaker":"Danièlle Gunn-Moore","startTime":519.15,"endTime":520.2,"body":"would you use them otherwise?"},{"speaker":"Séverine Tasker","startTime":520.2,"endTime":522.96,"body":"Yeah, I agree."},{"speaker":"Séverine Tasker","startTime":520.2,"endTime":522.96,"body":"And I think also I think, you"},{"speaker":"Séverine Tasker","startTime":522.96,"endTime":526.11,"body":"know, getting rid of Coronavirus"},{"speaker":"Séverine Tasker","startTime":522.96,"endTime":526.11,"body":"from a household is really"},{"speaker":"Séverine Tasker","startTime":526.11,"endTime":529.11,"body":"really difficult, isn't it? I've"},{"speaker":"Séverine Tasker","startTime":526.11,"endTime":529.11,"body":"only ever come across one"},{"speaker":"Séverine Tasker","startTime":529.11,"endTime":532.2,"body":"amazing client that managed to"},{"speaker":"Séverine Tasker","startTime":529.11,"endTime":532.2,"body":"do it. But there are there are"},{"speaker":"Séverine Tasker","startTime":532.2,"endTime":535.8,"body":"some times some very high"},{"speaker":"Séverine Tasker","startTime":532.2,"endTime":535.8,"body":"chronic shedders that at least"},{"speaker":"Séverine Tasker","startTime":535.8,"endTime":538.71,"body":"thinking about removing you"},{"speaker":"Séverine Tasker","startTime":535.8,"endTime":538.71,"body":"know, I always think about"},{"speaker":"Séverine Tasker","startTime":538.71,"endTime":542.49,"body":"Coronavirus load in a household"},{"speaker":"Séverine Tasker","startTime":538.71,"endTime":542.49,"body":"and just sort of try, you know,"},{"speaker":"Séverine Tasker","startTime":542.49,"endTime":545.25,"body":"because the more coronavirus"},{"speaker":"Séverine Tasker","startTime":542.49,"endTime":545.25,"body":"there is there, the more it"},{"speaker":"Séverine Tasker","startTime":545.25,"endTime":548.49,"body":"replicates, the more it"},{"speaker":"Séverine Tasker","startTime":545.25,"endTime":548.49,"body":"replicates badly and you know,"},{"speaker":"Séverine Tasker","startTime":548.52,"endTime":553.86,"body":"so but yeah, exactly those two"},{"speaker":"Séverine Tasker","startTime":548.52,"endTime":553.86,"body":"situations for me as well."},{"speaker":"Nathalie Dowgray","startTime":555.78,"endTime":557.34,"body":"Thank you for"},{"speaker":"Nathalie Dowgray","startTime":555.78,"endTime":557.34,"body":"listening to Chattering With"},{"speaker":"Nathalie Dowgray","startTime":557.4,"endTime":560.55,"body":"ISFM. The full version of this"},{"speaker":"Nathalie Dowgray","startTime":557.4,"endTime":560.55,"body":"roundtable discussion is"},{"speaker":"Nathalie Dowgray","startTime":560.55,"endTime":564.54,"body":"available for ISFM veterinary"},{"speaker":"Nathalie Dowgray","startTime":560.55,"endTime":564.54,"body":"members. To access it, please"},{"speaker":"Nathalie Dowgray","startTime":564.54,"endTime":568.89,"body":"log in to portal.icatcare.org"},{"speaker":"Nathalie Dowgray","startTime":564.54,"endTime":568.89,"body":"where you'll find not only this,"},{"speaker":"Nathalie Dowgray","startTime":569.04,"endTime":572.25,"body":"but also access to all of your"},{"speaker":"Nathalie Dowgray","startTime":569.04,"endTime":572.25,"body":"other ISFM member benefits,"},{"speaker":"Nathalie Dowgray","startTime":572.49,"endTime":576.06,"body":"including recordings from our"},{"speaker":"Nathalie Dowgray","startTime":572.49,"endTime":576.06,"body":"ISFM Congress's, monthly"},{"speaker":"Nathalie Dowgray","startTime":576.06,"endTime":580.2,"body":"webinars, the discussion forum"},{"speaker":"Nathalie Dowgray","startTime":576.06,"endTime":580.2,"body":"and much more. If you're not an"},{"speaker":"Nathalie Dowgray","startTime":580.2,"endTime":584.64,"body":"ISFM member, please visit our"},{"speaker":"Nathalie Dowgray","startTime":580.2,"endTime":584.64,"body":"icatcare.org to learn more. Tune"},{"speaker":"Nathalie Dowgray","startTime":584.64,"endTime":588.36,"body":"in next month for the second"},{"speaker":"Nathalie Dowgray","startTime":584.64,"endTime":588.36,"body":"part of this series on FIP and"},{"speaker":"Nathalie Dowgray","startTime":588.36,"endTime":591.3,"body":"do look out for a free open"},{"speaker":"Nathalie Dowgray","startTime":588.36,"endTime":591.3,"body":"access webinar brought to you"},{"speaker":"Nathalie Dowgray","startTime":591.3,"endTime":595.02,"body":"from IDEXX. That will be going"},{"speaker":"Nathalie Dowgray","startTime":591.3,"endTime":595.02,"body":"live on the 8th of December with"},{"speaker":"Nathalie Dowgray","startTime":595.02,"endTime":598.56,"body":"Bill Saxon and he's going to be"},{"speaker":"Nathalie Dowgray","startTime":595.02,"endTime":598.56,"body":"speaking on feline renal and"},{"speaker":"Nathalie Dowgray","startTime":598.56,"endTime":602.61,"body":"urinary health, how to optimise"},{"speaker":"Nathalie Dowgray","startTime":598.56,"endTime":602.61,"body":"sampling and diagnostics. See"},{"speaker":"Nathalie Dowgray","startTime":602.61,"endTime":603.72,"body":"you again next month"}]}